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Neural circuits are able to perform computations under very diverse conditions and requirements. The required computations impose clear constraints on their fine-tuning: a rapid and maximally informative response to stimuli in general…

Neurons and Cognition · Quantitative Biology 2019-10-22 Jens Wilting , Jonas Dehning , Joao Pinheiro Neto , Lucas Rudelt , Michael Wibral , Johannes Zierenberg , Viola Priesemann

Artificial neural networks and computational neuroscience models have made tremendous progress, allowing computers to achieve impressive results in artificial intelligence (AI) applications, such as image recognition, natural language…

Neural and Evolutionary Computing · Computer Science 2019-11-05 Giacomo Indiveri , Yulia Sandamirskaya

Living organisms survive and multiply even though they have uncertain and incomplete information about their environment and imperfect models to predict the consequences of their actions. Bayesian models have been proposed to face this…

Emerging Technologies · Computer Science 2015-11-13 Jacques Droulez , David Colliaux , Audrey Houillon , Pierre Bessière

Networks are widely used to represent interaction pattern among the components in complex systems. Structures of real networks from differ- ent domains may vary quite significantly. Since there is an interplay be- tween network architecture…

Quantitative Methods · Quantitative Biology 2016-05-10 Krishanu Deyasi , Shashankaditya Upadhyay , Anirban Banerjee

For complex life to evolve, a sophisticated nervous system for handling its complexities was fundamental. The demand resulted in the emergence of brain's computational facility, the neuronal network. This facet of the brain is attested…

Neurons and Cognition · Quantitative Biology 2019-09-16 Jahan N. Schad

In view of ever-changing conditions both in the external world and in intrinsic brain states, maintaining the robustness of computations poses a challenge, adequate solutions to which we are only beginning to understand. At the level of…

Neurons and Cognition · Quantitative Biology 2022-03-29 Nelson Niemeyer , Jan-Hendrik Schleimer , Susanne Schreiber

Various neurophysiological and cognitive functions are based on transferring information between spiking neurons via a complex system of synaptic connections. In particular, the capacity of presynaptic inputs to influence the postsynaptic…

Neurons and Cognition · Quantitative Biology 2018-10-30 Y. Dabaghian

How extracellular electric fields, as generated endogenously or through transcranial brain stimulation, affect the dynamics of large neuronal populations is of great interest but not well understood. To study the collective dynamics of…

Neurons and Cognition · Quantitative Biology 2016-11-10 Florian Aspart , Josef Ladenbauer , Klaus Obermayer

Neuromorphic computing exploits the dynamical analogy between many physical systems and neuron biophysics. Superconductor systems, in particular, are excellent candidates for neuromorphic devices due to their capacity to operate in great…

Neurons and Cognition · Quantitative Biology 2022-05-24 Dimitrios Chalkiadakis , Johanne Hizanidis

A pressing scientific challenge is to understand how brains work. Of particular interest is the neocortex,the part of the brain that is especially large in humans, capable of handling a wide variety of tasks including visual, auditory,…

Neural and Evolutionary Computing · Computer Science 2016-09-03 Peter U. Diehl , Matthew Cook

In studies of the brain and the nervous system, extracellular signals - as measured by local field potentials (LFPs) or electroencephalography (EEG) - are of capital importance, as they allow to simultaneously obtain data from multiple…

Neurons and Cognition · Quantitative Biology 2019-06-10 Jurgis Pods

How neurons process their inputs crucially determines the dynamics of biological and artificial neural networks. In such neural and neural-like systems, synaptic input is typically considered to be merely transmitted linearly or sublinearly…

Biological Physics · Physics 2017-06-01 David Breuer , Marc Timme , Raoul-Martin Memmesheimer

The recent theoretical and experimental studies have revealed many details of signal propagation in nervous systems. In this paper an attempt is made to unify various mathematical models which describe the signal propagation in nerve…

Biological Physics · Physics 2016-01-11 Jüri Engelbrecht , Tanel Peets , Kert Tamm , Martin Laasmaa , Marko Vendelin

The extracellular matrix (ECM) is a highly complex structure through which biochemical and mechanical signals are transmitted. In processes of cell migration, the ECM also acts as a scaffold, providing structural support to cells as well as…

Synaptic plasticity dynamically shapes the connectivity of neural systems and is key to learning processes in the brain. To what extent the mechanisms of plasticity can be exploited to drive a neural network and make it perform some kind of…

Neurons and Cognition · Quantitative Biology 2024-12-03 Francesco Borra , Simona Cocco , Rémi Monasson

With conventional silicon-based computing approaching its physical and efficiency limits, biocomputing emerges as a promising alternative. This approach utilises biomaterials such as DNA and neurons as an interesting alternative to data…

Emerging Technologies · Computer Science 2024-08-15 Giulio Basso , Reinhold Scherer , Michael Taynnan Barros

While there has been a keen interest in studying computation at the edge of chaos for dynamical systems undergoing a phase transition, this has come under question for cellular automata. We show that for continuously deformed cellular…

Cellular Automata and Lattice Gases · Physics 2019-04-15 E. Estevez-Rams , D. Estevez-Moya , K. Garcia-Medina , R. Lora-Serrano

Neural communication operates on both fast synaptic transmission and slower, diffusive extrasynaptic signaling, yet how these two modes jointly organize brain function remains unclear. Here, using the complete synaptic and neuropeptidergic…

Neurons and Cognition · Quantitative Biology 2026-04-03 Giridhar Sunil , Habib Benali , Elkaïoum M. Moutuou

We investigate the ability of a genetic algorithm to design cellular automata that perform computations. The computational strategies of the resulting cellular automata can be understood using a framework in which ``particles'' embedded in…

adap-org · Physics 2015-06-30 James P. Crutchfield , Melanie Mitchell , Rajarshi Das

Biological phenomena differ significantly from physical phenomena. At the heart of this distinction is the fact that biological entities have computational abilities and thus they are inherently difficult to predict. This is the reason why…

Molecular Networks · Quantitative Biology 2009-09-29 Pau Fernandez , Ricard V. Sole