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Complex systems are often driven by higher-order interactions among multiple units, naturally represented as hypergraphs. Understanding dependency structures within these hypergraphs is crucial for understanding and predicting the behavior…

Social and Information Networks · Computer Science 2025-05-29 John Hood , Caterina De Bacco , Aaron Schein

Influence estimation aims to predict the total influence spread in social networks and has received surged attention in recent years. Most current studies focus on estimating the total number of influenced users in a social network, and…

Social and Information Networks · Computer Science 2023-08-22 Yingdan Shi , Jingya Zhou , Congcong Zhang

Diffusion probabilistic models have made their way into a number of high-profile applications since their inception. In particular, there has been a wave of research into using diffusion models in the prediction and design of biomolecular…

Biomolecules · Quantitative Biology 2024-06-05 Trevor Norton , Debswapna Bhattacharya

The behaviour of many real-world phenomena can be modelled by nonlinear dynamical systems whereby a latent system state is observed through a filter. We are interested in interacting subsystems of this form, which we model by a set of…

Machine Learning · Computer Science 2017-02-20 Oliver M. Cliff , Mikhail Prokopenko , Robert Fitch

Spatiotemporal patterns are common in biological systems. For electrically-coupled cells previous studies of pattern formation have mainly used external forcing as the main bifurcation parameter. The purpose of this paper is to show that…

Dynamical Systems · Mathematics 2021-11-02 H. O. Fatoyinbo , R. G. Brown , D. J. W. Simpson , B. van Brunt

Subdiffusion has been proposed as an explanation of various kinetic phenomena inside living cells. In order to fascilitate large-scale computational studies of subdiffusive chemical processes, we extend a recently suggested mesoscopic model…

Analysis of PDEs · Mathematics 2018-02-19 Emilie Blanc , Stefan Engblom , Andreas Hellander , Per Lötstedt

The understanding of neural activity patterns is fundamentally linked to an understanding of how the brain's network architecture shapes dynamical processes. Established approaches rely mostly on deviations of a given network from certain…

Neurons and Cognition · Quantitative Biology 2014-09-19 Marc-Thorsten Huett , Marcus Kaiser , Claus C. Hilgetag

Capturing intricate biological phenomena often requires multiscale modeling where coarse and inexpensive models are developed using limited components of expensive and high-fidelity models. Here, we consider such a multiscale framework in…

Quantitative Methods · Quantitative Biology 2022-07-12 Konstantia Georgouli , Helgi I Ingólfsson , Fikret Aydin , Mark Heimann , Felice C Lightstone , Peer-Timo Bremer , Harsh Bhatia

Retrieving cohesive subgraphs in networks is a fundamental problem in social network analysis and graph data management. These subgraphs can be used for marketing strategies or recommendation systems. Despite the introduction of numerous…

Social and Information Networks · Computer Science 2025-07-16 Dahee Kim , Song Kim , Jeongseon Kim , Junghoon Kim , Kaiyu Feng , Sungsu Lim , Jungeun Kim

Cell membranes phase separate into ordered ${\rm L_o}$ and disordered ${\rm L_d}$ domains depending on their compositions. This membrane compartmentalization is heterogeneous and regulates the localization of specific proteins related to…

Soft Condensed Matter · Physics 2023-08-11 Ken Sakamoto , Takuma Akimoto , Mayu Muramatsu , Mark S. P. Sansom , Ralf Metzler , Eiji Yamamoto

Time-resolved single-molecule biophysical experiments yield data that contain a wealth of dynamic information, in addition to the equilibrium distributions derived from histograms of the time series. In typical force spectroscopic setups…

Biomolecules · Quantitative Biology 2011-07-14 Michael Hinczewski , Yann von Hansen , Roland R. Netz

Our understanding of the dynamics of complex networked systems has increased significantly in the last two decades. However, most of our knowledge is built upon assuming pairwise relations among the system's components. This is often an…

Physics and Society · Physics 2020-04-15 Guilherme Ferraz de Arruda , Giovanni Petri , Yamir Moreno

The explosion of data throughout the biomedical sciences provides unprecedented opportunities to learn about the dynamics of evolution and disease progression, but harnessing these large and diverse datasets remains challenging. Here, we…

Quantitative Methods · Quantitative Biology 2019-12-03 Sam F. Greenbury , Mauricio Barahona , Iain G. Johnston

In recent years, there has been increasing interest in developing models and tools to address the complex patterns of connectivity found in brain tissue. Specifically, this is due to a need to understand how emergent properties emerge from…

Neurons and Cognition · Quantitative Biology 2022-04-15 Sean Knight , Navjot Gadda

Anatomical consistency in biomarker segmentation is crucial for many medical image analysis tasks. A promising paradigm for achieving anatomically consistent segmentation via deep networks is incorporating pixel connectivity, a basic…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Ziyun Yang , Sina Farsiu

A plethora of networks is being collected in a growing number of fields, including disease transmission, international relations, social interactions, and others. As data streams continue to grow, the complexity associated with these highly…

Machine Learning · Statistics 2018-09-11 Daniele Durante , Nabanita Mukherjee , Rebecca C. Steorts

The conformation space of a 20-residue antiparallel $\beta$-sheet peptide, sampled by molecular dynamics simulations, is mapped to a network. Conformations are nodes of the network, and the transitions between them are links. The…

Biomolecules · Quantitative Biology 2007-05-23 Francesco Rao , Amedeo Caflisch

Kernel-based non-linear dimensionality reduction methods, such as Local Linear Embedding (LLE) and Laplacian Eigenmaps, rely heavily upon pairwise distances or similarity scores, with which one can construct and study a weighted graph…

Statistics Theory · Mathematics 2019-08-06 Tingran Gao

This paper describes how realistic neuromorphic networks can have their connectivity properties fully characterized in analytical fashion. By assuming that all neurons have the same shape and are regularly distributed along the…

Disordered Systems and Neural Networks · Physics 2009-11-10 Luciano da F. Costa

Subdiffusion on graphs is often modeled by time-fractional diffusion equations, yet its structural and dynamical consequences remain unclear. We show that subdiffusive transport on graphs is a memory-driven process generated by a random…

Social and Information Networks · Computer Science 2026-01-22 Nikita Deniskin , Ernesto Estrada