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In recent years, deep learning has successfully been applied to automate a wide variety of tasks in diagnostic histopathology. However, fast and reliable localization of small-scale regions-of-interest (ROI) has remained a key challenge, as…

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

In modern cancer diagnostics, Whole Slide Imaging (WSI) is widely used to digitize tissue specimens for detailed, high-resolution examination; however, other diagnostic approaches, such as liquid biopsy and molecular testing, are also…

Tumor proliferation is an important biomarker indicative of the prognosis of breast cancer patients. Assessment of tumor proliferation in a clinical setting is highly subjective and labor-intensive task. Previous efforts to automate tumor…

Representation learning for Whole Slide Images (WSIs) is pivotal in developing image-based systems to achieve higher precision in diagnostic pathology. We propose a two-stage framework for WSI representation learning. We sample relevant…

Whole Slide Images (WSIs) are giga-pixel in scale and are typically partitioned into small instances in WSI classification pipelines for computational feasibility. However, obtaining extensive instance level annotations is costly, making…

We propose a modular framework for predicting cancer specific survival directly from whole slide pathology images (WSIs). The framework consists of four key stages designed to capture prognostic and morphological heterogeneity. First, a…

Encoding whole slide images (WSI) as graphs is well motivated since it makes it possible for the gigapixel resolution WSI to be represented in its entirety for the purpose of graph learning. To this end, WSIs can be broken into smaller…

The rapid advancement in high-resolution satellite remote sensing data acquisition, particularly those achieving submeter precision, has uncovered the potential for detailed extraction of surface architectural features. However, the…

That datasets that are used in todays research are especially vast in the medical field. Different types of medical images such as X-rays, MRI, CT scan etc. take up large amounts of space. This volume of data introduces challenges like…

Radiologists interpret mammography exams by jointly analyzing all four views, as correlations among them are crucial for accurate diagnosis. Recent methods employ dedicated fusion blocks to capture such dependencies, but these are often…

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…

We present a unified framework to predict tumor proliferation scores from breast histopathology whole slide images. Our system offers a fully automated solution to predicting both a molecular data-based, and a mitosis counting-based tumor…

Convolutional Neural Network (CNN) models have become the state-of-the-art for most computer vision tasks with natural images. However, these are not best suited for multi-gigapixel resolution Whole Slide Images (WSIs) of histology slides…

Mitotic activity is an important feature for grading several cancer types. Counting mitotic figures (MFs) is a time-consuming, laborious task prone to inter-observer variation. Inaccurate recognition of MFs can lead to incorrect grading and…

Computer assisted diagnosis in digital pathology is becoming ubiquitous as it can provide more efficient and objective healthcare diagnostics. Recent advances have shown that the convolutional Neural Network (CNN) architectures, a…

Background and objective: Employing deep learning models in critical domains such as medical imaging poses challenges associated with the limited availability of training data. We present a strategy for improving the performance and…

This study focuses on the classification of cancerous and healthy slices from multimodal lung images. The data used in the research comprises Computed Tomography (CT) and Positron Emission Tomography (PET) images. The proposed strategy…

Digital pathology provides an excellent opportunity for applying fully convolutional networks (FCNs) to tasks, such as semantic segmentation of whole slide images (WSIs). However, standard FCNs face challenges with respect to…

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…