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Policy evaluation in empirical microeconomics has been focusing on estimating the average treatment effect and more recently the heterogeneous treatment effects, often relying on the unconfoundedness assumption. We propose a method based on…

Econometrics · Economics 2023-06-06 Wei Tian

For randomized trials that use text as an outcome, traditional approaches for assessing treatment impact require that each document first be manually coded for constructs of interest by trained human raters. This process, the current…

Methodology · Statistics 2024-08-05 Reagan Mozer , Luke Miratrix

The use of machine learning to guide clinical decision making has the potential to worsen existing health disparities. Several recent works frame the problem as that of algorithmic fairness, a framework that has attracted considerable…

Machine Learning · Statistics 2021-06-16 Stephen R. Pfohl , Agata Foryciarz , Nigam H. Shah

Automated voice calls are an effective method of delivering maternal and child health information to mothers in underserved communities. One method to fight dwindling listenership is through an intervention in which health workers make live…

Human-Computer Interaction · Computer Science 2024-07-18 Arpan Dasgupta , Niclas Boehmer , Neha Madhiwalla , Aparna Hedge , Bryan Wilder , Milind Tambe , Aparna Taneja

Despite the massive costs and widespread harms of substance use, most individuals with substance use disorders (SUDs) receive no treatment at all. Digital therapeutics platforms are an emerging low-cost and low-barrier means of extending…

Systems and Control · Electrical Eng. & Systems 2025-04-03 Eric Pulick , Yonatan Mintz

Health management has become a primary problem as new kinds of diseases and complex symptoms are introduced to a rapidly growing modern society. Building a better and smarter healthcare infrastructure is one of the ultimate goals of a smart…

Machine Learning · Computer Science 2025-03-24 Chu Myaet Thwal , Kyi Thar , Ye Lin Tun , Choong Seon Hong

Integrating information from multiple data sources can enable more precise, timely, and generalizable decisions. However, it is challenging to make valid causal inferences using observational data from multiple data sources. For example, in…

Methodology · Statistics 2023-02-08 Larry Han , Yige Li , Bijan A. Niknam , Jose R. Zubizarreta

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

Machine Learning · Computer Science 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

Artificial intelligence (AI) systems increasingly achieve expert-level predictive accuracy in healthcare, yet improvements in model performance often fail to produce corresponding gains in patient outcomes. We term this disconnect the…

Artificial Intelligence · Computer Science 2026-01-13 Rifa Ferzana

Trauma mortality results from a multitude of non-linear dependent risk factors including patient demographics, injury characteristics, medical care provided, and characteristics of medical facilities; yet traditional approach attempted to…

Machine Learning · Computer Science 2020-09-11 Joshua D. Cardosi , Herman Shen , Jonathan I. Groner , Megan Armstrong , Henry Xiang

We consider the estimation of heterogeneous treatment effects with arbitrary machine learning methods in the presence of unobserved confounders with the aid of a valid instrument. Such settings arise in A/B tests with an intent-to-treat…

Econometrics · Economics 2019-06-07 Vasilis Syrgkanis , Victor Lei , Miruna Oprescu , Maggie Hei , Keith Battocchi , Greg Lewis

Background: Clinical prediction models for a health condition are commonly evaluated regarding performance for a population, although decisions are made for individuals. The classic view relates uncertainty in risk estimates for individuals…

Randomized controlled trials play an important role in how Internet companies predict the impact of policy decisions and product changes. In these `digital experiments', different units (people, devices, products) respond differently to the…

Applications · Statistics 2015-12-21 Matt Taddy , Matt Gardner , Liyun Chen , David Draper

BACKGROUND: As databases grow larger, it becomes harder to fully control their collection, and they frequently come with missing values: incomplete observations. These large databases are well suited to train machine-learning models, for…

Machine Learning · Computer Science 2022-02-23 Alexandre Perez-Lebel , Gaël Varoquaux , Marine Le Morvan , Julie Josse , Jean-Baptiste Poline

Background: Hypertensive kidney disease (HKD) patients in intensive care units (ICUs) face high short-term mortality, but tailored risk prediction tools are lacking. Early identification of high-risk individuals is crucial for clinical…

Machine Learning · Computer Science 2025-07-28 Yong Si , Junyi Fan , Li Sun , Shuheng Chen , Minoo Ahmadi , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui

Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…

Machine Learning · Computer Science 2025-01-03 Arseniy Shumilov , Yueting Zhu , Negin Ashrafi , Armin Abdollahi , Greg Placencia , Kamiar Alaei , Maryam Pishgar

Unattended scheduled appointments, defined as patient no-shows, adversely affect both healthcare providers and patients' health, disrupting the continuity of care, operational efficiency, and the efficient allocation of medical resources.…

Machine Learning · Computer Science 2026-01-21 Ninda Nurseha Amalina , Heungjo An

Objective: This paper introduces a patient simulator for scalable, automated evaluation of healthcare conversational agents, generating realistic, controllable interactions that systematically vary across medical, linguistic, and behavioral…

Considerations regarding clinical effectiveness and cost are essential in comparing the overall value of two treatments. There has been growing interest in methodology to integrate cost and effectiveness measures in order to inform policy…

Methodology · Statistics 2019-12-04 Andrew J. Spieker , Nicholas Illenberger , Jason A. Roy , Nandita Mitra
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