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Macromolecules change their shape (conformation) in the process of carrying out their functions. The imaging by cryo-electron microscopy of rapidly-frozen, individual copies of macromolecules (single particles) is a powerful and general…

Biomolecules · Quantitative Biology 2022-11-22 Bogdan Toader , Fred J. Sigworth , Roy R. Lederman

Cryo-electron microscopy is a revolutionary technique that can provide 3D density maps at near-atomic resolution. However, map validation is still an open issue in the field. Despite several efforts from the community, it is possible to…

Biological Physics · Physics 2019-08-06 Sebastian Ortiz , Luka Stanisic , Boris A Rodriguez , Markus Rampp , Gerhard Hummer , Pilar Cossio

We propose a multi-layer graphene-based device in which storage and release of atomic hydrogen is obtained by exploiting and controlling the corrugation of the layers. The proposal is based on density-functional simulations of hydrogen…

Mesoscale and Nanoscale Physics · Physics 2011-01-07 Valentina Tozzini , Vittorio Pellegrini

Vision processing on traditional architectures is inefficient due to energy-expensive off-chip data movement. Many researchers advocate pushing processing close to the sensor to substantially reduce data movement. However, continuous…

Signal Processing · Electrical Eng. & Systems 2020-01-07 Venkatesh Kodukula , Saad Katrawala , Britton Jones , Carole-Jean Wu , Robert LiKamWa

The phenomenon of cell sorting/segregation, by which cells organise spatially into clusters of specific cell type or function, is essential for tissue morphogenesis. This self-organization process involves an interplay between mechanical,…

Biological Physics · Physics 2025-03-19 Marius Bothe , Eloise Lardet , Alexei Poliakov , Gunnar Pruessner , Thibault Bertrand , Ignacio Bordeu

We describe a 3D percolation-type approach to modeling of the processes of aging and certain other properties of tissues analyzed as systems consisting of interacting cells. Lattice sites are designated as regular (healthy) cells, senescent…

Statistical Mechanics · Physics 2016-07-12 Vyacheslav Gorshkov , Vladimir Privman , Sergiy Libert

Cold piezoelectric plasma (CPP) is a novel approach in cancer therapy, enabling the development of portable treatment devices capable of triggering cancer cell death. While its effectiveness remains underexplored, this research focuses on…

Enhancing cryogenic electron microscopy (cryo-EM) 3D density maps at intermediate resolution (4-8 {\AA}) is crucial in protein structure determination. Recent advances in deep learning have led to the development of automated approaches for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-16 Chenwei Zhang , Khanh Dao Duc

Investigations of free-standing liquid films enjoy an increasing popularity due to their relevance for many fundamental and applied scientific problems. They constitute soap bubbles and foams, serve as membranes for gas transport or as…

Porous and flexible actuating materials are important in the development of smart systems. We report here a facile method to prepare scalable, flexible actuating porous membranes based on a poly(ionic liquid)-modified tissue paper. The…

Applied Physics · Physics 2017-05-23 Huijuan Lin , Jiang Gong , Han Miao , Ryan Guterman , Haojie Song , Qiang Zhao , John W. C. Dunlop , Jiayin Yuan

3D stacked technology has emerged as an effective mechanism to overcome physical limits and communication delays found in 2D integration. However, 3D technology also presents several drawbacks that prevent its smooth application. Two of the…

Hardware Architecture · Computer Science 2024-02-23 David Cuesta , José L. Risco-Martín , José L. Ayala , J. Ignacio Hidalgo

Scaling down miniature rotorcraft and flapping-wing flyers to sub-centimeter dimensions is challenging due to complex electronics requirements, manufacturing limitations, and the increase in viscous damping at low Reynolds numbers.…

Li-ion batteries are crucial components for progress in mobile communications and transport technologies. However, Li-ion batteries suffer from strong self-heating, which limits their life-time and creates reliability and environmental…

Lithium-ion batteries are widely used in electric vehicles and grid energy storage systems. Compared to cylindrical batteries, prismatic cells are the primary choice because of their advantage for dense packing. However, thermal runaway and…

Applied Physics · Physics 2024-07-23 Mehdi V. Bozorg , Juan F. Torres

Focused electron beam induced deposition (FEBID) is a direct write technique for depositing materials on a support substrate akin to 3D printing with an electron beam (e-beam). Opportunities exist for merging this existing technique with…

Materials Science · Physics 2023-07-13 Ondrej Dyck , Andrew R. Lupini , Philip D. Rack , Jason Fowlkes , Stephen Jesse

Thermal ionization is a critical process at temperatures T > 10 3 K, particularly during star formation. An increase in ionization leads to a decrease in nonideal magnetohydrodynamics (MHD) resistivities, which has a significant impact on…

Solar and Stellar Astrophysics · Physics 2022-10-05 Pierre Marchand , Vincent Guillet , Ugo Lebreuilly , Mordecai-Mark Mac Low

Thermalized elastic membranes without distant self-avoidance are believed to undergo a crumpling transition when the microscopic bending stiffness is comparable to $kT$, the scale of thermal fluctuations. Most potential physical…

Soft Condensed Matter · Physics 2017-11-16 D. Yllanes , S. S. Bhabesh , D. R. Nelson , M. J. Bowick

This paper introduces a new method of paper circuit fabrication that overcomes design barriers and increases flexibility in circuit design. Conventional circuit boards rely on thin traces, which limits the complexity and accuracy when…

Human-Computer Interaction · Computer Science 2024-04-12 Ruhan Yang , Krithik Ranjan , Ellen Yi-Luen Do

Vertical graphene nanosheets (VGNs) are the material of choice for next-generation electronic device applications. The growing demand for flexible devices in electronic industry brings in restriction on growth temperature of the material of…

Materials Science · Physics 2022-02-02 Gopinath Sahoo , Subrata Ghosh , S. R. Polaki , Tom Mathews , M. Kamruddin

In this work, a coarse-graining method previously proposed by the authors in a companion paper based on solving diffusion equations is applied to CFD-DEM simulations, where coarse graining is used to obtain solid volume fraction, particle…

Computational Physics · Physics 2015-01-07 Rui Sun , Heng Xiao