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Adherence can be defined as "the extent to which patients take their medications as prescribed by their healthcare providers"[Osterberg and Blaschke, 2005]. World Health Organization's reports point out that, in developed countries, only…

Machine Learning · Computer Science 2018-11-30 Thomas Janssoone , Clémence Bic , Dorra Kanoun , Pierre Hornus , Pierre Rinder

Pragmatic trials increasingly define outcomes using real-world data such as electronic health records, where assessments are collected during routine care rather than at fixed timepoints. Consequently, these uncontrolled assessments may be…

This research presents an examination of categorizing the severity states of patients based on their electronic health records during a certain time range using multiple machine learning and deep learning approaches. The suggested method…

Machine Learning · Computer Science 2022-09-30 A. N. M. Sajedul Alam , Rimi Reza , Asir Abrar , Tanvir Ahmed , Salsabil Ahmed , Shihab Sharar , Annajiat Alim Rasel

We address the personalized policy learning problem using longitudinal mobile health application usage data. Personalized policy represents a paradigm shift from developing a single policy that may prescribe personalized decisions by…

Methodology · Statistics 2020-01-13 Xinyu Hu , Min Qian , Bin Cheng , Ying Kuen Cheung

LLM-based agents have demonstrated strong potential for autonomous machine learning, yet their applicability to health data remains limited. Existing systems often struggle to generalize across heterogeneous health data modalities, rely…

Artificial Intelligence · Computer Science 2026-02-03 Tong Xia , Weibin Li , Gang Liu , Yong Li

Due to rapidly rising healthcare costs worldwide, there is significant interest in controlling them. An important aspect concerns price transparency, as preliminary efforts have demonstrated that patients will shop for lower costs, driving…

Machine Learning · Computer Science 2023-04-06 A. Ravishankar Rao , Subrata Garai , Soumyabrata Dey , Hang Peng

Precision oncology aims to prescribe the optimal cancer treatment to the right patients, maximizing therapeutic benefits. However, identifying patient subgroups that may benefit more from experimental cancer treatments based on randomized…

Methodology · Statistics 2026-01-06 Xingyu Li , Qing Liu , Tony Jiang , Hong Amy Xia , Peng Wei , Brian P. Hobbs

Problem: How can we design patient cost prediction models that effectively address the challenges of heterogeneity in administrative claims (AC) data to ensure accurate, fair, and generalizable predictions, especially for high-need (HN)…

Machine Learning · Computer Science 2025-02-19 Mohammad Amin Morid , Olivia R. Liu Sheng

Deep Learning based models are currently dominating most state-of-the-art solutions for disease prediction. Existing works employ RNNs along with multiple levels of attention mechanisms to provide interpretability. These deep learning…

Machine Learning · Statistics 2022-06-01 Subhadip Maji , Raghav Bali , Sree Harsha Ankem , Kishore V Ayyadevara

To effect behavior change a successful algorithm must make high-quality decisions in real-time. For example, a mobile health (mHealth) application designed to increase physical activity must make contextually relevant suggestions to…

Machine Learning · Statistics 2020-03-31 Marianne Menictas , Sabina Tomkins , Susan A Murphy

There is a need of ensuring machine learning models that are interpretable. Higher interpretability of the model means easier comprehension and explanation of future predictions for end-users. Further, interpretable machine learning models…

Machine Learning · Computer Science 2020-08-17 Gregor Stiglic , Primoz Kocbek , Nino Fijacko , Marinka Zitnik , Katrien Verbert , Leona Cilar

Accurate estimation of healthcare costs is crucial for healthcare systems to plan and effectively negotiate with insurance companies regarding the coverage of patient-care costs. Greater accuracy in estimating healthcare costs would provide…

Machine Learning · Computer Science 2022-06-02 Alex Taylor , Ross Kleiman , Scott Hebbring , Peggy Peissig , David Page

Disease models are used to examine the likely impact of therapies, interventions and public policy changes. Ensuring that these are well calibrated on the basis of available data and that the uncertainty in their projections is properly…

Computation · Statistics 2025-01-24 Daria Semochkina , Cathal Walsh

A growing body of work uses the paradigm of algorithmic fairness to frame the development of techniques to anticipate and proactively mitigate the introduction or exacerbation of health inequities that may follow from the use of…

Machine Learning · Statistics 2022-02-07 Stephen R. Pfohl , Yizhe Xu , Agata Foryciarz , Nikolaos Ignatiadis , Julian Genkins , Nigam H. Shah

This study proposes a novel, integrative framework for patient-centered data science in the digital health era. We developed a multidimensional model that combines traditional clinical data with patient-reported outcomes, social…

Machine Learning · Computer Science 2024-08-07 Mohsen Amoei , Dan Poenaru

This study presents a machine learning-based framework for heart disease prediction using the heart-disease dataset, comprising 303 samples with 14 features. The methodology involves data preprocessing, model training, and evaluation using…

Machine Learning · Computer Science 2025-05-16 Ali Azimi Lamir , Shiva Razzagzadeh , Zeynab Rezaei

Clinical researchers often select among and evaluate risk prediction models using standard machine learning metrics based on confusion matrices. However, if these models are used to allocate interventions to patients, standard metrics…

Machine Learning · Statistics 2020-06-03 Alejandro Schuler , Aashish Bhardwaj , Vincent Liu

Background Predicting mortality and resource utilization from electronic health records (EHRs) is challenging yet crucial for optimizing patient outcomes and managing costs in intensive care unit (ICU). Existing approaches predominantly…

Computation and Language · Computer Science 2025-08-29 Yucheng Ruan , Xiang Lan , Daniel J. Tan , Hairil Rizal Abdullah , Mengling Feng

This study reveals the important role of prevention care and medication adherence in reducing hospitalizations. By using a structured dataset of 1,171 patients, four machine learning models Logistic Regression, Gradient Boosting, Random…

Machine Learning · Computer Science 2025-04-11 Yixin Zhang , Yisong Chen

Insurance companies must manage millions of claims per year. While most of these claims are non-fraudulent, fraud detection is core for insurance companies. The ultimate goal is a predictive model to single out the fraudulent claims and pay…

Machine Learning · Computer Science 2018-09-03 Leander Löw , Martin Spindler , Eike Brechmann