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Photoacoustic imaging (PAI) represents an innovative biomedical imaging modality that harnesses the advantages of optical resolution and acoustic penetration depth while ensuring enhanced safety. Despite its promising potential across a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lei Wang , Weiming Zeng , Kai Long , Hongyu Chen , Rongfeng Lan , Li Liu , Wai Ting Siok , Nizhuan Wang

Optical scattering presents a major obstacle to high resolution imaging in biological tissue and other turbid media. Conventional photoacoustic imaging can partially overcome this obstacle, enabling imaging of optical absorption in the…

Photoacoustic (PA) imaging combines the high optical absorption contrast of optical imaging with the deep tissue penetration of ultrasound detection, offering great potential for functional imaging and disease diagnosis. However, current PA…

Optics · Physics 2026-01-29 Daohuai Jiang , Xuanxuan Ye , Hengrong Lan , Xianzeng Zhang , Fei Gao

In Fourier ptychography, multiple low resolution images are captured and subsequently combined computationally into a high-resolution, large-field of view micrograph. A theoretical image-formation model based on the assumption of plane-wave…

Optics · Physics 2022-06-22 Tomas Aidukas , Lars Loetgering , Andrew Robert Harvey

We consider an inverse problem of recovering a parameter appearing in all levels in a second-order hyperbolic equation from a single boundary measurement. The model is motivated from applications in photoacoustic tomography when one seeks…

Analysis of PDEs · Mathematics 2024-08-26 Shitao Liu , Gunther Uhlmann , Yang Yang

In a medium where the dielectric permittivity is perturbed in the presence of an acoustic wave, optical scattering generates frequency-shifted light. In this paper we consider the inverse problem of recovering the optical properties of this…

Analysis of PDEs · Mathematics 2019-10-14 Francis J. Chung , Jeremy G. Hoskins , John C. Schotland

Photo-Acoustic Tomography (PAT) can reconstruct a distribution of optical absorbers acting as instantaneous sound sources in subcutaneous microvasculature of a human breast. Adjoint methods for PAT, typically Time-Reversal (TR) and…

Numerical Analysis · Mathematics 2018-06-25 Hongxiang Lin , Takashi Azuma , Mehmet Burcin Unlu , Shu Takagi

Optical wavefront-shaping has emerged as a powerful tool to manipulate light in strongly scattering media. It enables diffraction-limited focusing and imaging at depths where conventional microscopy techniques fail. However, while most…

Optics · Physics 2014-03-04 T. Chaigne , O. Katz , A. C. Boccara , M. Fink , E. Bossy , S. Gigan

Photoacoustic tomography (PAT) offers high optical contrast with acoustic imaging depth, making it essential for biomedical applications. While many all-optical systems have been developed to address limitations of ultrasound transducers,…

Optics · Physics 2024-10-11 Taeil Yoon , Hakseok Ko , Jeongmyo Im , Euiheon Chung , Wonshik Choi , Byeong Ha Lee

Most reconstruction algorithms for photoacoustic imaging assume that the pressure field is measured by ultrasound sensors placed on a detection surface. However, such sensors do not measure pressure exactly due to their non-uniform…

Analysis of PDEs · Mathematics 2021-01-05 Sebastian Acosta

Fluorescent Optical Tomography (FOT) is a new bio-medical imaging method with wider industrial applications. It is currently intensely researched since it is very precise and with no side effects for humans, as it uses non-ionising red and…

Analysis of PDEs · Mathematics 2019-10-29 Nikos Katzourakis

Several centimeters below the skin lie multiple biomarkers, such as glucose, oxygenation, and blood flow. Monitoring these biomarkers regularly and in a non-invasive manner would enable early insight into metabolic status and vascular…

Medical Physics · Physics 2025-10-30 Talia Xu , Caitlin Smith , Charles Lo , Jami Shepherd , Gijs van Soest , Marco Zuniga

Fourier ptychography is a new computational microscopy technique that provides gigapixel-scale intensity and phase images with both wide field-of-view and high resolution. By capturing a stack of low-resolution images under different…

Photoacoustic imaging and sensing have been studied extensively to probe the optical absorption of biological tissue in multiple scales ranging from large organs to small molecules. However, its elastic oscillation characterization is…

Optics · Physics 2015-09-21 Fei Gao , Xiaohua Feng , Yuanjin Zheng

We propose a model-based image reconstruction method for photoacoustic tomography(PAT) involving a novel form of regularization and demonstrate its ability to recover good quality images from significantly reduced size datasets. The…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Nadaparambil Aravindakshan Rejesh , Sandeep Kumar Kalva , Manojit Pramanik , Muthuvel Arigovindan

In recent years, photoacoustics has attracted intensive research for both anatomical and functional biomedical imaging. However, the physical interaction between photoacoustic generated endogenous waves and an exogenous ultrasound wave is a…

Optics · Physics 2016-01-22 Fei Gao , Xiaohua Feng , Yuanjin Zheng , Claus-Dieter Ohl

The paper contains a simple approach to reconstruction in Thermoacoustic and Photoacoustic Tomography. The technique works for any geometry of point detectors placement and for variable sound speed satisfying a non-trapping condition. A…

Numerical Analysis · Mathematics 2009-11-13 Mark Agranovsky , Peter Kuchment

Ultrasound attenuation is caused by absorption and scattering in tissue and is thus a function of tissue composition, hence its imaging offers great potential for screening and differential diagnosis. In this paper we propose a novel method…

Signal Processing · Electrical Eng. & Systems 2019-10-15 Richard Rau , Ozan Unal , Dieter Schweizer , Valery Vishnevskiy , Orcun Goksel

In optical tomography a physical body is illuminated with near-infrared light and the resulting outward photon flux is measured at the object boundary. The goal is to reconstruct internal optical properties of the body, such as absorption…

Numerical Analysis · Mathematics 2016-01-20 Antti Hannukainen , Lauri Harhanen , Nuutti Hyvönen , Helle Majander

Quantum imaging is an advanced method for microscopy or investigating the optical properties of materials or bio-medical inspections with high accuracy, low noise, and extremely low photo-damage. In previous work, we proposed a quantum…

Optics · Physics 2025-05-09 Mousume Samad , Maki Shimizu , Yasuto Hijikata