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In this perspective, we examine three key aspects of an end-to-end pipeline for realistic cellular simulations: reconstruction and segmentation of cellular structures; generation of cellular structures; and mesh generation, simulation, and…

System-level design, once the province of board designers, has now become a central concern for chip designers. Because chip design is a less forgiving design medium -- design cycles are longer and mistakes are harder to correct --…

Hardware Architecture · Computer Science 2025-07-15 Shuvra S. Bhattacharyya , Marilyn Wolf

Build-time configuration and environment assumptions are hampering progress and usability in scientific software. That which would be utterly unacceptable in non-scientific software somehow passes for the norm in scientific packages. The…

Software Engineering · Computer Science 2014-07-11 Jed Brown , Matthew G. Knepley , Barry F. Smith

Simulation is essential to validate autonomous driving systems. However, a simple simulation, even for an extremely high number of simulated miles or hours, is not sufficient. We need well-founded criteria showing that simulation does…

Software Engineering · Computer Science 2023-01-24 Changwen Li , Joseph Sifakis , Qiang Wang , Rongjie Yan , Jian Zhang

This work discusses the benefits of having multiple simulated environments with different degrees of realism for the development of algorithms in scenarios populated by autonomous nodes capable of communication and mobility. This approach…

Networking and Internet Architecture · Computer Science 2024-03-25 Thiago de Souza Lamenza , Josef Kamysek , Bruno Jose Olivieri de Souza , Markus Endler

Safety is one of the most critical factors in robotics, especially when robots have to collaborate with people in a~shared environment. Testing the physical systems, however, must focus on much more than just software. One of the common…

Robotics · Computer Science 2021-04-02 Krystian Chachuła , Maciej Stefańczyk

The designers pre-occupation to reduce energy consumption and to achieve better thermal ambience levels, has favoured the setting up of numerous building thermal dynamic simulation programs. The progress in the modelling of phenomenas and…

Computational Engineering, Finance, and Science · Computer Science 2012-12-26 Harry Boyer , François Garde , Jean Claude Gatina , Jean Brau

The past few years have witnessed the concrete and fast spreading of quantum technologies for practical computation and simulation. In particular, quantum computing platforms based on either trapped ions or superconducting qubits have…

Quantum Physics · Physics 2020-04-21 Francesco Tacchino , Alessandro Chiesa , Stefano Carretta , Dario Gerace

The concept of quantum computing has inspired a whole new generation of scientists, including physicists, engineers, and computer scientists, to fundamentally change the landscape of information technology. With experimental demonstrations…

With the rapid advancement of information technology, the complexity of applications continues to increase, and the cybersecurity challenges we face are also escalating. This paper aims to investigate the methods and practices of system…

Cryptography and Security · Computer Science 2026-02-02 Chunyi Zhang , Jin Zeng , Xiaoqi Li

Major challenges for the transition of power systems do not only tackle power electronics but also communication technology, power market economy and user acceptance studies. Simulation is an important research method therein, as it helps…

Systems and Control · Computer Science 2018-07-03 Manfred Pöchacker , Anita Sobe , Wilfried Elmenreich

Continual learning is essential for all real-world applications, as frozen pre-trained models cannot effectively deal with non-stationary data distributions. The purpose of this study is to review the state-of-the-art methods that allow…

Machine Learning · Computer Science 2022-02-28 Khadija Shaheen , Muhammad Abdullah Hanif , Osman Hasan , Muhammad Shafique

Large Language Models (LLMs) are becoming ubiquitous to create intelligent virtual assistants that assist users in interacting with a system, as exemplified in marketing. Although LLMs have been discussed in Modeling & Simulation (M&S), the…

Human-Computer Interaction · Computer Science 2024-09-25 Philippe J. Giabbanelli , Jose J. Padilla , Ameeta Agrawal

In most of the cases, the experimental study of Nanotechnology involves high cost for Laboratory set-up and the experimentation processes were also slow. So, one cannot rely on experimental nanotechnology alone. As such, the Computer-Based…

Emerging Technologies · Computer Science 2011-09-09 Tamal Sarkar , Samir Chandra Das , Ardhendu Mandal

Industrial human-robot collaborative systems must be validated thoroughly with regard to safety. The sooner potential hazards for workers can be exposed, the less costly is the implementation of necessary changes. Due to the complexity of…

Robotics · Computer Science 2021-11-30 Tom P. Huck , Christoph Ledermann , Torsten Kröger

Surgeons must accomplish complex technical and intellectual tasks that can generate unexpected and serious challenges with little or no room for error. In the last decade, computer simulations have played an increasing role in surgical…

Human-Computer Interaction · Computer Science 2019-03-12 Felix G. Hamza-Lup , Crenguta M. Bogdan , Dorin M. Popovici , Ovidiu D. Costea

This paper presents main concepts and issues concerned with the simulation of Internet of Things (IoT). The heterogeneity of possible scenarios, arising from the massive deployment of an enormous amount of sensors and devices, imposes the…

Networking and Internet Architecture · Computer Science 2016-09-27 Gabriele D'Angelo , Stefano Ferretti , Vittorio Ghini

Synthetic data and simulators have the potential to markedly improve the performance and robustness of recommendation systems. These approaches have already had a beneficial impact in other machine-learning driven fields. We identify and…

Information Retrieval · Computer Science 2021-12-22 Adam Lesnikowski , Gabriel de Souza Pereira Moreira , Sara Rabhi , Karl Byleen-Higley

In the effort to develop useful quantum computers simulating quantum machines with conventional computing resources is a key capability. Such simulations will always face limits preventing the emulation of quantum computers of substantial…

Quantum Physics · Physics 2023-02-20 Xiaosi Xu , Simon Benjamin , Jinzhao Sun , Xiao Yuan , Pan Zhang

Algorithms for continuous optimization problems have a rich history of design and innovation over the past several decades, in which mathematical analysis of their convergence and complexity properties plays a central role. Besides their…

Optimization and Control · Mathematics 2025-12-03 Stephen J. Wright