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Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the…

Artificial Intelligence · Computer Science 2026-05-26 Xiaoyang Fan , Yufan Cai , Zhe Hou , Jin Song Dong

Intent is defined for understanding spoken language in existing works. Both textual features and acoustic features involved in medical speech contain intent, which is important for symptomatic diagnosis. In this paper, we propose a medical…

Artificial Intelligence · Computer Science 2024-05-01 Jianzong Wang , Pengcheng Li , Xulong Zhang , Ning Cheng , Jing Xiao

We study a partially observable nonlinear stochastic system with unknown parameters, where the given time scales of the states and measurements may be distinct. The proposed setting is inspired by disease management, particularly leukemia.

Systems and Control · Electrical Eng. & Systems 2024-02-07 Margaret P. Chapman , Emily Jensen , Steven M. Chan , Laurent Lessard

Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can…

Quantitative Methods · Quantitative Biology 2020-04-13 Thomas Gaudelet , Noel Malod-Dognin , Jon Sanchez-Valle , Vera Pancaldi , Alfonso Valencia , Natasa Przulj

Unstructured data in Electronic Health Records (EHRs) often contains critical information -- complementary to imaging -- that could inform radiologists' diagnoses. But the large volume of notes often associated with patients together with…

Computation and Language · Computer Science 2024-06-12 Hiba Ahsan , Denis Jered McInerney , Jisoo Kim , Christopher Potter , Geoffrey Young , Silvio Amir , Byron C. Wallace

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Automated medical coding, an essential task for healthcare operation and delivery, makes unstructured data manageable by predicting medical codes from clinical documents. Recent advances in deep learning and natural language processing have…

Computation and Language · Computer Science 2024-05-15 Shaoxiong Ji , Wei Sun , Xiaobo Li , Hang Dong , Ara Taalas , Yijia Zhang , Honghan Wu , Esa Pitkänen , Pekka Marttinen

In medical diagnosis, physicians predict the state of a patient by checking measurements (features) obtained from a sequence of tests, e.g., blood test, urine test, followed by invasive tests. As tests are often costly, one would like to…

Machine Learning · Computer Science 2020-01-06 Arun Verma , Manjesh K. Hanawal , Nandyala Hemachandra

An extensive library of symptom inventories has been developed over time to measure clinical symptoms, but this variety has led to several long standing issues. Most notably, results drawn from different settings and studies are not…

Computation and Language · Computer Science 2023-09-12 Eamonn Kennedy , Shashank Vadlamani , Hannah M Lindsey , Kelly S Peterson , Kristen Dams OConnor , Kenton Murray , Ronak Agarwal , Houshang H Amiri , Raeda K Andersen , Talin Babikian , David A Baron , Erin D Bigler , Karen Caeyenberghs , Lisa Delano-Wood , Seth G Disner , Ekaterina Dobryakova , Blessen C Eapen , Rachel M Edelstein , Carrie Esopenko , Helen M Genova , Elbert Geuze , Naomi J Goodrich-Hunsaker , Jordan Grafman , Asta K Haberg , Cooper B Hodges , Kristen R Hoskinson , Elizabeth S Hovenden , Andrei Irimia , Neda Jahanshad , Ruchira M Jha , Finian Keleher , Kimbra Kenney , Inga K Koerte , Spencer W Liebel , Abigail Livny , Marianne Lovstad , Sarah L Martindale , Jeffrey E Max , Andrew R Mayer , Timothy B Meier , Deleene S Menefee , Abdalla Z Mohamed , Stefania Mondello , Martin M Monti , Rajendra A Morey , Virginia Newcombe , Mary R Newsome , Alexander Olsen , Nicholas J Pastorek , Mary Jo Pugh , Adeel Razi , Jacob E Resch , Jared A Rowland , Kelly Russell , Nicholas P Ryan , Randall S Scheibel , Adam T Schmidt , Gershon Spitz , Jaclyn A Stephens , Assaf Tal , Leah D Talbert , Maria Carmela Tartaglia , Brian A Taylor , Sophia I Thomopoulos , Maya Troyanskaya , Eve M Valera , Harm Jan van der Horn , John D Van Horn , Ragini Verma , Benjamin SC Wade , Willian SC Walker , Ashley L Ware , J Kent Werner , Keith Owen Yeates , Ross D Zafonte , Michael M Zeineh , Brandon Zielinski , Paul M Thompson , Frank G Hillary , David F Tate , Elisabeth A Wilde , Emily L Dennis

We examine a probabilistic model for the diagnosis of multiple diseases. In the model, diseases and findings are represented as binary variables. Also, diseases are marginally independent, features are conditionally independent given…

Artificial Intelligence · Computer Science 2022-12-07 David Heckerman

Extracting information from unstructured text documents is a demanding task, since these documents can have a broad variety of different layouts and a non-trivial reading order, like it is the case for multi-column documents or nested…

Artificial Intelligence · Computer Science 2022-02-08 Matthias Engelbach , Dennis Klau , Jens Drawehn , Maximilien Kintz

Despite the overwhelming quantity of health information that is available online today, finding reliable and trustworthy information is still challenging, even when advanced recommender systems are used. To tackle this challenge and improve…

Computers and Society · Computer Science 2019-01-08 Prakruthi Karuna , Hemant Purohit , Vivian Motti

Accurate healthcare prediction is essential for improving patient outcomes. Existing work primarily leverages advanced frameworks like attention or graph networks to capture the intricate collaborative (CO) signals in electronic health…

Machine Learning · Computer Science 2025-04-02 Chuang Zhao , Hui Tang , Jiheng Zhang , Xiaomeng Li

Automatic extraction of clinical concepts is an essential step for turning the unstructured data within a clinical note into structured and actionable information. In this work, we propose a clinical concept extraction model for automatic…

Computation and Language · Computer Science 2018-11-28 Henghui Zhu , Ioannis Ch. Paschalidis , Amir Tahmasebi

In the field of health-care and bio-medical research, understanding the relationship between the symptoms of diseases is crucial for early diagnosis and determining hidden relationships between diseases. The study aimed to understand the…

Artificial Intelligence · Computer Science 2023-02-24 Zolzaya Dashdorj , Stanislav Grigorev , Munguntsatsral Dovdondash

Most of the existing medication recommendation models are predicted with only structured data such as medical codes, with the remaining other large amount of unstructured or semi-structured data underutilization. To increase the utilization…

Computation and Language · Computer Science 2024-07-16 Yu-Tzu Lee

Objective: Automatic text summarization tools can help users in the biomedical domain to access information efficiently from a large volume of scientific literature and other sources of text documents. In this paper, we propose a…

Information Retrieval · Computer Science 2018-11-26 Milad Moradi , Nasser Ghadiri

This paper proposes a knowledge-enhanced disease diagnosis method based on a prompt learning framework. The method retrieves structured knowledge from external knowledge graphs related to clinical cases, encodes it, and injects it into the…

Computation and Language · Computer Science 2024-09-17 Zhang Zheng

Accurate and explainable health event predictions are becoming crucial for healthcare providers to develop care plans for patients. The availability of electronic health records (EHR) has enabled machine learning advances in providing these…

Machine Learning · Computer Science 2021-05-18 Chang Lu , Chandan K. Reddy , Prithwish Chakraborty , Samantha Kleinberg , Yue Ning

Word embeddings are a popular way to improve downstream performances in contemporary language modeling. However, the underlying geometric structure of the embedding space is not well understood. We present a series of explorations using…

Computation and Language · Computer Science 2020-09-17 Hongwei , Zhou , Oskar Elek , Pranav Anand , Angus G. Forbes