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We consider problems of parameter estimation where design variables can be actively optimized to maximize information gain. To this end, we introduce JADAI, a framework that jointly amortizes Bayesian adaptive design and inference by…

Allocating patients to treatment arms during a trial based on the observed responses accumulated prior to the decision point, and sequential adaptation of this allocation,, could minimize the expected number of failures or maximize total…

Methodology · Statistics 2022-09-01 Zhongying Xu , Andriy I. Bandos , Tianzhou Ma , Lu Tang , Victor B. Talisa , Chung-Chou H. Chang

We propose an adaptive sequential framework for testing two simple hypotheses that analytically ensures finite exposure to the less effective treatment. Our proposed procedure employs a likelihood ratio-driven adaptive allocation rule,…

Statistics Theory · Mathematics 2025-11-26 Sampurna Kundu , Jayant Jha , Subir Kumar Bhandari

Bayesian Additive Regression Trees (BART) is a statistical sum of trees model. It can be considered a Bayesian version of machine learning tree ensemble methods where the individual trees are the base learners. However for data sets where…

We consider the problem of finding an optimal history-dependent routing strategy on a directed graph weighted by stochastic arc costs when the objective is to minimize the risk of spending more than a prescribed budget. To help mitigate the…

Data Structures and Algorithms · Computer Science 2016-02-23 Arthur Flajolet , Sebastien Blandin , Patrick Jaillet

Bayesian additive regression tree (BART) models have seen increased attention in recent years as a general-purpose nonparametric modeling technique. BART combines the flexibility of modern machine learning techniques with the principled…

Methodology · Statistics 2022-11-01 Antonio R. Linero

This work presents cost-effective low-rank techniques for designing robust adaptive beamforming (RAB) algorithms. The proposed algorithms are based on the exploitation of the cross-correlation between the array observation data and the…

Computational Engineering, Finance, and Science · Computer Science 2016-08-24 H. Ruan , R. C. de Lamare

Along with the successful deployment of deep neural networks in several application domains, the need to unravel the black-box nature of these networks has seen a significant increase recently. Several methods have been introduced to…

Machine Learning · Computer Science 2023-07-06 Adam Ivankay , Mattia Rigotti , Pascal Frossard

Critical infrastructure increasingly relies on interconnected cyber-physical systems whose security incidents can escalate rapidly into safety and operational failures. Existing decision-support approaches struggle to support real-time…

Cryptography and Security · Computer Science 2026-02-19 Shaofei Huang , Christopher M. Poskitt , Lwin Khin Shar

Randomized controlled trials (RCTs) frequently utilize covariate-adaptive randomization (CAR) (e.g., stratified block randomization) and commonly suffer from imperfect compliance. This paper studies the identification and inference for the…

Econometrics · Economics 2025-05-02 Federico A. Bugni , Mengsi Gao , Filip Obradovic , Amilcar Velez

This study investigates the applicability of 3D dose predictions from a model trained on one modality to a cross-modality automated planning workflow. Additionally, we explore the impact of integrating a multi-criteria optimizer on adapting…

Medical Physics · Physics 2024-02-26 Gregory Szalkowski , Xuanang Xu , Shiva Das , Pew-Thian Yap , Jun Lian

This article proposes a novel framework that integrates Bayesian Additive Regression Trees (BART) into a Factor-Augmented Vector Autoregressive (FAVAR) model to forecast macro-financial variables and examine asymmetries in the transmission…

Econometrics · Economics 2025-06-16 Sofia Velasco

Deterministic methods for motion planning guarantee safety amidst uncertainty in obstacle locations by trying to restrict the robot from operating in any possible location that an obstacle could be in. Unfortunately, this can result in…

Robotics · Computer Science 2023-06-21 Jinsun Liu , Challen Enninful Adu , Lucas Lymburner , Vishrut Kaushik , Lena Trang , Ram Vasudevan

Response-adaptive randomization (RAR) has been studied extensively in conventional, single-stage clinical trials, where it has been shown to yield ethical and statistical benefits, especially in trials with many treatment arms. However, RAR…

Methodology · Statistics 2024-01-09 Peter Norwood , Marie Davidian , Eric Laber

Motivated by the remarkable success of Bayesian additive regression trees (BART) in regression modelling, we propose a novel nonparametric Bayesian method, termed Functional BART (FBART), tailored specifically for function-on-scalar…

Methodology · Statistics 2025-06-03 Jiahao Cao , Shiyuan He , Bohai Zhang

Attribution maps are popular tools for explaining neural networks predictions. By assigning an importance value to each input dimension that represents its impact towards the outcome, they give an intuitive explanation of the decision…

Machine Learning · Computer Science 2022-03-09 Adam Ivankay , Ivan Girardi , Chiara Marchiori , Pascal Frossard

Calibrating Agent-Based Models (ABMs) is an important optimization problem for simulating the complex social systems, where the goal is to identify the optimal parameter of a given ABM by minimizing the discrepancy between the simulated…

Neural and Evolutionary Computing · Computer Science 2026-01-13 Boquan Jiang , Zhenhua Yang , Chenkai Wang , Muyao Zhong , Heping Fang , Peng Yang

Robust optimization provides a principled framework for decision-making under uncertainty, with broad applications in finance, engineering, and operations research. In portfolio optimization, uncertainty in expected returns and covariances…

Statistical Finance · Quantitative Finance 2025-10-15 Daniel Cunha Oliveira , Grover Guzman , Nick Firoozye

Integrative analysis of multiple datasets for estimating optimal individualized treatment rules (ITRs) can enhance decision efficiency. A central challenge is posterior shift, wherein the conditional distribution of potential outcomes given…

Machine Learning · Statistics 2026-03-09 Wenhai Cui , Wen Su , Xingqiu Zhao

In the era of precision medicine, genome-wide epigenetic modifications offer rich data that could inform risk prediction. However, these data are high-dimensional and exhibit complex dependence structures, which makes it difficult to…

Applications · Statistics 2026-05-25 Saurabh Bhandari , Parveen Bhatti , Brian C. -H. Chiu , Yuan Ji