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The paper considers the problem of performing a task defined on a model parameter that is only observed indirectly through noisy data in an ill-posed inverse problem. A key aspect is to formalize the steps of reconstruction and task as…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Jonas Adler , Sebastian Lunz , Olivier Verdier , Carola-Bibiane Schönlieb , Ozan Öktem

The Unfolded Protein Response is the cell mechanism for maintaining the balance of properly folded proteins in the endoplasmic reticulum , the specialized cellular compartment. Although it is largely studied from a biological point of view,…

Molecular Networks · Quantitative Biology 2023-04-05 Nicole Luchetti , Alessandro Loppini , Margherita Anna Grazia Matarrese , Letizia Chiodo , Simonetta Filippi

State estimation and sensor selection problems for nonlinear networks and systems are ubiquitous problems that are important for the control, monitoring, analysis, and prediction of a large number of engineered and physical systems. Sensor…

Systems and Control · Electrical Eng. & Systems 2021-03-23 Aleksandar Haber

Network-structured data becomes ubiquitous in daily life and is growing at a rapid pace. It presents great challenges to feature engineering due to the high non-linearity and sparsity of the data. The local and global structure of the…

Machine Learning · Computer Science 2025-01-31 Xin Sun , Zenghui Song , Yongbo Yu , Junyu Dong , Claudia Plant , Christian Boehm

Learning-based methods have demonstrated remarkable performance in solving inverse problems, particularly in image reconstruction tasks. Despite their success, these approaches often lack theoretical guarantees, which are crucial in…

Numerical Analysis · Mathematics 2025-10-21 Clemens Arndt , Judith Nickel

We introduce Neural Optimal Design of Experiments, a learning-based framework for optimal experimental design in inverse problems that avoids classical bilevel optimization and indirect sparsity regularization. NODE jointly trains a neural…

Machine Learning · Computer Science 2026-01-08 John E. Darges , Babak Maboudi Afkham , Matthias Chung

Deep learning-based models have demonstrated remarkable success in solving illposed inverse problems; however, many fail to strictly adhere to the physical constraints imposed by the measurement process. In this work, we introduce a…

Machine Learning · Computer Science 2025-05-22 Jorge Bacca

Structural controllability has been proposed as an analytical framework for making predictions regarding the control of complex networks across myriad disciplines in the physical and life sciences (Liu et al., Nature:473(7346):167-173,…

Physics and Society · Physics 2015-05-28 Noah J. Cowan , Erick J. Chastain , Daril A. Vilhena , James S. Freudenberg , Carl T. Bergstrom

Engineered infrastructure systems pose inverse problems in which hidden states, unknown parameters, and subsystem couplings must be inferred from sparse and noisy measurements. These problems are difficult because physical subsystems are…

Systems and Control · Electrical Eng. & Systems 2026-05-28 Esmaeil Ghorbani , Jürgen Hackl

Decision-making in complex systems often relies on machine learning models, yet highly accurate models such as XGBoost and neural networks can obscure the reasoning behind their predictions. In operations research applications,…

Machine Learning · Computer Science 2025-02-28 Gaurav Arwade , Sigurdur Olafsson

In the study of networked systems such as biological, technological, and social networks the available data are often uncertain. Rather than knowing the structure of a network exactly, we know the connections between nodes only with a…

Social and Information Networks · Computer Science 2016-01-20 Travis Martin , Brian Ball , M. E. J. Newman

Mechanical systems are often characterized only by their response to certain loads known from experiments or simulations. The obtained data can be used for various purposes: system analysis, design of mathematical models, or construction of…

Dynamical Systems · Mathematics 2026-01-05 Yevgeniya Filanova , Igor Pontes Duff , Pawan Goyal , Peter Benner

Motivated by the development and deployment of large-scale dynamical systems, often composed of geographically distributed smaller subsystems, we address the problem of verifying their controllability in a distributed manner. In this work…

Optimization and Control · Mathematics 2015-06-19 Joao Carvalho , Sergio Pequito , A. Pedro Aguiar , Soummya Kar , Karl H. Johansson

Networked systems are systems of interconnected components, in which the dynamics of each component are influenced by the behavior of neighboring components. Examples of networked systems include biological networks, critical…

Systems and Control · Computer Science 2016-06-01 Andrew Clark , Basel Alomair , Linda Bushnell , Radha Poovendran

It is widely believed that the success of deep convolutional networks is based on progressively discarding uninformative variability about the input with respect to the problem at hand. This is supported empirically by the difficulty of…

Machine Learning · Computer Science 2018-06-25 Jörn-Henrik Jacobsen , Arnold Smeulders , Edouard Oyallon

Accurate sensor placement is critical for modeling spatio-temporal systems such as environmental and climate processes. Neural Processes (NPs), particularly Convolutional Conditional Neural Processes (ConvCNPs), provide scalable…

Machine Learning · Computer Science 2025-12-01 Feyza Eksen , Stefan Oehmcke , Stefan Lüdtke

Sensor placement and feature selection are critical steps in engineering, modeling, and data science that share a common mathematical theme: the selected measurements should enable solution of an inverse problem. Most real-world systems of…

Optimization and Control · Mathematics 2022-08-24 Samuel E. Otto , Clarence W. Rowley

In a Networked Dynamical System (NDS), each node is a system whose dynamics are coupled with the dynamics of neighboring nodes. The global dynamics naturally builds on this network of couplings and it is often excited by a noise input with…

Machine Learning · Computer Science 2023-12-19 Augusto Santos , Diogo Rente , Rui Seabra , José M. F. Moura

Nonlinear causal discovery from observational data imposes strict identifiability assumptions on the formulation of structural equations utilized in the data generating process. The evaluation of structure learning methods under assumption…

Machine Learning · Statistics 2024-12-17 Georg Velev , Stefan Lessmann

The diffusion-driven Turing instability is a potential mechanism for spatial pattern formation in numerous biological and chemical systems. However, engineering these patterns and demonstrating that they are produced by this mechanism is…

Biological Physics · Physics 2025-12-02 Antonio Matas-Gil , Robert G. Endres