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Deep graph learning has advanced Alzheimer's (AD) disease classification from MRI, but most models remain correlational, confounding demographic and genetic factors with disease specific features. We present Causal-GCN, an interventional…

Machine Learning · Computer Science 2025-11-20 Pranay Kumar Peddi , Dhrubajyoti Ghosh

Fusing structural-functional images of the brain has shown great potential to analyze the deterioration of Alzheimer's disease (AD). However, it is a big challenge to effectively fuse the correlated and complementary information from…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Qiankun Zuo , Junren Pan , Shuqiang Wang

Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

Neurons and Cognition · Quantitative Biology 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. Early detection of AD is crucial for effective intervention and treatment. In this paper, we propose a novel approach…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-29 Yu Pu , Wei-Qiang Zhang

Computer-aided early diagnosis of Alzheimers Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research in recent years. Some recent studies have shown promising results in the AD and…

Computer Vision and Pattern Recognition · Computer Science 2018-01-19 Alexander Khvostikov , Karim Aderghal , Jenny Benois-Pineau , Andrey Krylov , Gwenaelle Catheline

Deep learning has become an important tool for Alzheimer's disease (AD) classification from structural MRI. Many existing studies analyze individual 2D slices extracted from MRI volumes, while clinical neuroimaging practice typically relies…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Md Sifat , Sania Akter , Akif Islam , Md. Ekramul Hamid , Abu Saleh Musa Miah , Najmul Hassan , Md Abdur Rahim , Jungpil Shin

Background: Alzheimer's disease and related dementias (ADRD) are progressive neurodegenerative conditions where early detection is vital for timely intervention and care. Spontaneous speech contains rich acoustic and linguistic markers that…

Computation and Language · Computer Science 2025-06-16 Jingyu Li , Lingchao Mao , Hairong Wang , Zhendong Wang , Xi Mao , Xuelei Sherry Ni

Alzheimer's Disease (AD) is a non-curable progressive neurodegenerative disorder that affects the human brain, leading to a decline in memory, cognitive abilities, and eventually, the ability to carry out daily tasks. Manual diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Santanu Roy , Archit Gupta , Shubhi Tiwari , Palak Sahu

With populations ageing, the number of people with dementia worldwide is expected to triple to 152 million by 2050. Seventy percent of cases are due to Alzheimer's disease (AD) pathology and there is a 10-20 year 'pre-clinical' period…

Artificial Intelligence · Computer Science 2021-04-30 Renjie Li , Xinyi Wang , Katherine Lawler , Saurabh Garg , Quan Bai , Jane Alty

Alzheimer's Disease (AD) is the most common form of dementia in the United States. Sleep is one of the lifestyle-related factors that has been shown critical for optimal cognitive function in old age. However, there is a lack of research…

Healthcare datasets often contain groups of highly correlated features, such as features from the same biological system. When feature selection is applied to these datasets to identify the most important features, the biases inherent in…

Machine Learning · Computer Science 2022-07-07 Annette Spooner , Gelareh Mohammadi , Perminder S. Sachdev , Henry Brodaty , Arcot Sowmya

Alzheimer's disease (AD) is an irreversible neurode generative disease of the brain.The disease may causes memory loss, difficulty communicating and disorientation. For the diagnosis of Alzheimer's disease, a series of scales are often…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Yelu Gao , Huang Huang , Lian Zhang

Introduction: Alzheimer's disease is a type of dementia in which early diagnosis plays a major rule in the quality of treatment. Among new works in the diagnosis of Alzheimer's disease, there are many of them analyzing the voice stream…

Machine Learning · Computer Science 2019-10-02 S. Soroush Haj Zargarbashi , Bagher Babaali

Epilepsy is a chronic neurological disorder characterized by recurrent unprovoked seizures, affects over 50 million people worldwide, and poses significant risks, including sudden unexpected death in epilepsy (SUDEP). Conventional unimodal…

Neural and Evolutionary Computing · Computer Science 2026-01-12 Ijaz Ahmad , Faizan Ahmad , Sunday Timothy Aboyeji , Yongtao Zhang , Peng Yang , Javed Ali Khan , Rab Nawaz , Baiying Lei

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

The aging population of the U.S. drives the prevalence of Alzheimer's disease. Brookmeyer et al. forecasts approximately 15 million Americans will have either clinical AD or mild cognitive impairment by 2060. In response to this urgent…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Long Chen , Liben Chen , Binfeng Xu , Wenxin Zhang , Narges Razavian

Alzheimer's disease (AD) has become one of the most significant health challenges in an aging society. The use of spoken language-based AD detection methods has gained prevalence due to their scalability due to their scalability. Based on…

Computation and Language · Computer Science 2024-12-02 Junan Li , Yunxiang Li , Yuren Wang , Xixin Wu , Helen Meng

Introduction- This paper mainly describes a way to detect with high accuracy patients with early-stage Alzheimer's disease (ES-AD) versus healthy control (HC) subjects, from datasets built with handwriting and drawing task records. Method-…

Machine Learning · Computer Science 2021-03-19 Alain Petrowski
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