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Agglomerative clustering has emerged as a vital tool in data analysis due to its intuitive and flexible characteristics. However, existing agglomerative clustering methods often involve additional parameters for sub-cluster partitioning and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Huan Yan , Junjie Hu

We address general-shaped clustering problems under very weak parametric assumptions with a two-step hybrid robust clustering algorithm based on trimmed k-means and hierarchical agglomeration. The algorithm has low computational complexity…

Methodology · Statistics 2022-01-19 Luca Insolia , Domenico Perrotta

The use of brain images as markers for diseases or behavioral differences is challenged by the small effects size and the ensuing lack of power, an issue that has incited researchers to rely more systematically on large cohorts. Coupled…

Machine Learning · Statistics 2015-11-17 Bertrand Thirion , Andrés Hoyos-Idrobo , Jonas Kahn , Gael Varoquaux

We present a novel coupled two-way clustering approach to gene microarray data analysis. The main idea is to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant…

Biological Physics · Physics 2009-11-06 G. Getz , E. Levine , E. Domany

In data stream clustering, systematic theory of stream clustering algorithms remains relatively scarce. Recently, density-based methods have gained attention. However, existing algorithms struggle to simultaneously handle arbitrarily…

Machine Learning · Computer Science 2026-05-07 Qifen Zeng , Haomin Bao , Yuanzhuo Hu , Zirui Zhang , Yuheng Zheng , Luosheng Wen

The rapid development of high-throughput sequencing technologies has led to an explosive increase in biological sequence data, making sequence clustering a fundamental task in large-scale bioinformatics analyses. Unlike traditional…

Genomics · Quantitative Biology 2026-01-22 Simeng Zhang , Xinying Liu , Jun Lou , Mudi Jiang , Quan Zou , Zengyou He

Recently, deep clustering, which is able to perform feature learning that favors clustering tasks via deep neural networks, has achieved remarkable performance in image clustering applications. However, the existing deep clustering…

Machine Learning · Computer Science 2018-12-12 Yazhou Ren , Ni Wang , Mingxia Li , Zenglin Xu

Hierarchical clustering remains a fundamental challenge in data mining, particularly when dealing with large-scale datasets where traditional approaches fail to scale effectively. Recent Chameleon-based algorithms - Chameleon2, M-Chameleon,…

Machine Learning · Computer Science 2025-10-07 Priyanshu Singh , Kapil Ahuja

Biologists often perform clustering analysis to derive meaningful patterns, relationships, and structures from data instances and attributes. Though clustering plays a pivotal role in biologists' data exploration, it takes non-trivial…

Human-Computer Interaction · Computer Science 2019-11-05 Bahador Saket , Subhajit Das , Bum Chul Kwon , Alex Endert

Network data appears in very diverse applications, like biological, social, or sensor networks. Clustering of network nodes into categories or communities has thus become a very common task in machine learning and data mining. Network data…

Machine Learning · Computer Science 2020-01-24 Mireille El Gheche , Giovanni Chierchia , Pascal Frossard

Clustering is often used for discovering structure in data. Clustering systems differ in the objective function used to evaluate clustering quality and the control strategy used to search the space of clusterings. Ideally, the search…

Artificial Intelligence · Computer Science 2014-11-17 D. Fisher

We formulate a novel technique for the detection of functional clusters in discrete event data. The advantage of this algorithm is that no prior knowledge of the number of functional groups is needed, as our procedure progressively combines…

Neurons and Cognition · Quantitative Biology 2015-05-13 S. Feldt , J. Waddell , V. L. Hetrick , J. D. Berke , M. Zochowski

Density-based clustering aims to find groups of similar objects (i.e., clusters) in a given dataset. Applications include, e.g., process mining and anomaly detection. It comes with two user parameters ({\epsilon}, MinPts) that determine the…

Background. Clustering analysis discovers hidden structures in a data set by partitioning them into disjoint clusters. Robust accuracy measures that evaluate the goodness of clustering results are critical for algorithm development and…

Machine Learning · Computer Science 2021-09-06 Navid Ahmadinejad , Li Liu

Clustering is a widely used unsupervised learning method for finding structure in the data. However, the resulting clusters are typically presented without any guarantees on their robustness; slightly changing the used data sample or…

Machine Learning · Statistics 2017-01-02 Andreas Henelius , Kai Puolamäki , Henrik Boström , Panagiotis Papapetrou

Mixed data comprises both numeric and categorical features, and mixed datasets occur frequently in many domains, such as health, finance, and marketing. Clustering is often applied to mixed datasets to find structures and to group similar…

Machine Learning · Computer Science 2019-03-20 Amir Ahmad , Shehroz S. Khan

We propose a deep clustering architecture alongside image segmentation for medical image analysis. The main idea is based on unsupervised learning to cluster images on severity of the disease in the subject's sample, and this image is then…

Image and Video Processing · Electrical Eng. & Systems 2020-05-28 Sharmin Pathan , Anant Tripathi

Biological functions are carried out by groups of interacting molecules, cells or tissues, known as communities. Membership in these communities may overlap when biological components are involved in multiple functions. However, traditional…

When measuring a range of different genomic, epigenomic, transcriptomic and other variables, an integrative approach to analysis can strengthen inference and give new insights. This is also the case when clustering patient samples, and…

Methodology · Statistics 2014-11-03 Kristoffer Hellton , Magne Thoresen

We propose a novel method for multiple clustering that assumes a co-clustering structure (partitions in both rows and columns of the data matrix) in each view. The new method is applicable to high-dimensional data. It is based on a…