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Understanding the morphological changes of primary neuronal cells induced by chemical compounds is essential for drug discovery. Using the data from a single high-throughput imaging assay, a classification model for predicting the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-02 Andrey Kormilitzin , Xinyu Yang , William H. Stone , Caroline Woffindale , Francesca Nicholls , Elena Ribe , Alejo Nevado-Holgado , Noel Buckley

An organism's ability to move freely is a fundamental behaviour in the animal kingdom. To understand animal locomotion requires a characterisation of the material properties, as well as the biomechanics and physiology. We present a…

Biological Physics · Physics 2017-02-17 Netta Cohen , Thomas Ranner

There is an increasing interest in the use of Deep Learning (DL) based methods as a supporting analytical framework in oncology. However, most direct applications of DL will deliver models with limited transparency and explainability, which…

Quantitative Methods · Quantitative Biology 2023-01-26 Magdalena Wysocka , Oskar Wysocki , Marie Zufferey , Dónal Landers , André Freitas

Understanding the per-layer learning dynamics of deep neural networks is of significant interest as it may provide insights into how neural networks learn and the potential for better training regimens. We investigate learning in Deep…

Machine Learning · Computer Science 2020-12-02 Ayush Manish Agrawal , Atharva Tendle , Harshvardhan Sikka , Sahib Singh , Amr Kayid

Deep learning (DL) allows computer models to learn, visualize, optimize, refine, and predict data. To understand its present state, examining the most recent advancements and applications of deep learning across various domains is…

Deep learning, a branch of machine learning, have been recently applied to high energy experimental and phenomenological studies. In this note we give a brief review on those applications using supervised deep learning. We first describe…

High Energy Physics - Phenomenology · Physics 2019-09-04 Murat Abdughani , Jie Ren , Lei Wu , Jin Min Yang , Jun Zhao

Deep neuroevolution and deep Reinforcement Learning have received a lot of attention in the last years. Some works have compared them, highlighting theirs pros and cons, but an emerging trend consists in combining them so as to benefit from…

Machine Learning · Computer Science 2022-06-14 Olivier Sigaud

From social networks to protein complexes to disease genomes to visual data, hypergraphs are everywhere. However, the scope of research studying deep learning on hypergraphs is still quite sparse and nascent, as there has not yet existed an…

Machine Learning · Computer Science 2019-10-08 Josh Payne

The serotonergic system modulates brain processes via functionally distinct subpopulations of neurons with heterogeneous properties, including their electrophysiological activity. In extracellular recordings, serotonergic neurons to be…

Neurons and Cognition · Quantitative Biology 2024-05-10 Daniele Corradetti , Alessandro Bernardi , Renato Corradetti

We propose a deep factorization model for typographic analysis that disentangles content from style. Specifically, a variational inference procedure factors each training glyph into the combination of a character-specific content embedding…

Machine Learning · Computer Science 2020-05-19 Nikita Srivatsan , Jonathan T. Barron , Dan Klein , Taylor Berg-Kirkpatrick

Neuro-Evolution is a field of study that has recently gained significantly increased traction in the deep learning community. It combines deep neural networks and evolutionary algorithms to improve and/or automate the construction of neural…

Neural and Evolutionary Computing · Computer Science 2020-10-05 Marijn van Knippenberg , Vlado Menkovski , Sergio Consoli

The last decade of machine learning has seen drastic increases in scale and capabilities. Deep neural networks (DNNs) are increasingly being deployed in the real world. However, they are difficult to analyze, raising concerns about using…

Machine Learning · Computer Science 2023-08-22 Tilman Räuker , Anson Ho , Stephen Casper , Dylan Hadfield-Menell

The success of deep learning has revolutionized many fields of research including areas of computer vision, text and speech processing. Enormous research efforts have led to numerous methods that are capable of efficiently analyzing data,…

Machine Learning · Computer Science 2020-07-20 Christoph Heindl

Deep learning, a branch of artificial intelligence, is a data-driven method that uses multiple layers of interconnected units or neurons to learn intricate patterns and representations directly from raw input data. Empowered by this…

Machine Learning · Computer Science 2025-07-28 Mohd Halim Mohd Noor , Ayokunle Olalekan Ige

Deep learning has proven to successfully learn variations in tissue and cell morphology. Training of such models typically relies on expensive manual annotations. Here we conjecture that spatially resolved gene expression, e.i., the…

Quantitative Methods · Quantitative Biology 2023-12-11 Axel Andersson , Gabriele Partel , Leslie Solorzano , Carolina Wählby

Given the inner complexity of the human nervous system, insight into the dynamics of brain activity can be gained from understanding smaller and simpler organisms, such as the nematode C. Elegans. The behavioural and structural biology of…

Neurons and Cognition · Quantitative Biology 2021-07-15 Gonçalo Mestre , Ruxandra Barbulescu , Arlindo L. Oliveira , L. Miguel Silveira

Machine learning can extract information from neural recordings, e.g., surface EEG, ECoG and {\mu}ECoG, and therefore plays an important role in many research and clinical applications. Deep learning with artificial neural networks has…

We propose a novel approach to enhance the discriminability of Convolutional Neural Networks (CNN). The key idea is to build a tree structure that could progressively learn fine-grained features to distinguish a subset of classes, by…

Computer Vision and Pattern Recognition · Computer Science 2017-09-25 Zhenhua Wang , Xingxing Wang , Gang Wang

Automatic human affect recognition is a key step towards more natural human-computer interaction. Recent trends include recognition in the wild using a fusion of audiovisual and physiological sensors, a challenging setting for conventional…

Machine Learning · Computer Science 2019-01-11 Philipp V. Rouast , Marc T. P. Adam , Raymond Chiong

Despite their increasing popularity and success in a variety of supervised learning problems, deep neural networks are extremely hard to interpret and debug: Given and already trained Deep Neural Net, and a set of test inputs, how can we…

Machine Learning · Computer Science 2018-06-07 Uday Singh Saini , Evangelos E. Papalexakis