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Related papers: RACS: Rapid Analysis of ChIP-Seq data for contig b…

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The development of AI-based methods to analyze radiology reports could lead to significant advances in medical diagnosis, from improving diagnostic accuracy to enhancing efficiency and reducing workload. However, the lack of…

Computation and Language · Computer Science 2025-08-14 Yuyan Ge , Kwan Ho Ryan Chan , Pablo Messina , René Vidal

Background Next Generation Sequencing (NGS) has dramatically enhanced our ability to sequence genomes, but not to assemble them. In practice, many published genome sequences remain in the state of a large set of contigs. Each contig…

Data Structures and Algorithms · Computer Science 2018-02-14 Antoine Limasset , Bastien Cazaux , Eric Rivals , Pierre Peterlongo

Reconfigurable Intelligent Surfaces (RISs) are becoming one of the fundamental building blocks of next-generation wireless communication systems. To that end, RIS phase configuration optimization is an important issue, where finding the…

Signal Processing · Electrical Eng. & Systems 2023-08-07 Samed Keşir , M. Yaser Yağan , İbrahim Hökelek , Ali Emre Pusane , Ali Görçin

Retrieval-Augmented Generation (RAG) has shown significant improvements in various natural language processing tasks by integrating the strengths of large language models (LLMs) and external knowledge databases. However, RAG introduces long…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-26 Chao Jin , Zili Zhang , Xuanlin Jiang , Fangyue Liu , Xin Liu , Xuanzhe Liu , Xin Jin

Three-Dimensional (3D) chromatin interactions, such as enhancer-promoter interactions (EPIs), loops, Topologically Associating Domains (TADs), and A/B compartments play critical roles in a wide range of cellular processes by regulating gene…

Genomics · Quantitative Biology 2024-03-07 Brydon P. G. Wall , My Nguyen , J. Chuck Harrell , Mikhail G. Dozmorov

Retrieval-Augmented Generation (RAG) has emerged as the dominant architectural pattern to operationalize Large Language Model (LLM) usage in Cyber Threat Intelligence (CTI) systems. However, this design is susceptible to poisoning attacks,…

Cryptography and Security · Computer Science 2025-12-17 Austin Jia , Avaneesh Ramesh , Zain Shamsi , Daniel Zhang , Alex Liu

This paper presents an accurate short-read mapper for next-generation sequencing data which is widely used in the 1000 Genomes Project, and human clinical and other species genome studies.

Genomics · Quantitative Biology 2015-06-17 Wan-Ping Lee , Michael Stromberg , Alistair Ward , Chip Stewart , Erik Garrison , Gabor T. Marth

In this paper we introduce Creek, a low-latency, eventually consistent replication scheme that also enables execution of strongly consistent operations (akin to ACID transactions). Operations can have arbitrary complex (but deterministic)…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-12-17 Tadeusz Kobus , Maciej Kokociński , Paweł T. Wojciechowski

Motivation: Machine learning based prediction of compound-protein interactions (CPIs) is important for drug design, screening and repurposing studies and can improve the efficiency and cost-effectiveness of wet lab assays. Despite the…

Quantitative Methods · Quantitative Biology 2022-02-02 Adiba Yaseen , Imran Amin , Naeem Akhter , Asa Ben-Hur , Fayyaz Minhas

Purpose: Coronary artery calcium (CAC) score, i.e. the amount of CAC quantified in CT, is a strong and independent predictor of coronary heart disease (CHD) events. However, CAC scoring suffers from limited interscan reproducibility, which…

Image and Video Processing · Electrical Eng. & Systems 2022-06-13 Sanne G. M. van Velzen , Bob D. de Vos , Julia M. H. Noothout , Helena M. Verkooijen , Max A. Viergever , Ivana Išgum

Metagenomics has led to significant advances in many fields. Metagenomic analysis commonly involves the key tasks of determining the species present in a sample and their relative abundances. These tasks require searching large metagenomic…

Near-tissue computing requires sensor-level processing of high-resolution images, essential for real-time biomedical diagnostics and surgical guidance. To address this need, we introduce a novel Capacitive Transimpedance Amplifier-based…

Image and Video Processing · Electrical Eng. & Systems 2025-03-24 Zihan Yin , Subhradip Chakraborty , Ankur Singh , Chengwei Zhou , Gourav Datta , Akhilesh Jaiswal

Accurate detection of colorectal cancer and early prevention heavily rely on precise polyp identification during gastrointestinal colonoscopy. Due to limited data, many current state-of-the-art deep learning methods for polyp segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-05-31 Ankush Gajanan Arudkar , Bernard J. E. Evans

The production of science-ready data from major solar telescopes requires expertise beyond that of the typical observer. This is a consequence of the increasing complexity of instruments and observing sequences, which require calibrations…

Solar and Stellar Astrophysics · Physics 2014-12-17 J. de la Cruz Rodríguez , M. Löfdahl , P. Sütterlin , T. Hillberg , L. Rouppe van der Voort

Analyzing medical data to find abnormalities is a time-consuming and costly task, particularly for rare abnormalities, requiring tremendous efforts from medical experts. Artificial intelligence has become a popular tool for the automatic…

Intrusion Detection and Prevention Systems (IDS/IPS) in large enterprises can generate hundreds of thousands of alerts per hour, overwhelming analysts with logs requiring rapidly evolving expertise. Conventional machine-learning detectors…

Cryptography and Security · Computer Science 2026-02-10 Francesco Blefari , Cristian Cosentino , Francesco Aurelio Pironti , Angelo Furfaro , Fabrizio Marozzo

Referring image segmentation (RIS) is a fundamental vision-language task that intends to segment a desired object from an image based on a given natural language expression. Due to the essentially distinct data properties between image and…

Computer Vision and Pattern Recognition · Computer Science 2024-02-15 Wenxuan Wang , Jing Liu , Xingjian He , Yisi Zhang , Chen Chen , Jiachen Shen , Yan Zhang , Jiangyun Li

Large biological datasets are being produced at a rapid pace and create substantial storage challenges, particularly in the domain of high-throughput sequencing (HTS). Most approaches currently used to store HTS data are either unable to…

Quantitative Methods · Quantitative Biology 2014-03-05 Fabien Campagne , Kevin C. Dorff , Nyasha Chambwe , James T. Robinson , Jill P. Mesirov , Thomas D. Wu

We present SynRXN, a unified benchmarking framework and open-data resource for computer-aided synthesis planning (CASP). SynRXN decomposes end-to-end synthesis planning into five task families, covering reaction rebalancing, atom-to-atom…

Machine Learning · Computer Science 2026-04-21 Tieu-Long Phan , Nhu-Ngoc Nguyen Song , Peter F. Stadler

A critical step of genome sequence analysis is the mapping of sequenced DNA fragments (i.e., reads) collected from an individual to a known linear reference genome sequence (i.e., sequence-to-sequence mapping). Recent works replace the…