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Efforts to automate the reconstruction of neural circuits from 3D electron microscopic (EM) brain images are critical for the field of connectomics. An important computation for reconstruction is the detection of neuronal boundaries. Images…

Computer Vision and Pattern Recognition · Computer Science 2015-08-21 Kisuk Lee , Aleksandar Zlateski , Ashwin Vishwanathan , H. Sebastian Seung

We show dense voxel embeddings learned via deep metric learning can be employed to produce a highly accurate segmentation of neurons from 3D electron microscopy images. A "metric graph" on a set of edges between voxels is constructed from…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Kisuk Lee , Ran Lu , Kyle Luther , H. Sebastian Seung

In the field of connectomics, neuroscientists seek to identify cortical connectivity comprehensively. Neuronal boundary detection from the Electron Microscopy (EM) images is often done to assist the automatic reconstruction of neuronal…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Wei Shen , Bin Wang , Yuan Jiang , Yan Wang , Alan Yuille

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi

Convolutional neural networks are state-of-the-art for various segmentation tasks. While for 2D images these networks are also computationally efficient, 3D convolutions have huge storage requirements and therefore, end-to-end training is…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Christoph Angermann , Markus Haltmeier

The most established method of reconstructing neural circuits from animals involves slicing tissue very thin, then taking mosaics of electron microscope (EM) images. To trace neurons across different images and through different sections,…

Quantitative Methods · Quantitative Biology 2013-04-23 Louis K. Scheffer , Bill Karsh , Shiv Vitaladevun

The science of solving clinical problems by analyzing images generated in clinical practice is known as medical image analysis. The aim is to extract information in an effective and efficient manner for improved clinical diagnosis. The…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Syed Muhammad Anwar , Muhammad Majid , Adnan Qayyum , Muhammad Awais , Majdi Alnowami , Muhammad Khurram Khan

To build the connectomics map of the brain, we developed a new algorithm that can automatically refine the Membrane Detection Probability Maps (MDPM) generated to perform automatic segmentation of electron microscopy (EM) images. To achieve…

Neural and Evolutionary Computing · Computer Science 2015-06-22 Xundong Wu

In recent years, deep convolutional neural networks (CNNs) have shown record-shattering performance in a variety of computer vision problems, such as visual object recognition, detection and segmentation. These methods have also been…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Jose Bernal , Kaisar Kushibar , Daniel S. Asfaw , Sergi Valverde , Arnau Oliver , Robert Martí , Xavier Lladó

In this article, we look into some essential aspects of convolutional neural networks (CNNs) with the focus on medical image segmentation. First, we discuss the CNN architecture, thereby highlighting the spatial origin of the data,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-18 Jeroen Bertels , David Robben , Robin Lemmens , Dirk Vandermeulen

Convolutional Neural Networks (CNNs) have been successful in solving tasks in computer vision including medical image segmentation due to their ability to automatically extract features from unstructured data. However, CNNs are sensitive to…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Minh Tran , Viet-Khoa Vo-Ho , Kyle Quinn , Hien Nguyen , Khoa Luu , Ngan Le

Convolutional Neural Networks have revolutionized vision applications. There are image domains and representations, however, that cannot be handled by standard CNNs (e.g., spherical images, superpixels). Such data are usually processed…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 David Hart , Michael Whitney , Bryan Morse

A novel method, utilizing convolutional neural networks (CNNs), is proposed to reconstruct hyperspectral cubes from computed tomography imaging spectrometer (CTIS) images. Current reconstruction algorithms are usually subject to long…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Wei-Chih Huang , Mads Svanborg Peters , Mads Juul Ahlebaek , Mads Toudal Frandsen , René Lynge Eriksen , Bjarke Jørgensen

The recent computer graphics developments have upraised the quality of the generated digital content, astonishing the most skeptical viewer. Games and movies have taken advantage of this fact but, at the same time, these advances have…

Computer Vision and Pattern Recognition · Computer Science 2017-11-29 Edmar R. S. de Rezende , Guilherme C. S. Ruppert , Antonio Theophilo , Tiago Carvalho

Convolutional Neural Networks (CNNs) are a class of artificial neural networks whose computational blocks use convolution, together with other linear and non-linear operations, to perform classification or regression. This paper explores…

Computer Vision and Pattern Recognition · Computer Science 2018-10-09 Victor Stamatescu , Mark D. McDonnell

Automated sample preparation and electron microscopy enables acquisition of very large image data sets. These technical advances are of special importance to the field of neuroanatomy, as 3D reconstructions of neuronal processes at the nm…

Convolutional neural networks (CNNs) were inspired by early findings in the study of biological vision. They have since become successful tools in computer vision and state-of-the-art models of both neural activity and behavior on visual…

Neurons and Cognition · Quantitative Biology 2020-02-11 Grace W. Lindsay

Computer-aided medical image analysis plays a significant role in assisting medical practitioners for expert clinical diagnosis and deciding the optimal treatment plan. At present, convolutional neural networks (CNN) are the preferred…

Image and Video Processing · Electrical Eng. & Systems 2022-04-29 S Niyas , S J Pawan , M Anand Kumar , Jeny Rajan

While initially devised for image categorization, convolutional neural networks (CNNs) are being increasingly used for the pixelwise semantic labeling of images. However, the proper nature of the most common CNN architectures makes them…

Computer Vision and Pattern Recognition · Computer Science 2017-04-24 Emmanuel Maggiori , Guillaume Charpiat , Yuliya Tarabalka , Pierre Alliez

Reconstructing multiple molecularly defined neurons from individual brains and across multiple brain regions can reveal organizational principles of the nervous system. However, high resolution imaging of the whole brain is a technically…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 James Gornet , Kannan Umadevi Venkataraju , Arun Narasimhan , Nicholas Turner , Kisuk Lee , H. Sebastian Seung , Pavel Osten , Uygar Sümbül
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