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We investigate the merits of replication, and provide methods for optimal design (including replicates), with the goal of obtaining globally accurate emulation of noisy computer simulation experiments. We first show that replication can be…

Methodology · Statistics 2019-01-28 Mickael Binois , Jiangeng Huang , Robert B Gramacy , Mike Ludkovski

An active topic in the study of random constraint satisfaction problems (CSPs) is the geometry of the space of satisfying or almost satisfying assignments as the function of the density, for which a precise landscape of predictions has been…

Data Structures and Algorithms · Computer Science 2021-06-25 Jun-Ting Hsieh , Sidhanth Mohanty , Jeff Xu

Quantum algorithms are of great interest for their possible use in optimization problems. In particular, variational algorithms that use classical counterparts to optimize parameters hold promise for use in currently existing devices.…

Quantum Physics · Physics 2026-05-13 Bruno Oziel Fernandez , Rodrigo Bloot , Marcelo Moret

With the accelerating development of quantum technologies and their growing computational potential, quantum systems are being adapted for simulations and other critical tasks across diverse domains, making the reliability of the…

Software Engineering · Computer Science 2026-05-06 Maryse Ernzer , Seung Yeob Shin , Fabrizio Pastore , Domenico Bianculli

The Boolean satisfiability problem (SAT) is of central importance in both theory and practice. Yet, most provable guarantees for quantum algorithms rely exclusively on Grover-type methods that cap the possible advantage at only quadratic…

Quantum Physics · Physics 2025-11-14 Franz J. Schreiber , Maximilian J. Kramer , Alexander Nietner , Jens Eisert

We develop a novel iterative algorithm for locally optimal experimental design under constraints, like budget or performance constraints. It is an adaptive discretization algorithm. In every iteration, a discretized version of the…

Optimization and Control · Mathematics 2026-04-21 Jochen Schmid , Philipp Seufert , Jan Schwientek , Tobias Seidel , Karl-Heinz Küfer

Quantum circuit mapping is a crucial process in the quantum circuit compilation pipeline, facilitating the transformation of a logical quantum circuit into a list of instructions directly executable on a target quantum system. Recent…

Quantum Physics · Physics 2024-12-10 Di Yu , Kun Fang

As stakeholders and policy makers increasingly rely upon quantitative predictions from advanced computational models, a problem of fundamental importance is the quantification and reduction of uncertainties in both model inputs and output…

Numerical Analysis · Mathematics 2016-01-26 Scott Walsh

We design quantum circuits by using the standard cell approach borrowed from classical circuit design, which can speed-up the layout of circuits with a regular structure. Our standard cells are general and can be used for all types of…

Quantum Physics · Physics 2024-04-10 Evan E. Dobbs , Joseph S. Friedman , Alexandru Paler

We develop a set of algorithms to solve a broad class of Design of Experiment (DoE) problems efficiently. Specifically, we consider problems in which one must choose a subset of polymers to test in experiments such that the learning of the…

Quantitative Methods · Quantitative Biology 2024-08-06 Swagatam Mukhopadhyay

Several fundamental problems in science and engineering consist of global optimization tasks involving unknown high-dimensional (black-box) functions that map a set of controllable variables to the outcomes of an expensive experiment.…

Machine Learning · Computer Science 2023-09-15 Mohamed Aziz Bhouri , Michael Joly , Robert Yu , Soumalya Sarkar , Paris Perdikaris

Quantum algorithms to integrate nonlinear PDEs governing flow problems are challenging to discover but critical to enhancing the practical usefulness of quantum computing. We present here a near-optimal, robust, and end-to-end quantum…

The emergence of noisy intermediate-scale quantum (NISQ) computers has important consequences for cryptographic algorithms. It is theoretically well-established that key algorithms used in cybersecurity are vulnerable to quantum computers…

Cryptography and Security · Computer Science 2023-06-06 Sahay Harshvardhan , Sanil Jain , James E. McClure , Caleb McIrvin , Ngoc Quy Tran

Creative exploration is central to science, art and cognitive development. However, research on creative exploration is limited by a lack of high-resolution automated paradigms. To address this, we present such an automated paradigm, the…

Neurons and Cognition · Quantitative Biology 2017-06-06 Yuval Hart , Avraham E Mayo , Ruth Mayo , Liron Rozenkrantz , Avichai Tendler , Uri Alon , Lior Noy

We present a novel methodology for convex optimization algorithm design using ideas from electric RLC circuits. Given an optimization problem, the first stage of the methodology is to design an appropriate electric circuit whose…

Optimization and Control · Mathematics 2025-01-22 Stephen P. Boyd , Tetiana Parshakova , Ernest K. Ryu , Jaewook J. Suh

Quantum architecture search (QAS) is the process of automating architecture engineering of quantum circuits. It has been desired to construct a powerful and general QAS platform which can significantly accelerate current efforts to identify…

Quantum Physics · Physics 2022-11-15 Shi-Xin Zhang , Chang-Yu Hsieh , Shengyu Zhang , Hong Yao

Quantitative assessment of the uncertainties tainting the results of computer simulations is nowadays a major topic of interest in both industrial and scientific communities. One of the key issues in such studies is to get information about…

Statistics Theory · Mathematics 2023-12-05 Guillaume Damblin , Mathieu Couplet , Bertrand Iooss

In this paper, we propose a quantum computing oriented benchmark for combinatorial optimization. This benchmark, coined as QOPTLib, is composed of 40 instances equally distributed over four well-known problems: Traveling Salesman Problem,…

Quantum Physics · Physics 2024-04-25 Eneko Osaba , Esther Villar-Rodriguez

Optimizing quantum circuits is critical for enhancing computational speed and mitigating errors caused by quantum noise. Effective optimization must be achieved without compromising the correctness of the computations. This survey explores…

Quantum Physics · Physics 2025-01-03 Krishnageetha Karuppasamy , Varun Puram , Stevens Johnson , Johnson P Thomas

Bayesian experimental design is a technique that allows to efficiently select measurements to characterize a physical system by maximizing the expected information gain. Recent developments in deep neural networks and normalizing flows…

Quantum Physics · Physics 2023-06-27 Leopoldo Sarra , Florian Marquardt
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