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In brain tumor resection, accurate removal of cancerous tissues while preserving eloquent regions is crucial to the safety and outcomes of the treatment. However, intra-operative tissue deformation (called brain shift) can move the surgical…

Image and Video Processing · Electrical Eng. & Systems 2023-07-28 Soorena Salari , Amirhossein Rasoulian , Hassan Rivaz , Yiming Xiao

Early surgical treatment of brain tumors is crucial in reducing patient mortality rates. However, brain tissue deformation (called brain shift) occurs during the surgery, rendering pre-operative images invalid. As a cost-effective and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Soorena Salari , Amirhossein Rasoulian , Hassan Rivaz , Yiming Xiao

Accurate intraoperative image guidance is critical for achieving maximal safe resection in brain tumor surgery, yet neuronavigation systems based on preoperative MRI lose accuracy during the procedure due to brain shift. Aligning…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Reuben Dorent , Laura Rigolo , Colin P. Galvin , Junyu Chen , Mattias P. Heinrich , Aaron Carass , Olivier Colliot , Demian Wassermann , Alexandra Golby , Tina Kapur , William Wells

During brain tumour resection, localising cancerous tissue and delineating healthy and pathological borders is challenging, even for experienced neurosurgeons and neuroradiologists. Intraoperative imaging is commonly employed for…

Intraoperative ultrasound (ioUS) is a valuable tool in brain tumor surgery due to its versatility, affordability, and seamless integration into the surgical workflow. However, its adoption remains limited, primarily because of the…

During neurosurgery, medical images of the brain are used to locate tumors and critical structures, but brain tissue shifts make pre-operative images unreliable for accurate removal of tumors. Intra-operative imaging can track these…

Registration of brain scans with pathologies is difficult, yet important research area. The importance of this task motivated researchers to organize the BraTS-Reg challenge, jointly with IEEE ISBI 2022 and MICCAI 2022 conferences. The…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Marek Wodzinski , Artur Jurgas , Niccolo Marini , Manfredo Atzori , Henning Muller

Current neurosurgical procedures utilize medical images of various modalities to enable the precise location of tumors and critical brain structures to plan accurate brain tumor resection. The difficulty of using preoperative images during…

During neurosurgical operations, surgeons can decide to acquire intraoperative data to better proceed with the removal of a tumor. A valid option is given by ultrasound (US) imaging, which can be easily obtained at subsequent surgical…

Image and Video Processing · Electrical Eng. & Systems 2020-01-13 Luca Canalini , Jan Klein , Dorothea Miller , Ron Kikinis

Registration of longitudinal brain MRI scans containing pathologies is challenging due to dramatic changes in tissue appearance. Although there has been progress in developing general-purpose medical image registration techniques, they have…

Intraoperative ultrasound (iUS) imaging has the potential to improve surgical outcomes in brain surgery. However, its interpretation is challenging, even for expert neurosurgeons. In this work, we designed the first patient-specific…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Reuben Dorent , Erickson Torio , Nazim Haouchine , Colin Galvin , Sarah Frisken , Alexandra Golby , Tina Kapur , William Wells

Registration of pre-operative and follow-up brain MRI scans is challenging due to the large variation of tissue appearance and missing correspondences in tumour recurrence regions caused by tumour mass effect. Although recent deep…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Tony C. W. Mok , Albert C. S. Chung

Purpose: Registration and segmentation of magnetic resonance (MR) and ultrasound (US) images play an essential role in surgical planning and resection of brain tumors. However, validating these techniques is challenging due to the scarcity…

Automatic segmentation of brain tumors in intra-operative ultrasound (iUS) images could facilitate localization of tumor tissue during resection surgery. The lack of large annotated datasets limits the current models performances. In this…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Mathilde Faanes , Ragnhild Holden Helland , Ole Solheim , Sébastien Muller , Ingerid Reinertsen

Deformable image registration is a key task in medical image analysis. The Brain Tumor Sequence Registration challenge (BraTS-Reg) aims at establishing correspondences between pre-operative and follow-up scans of the same patient diagnosed…

Image and Video Processing · Electrical Eng. & Systems 2022-12-12 Javid Abderezaei , Aymeric Pionteck , Agamdeep Chopra , Mehmet Kurt

Brain shift, i.e. the change in configuration of the brain after opening the dura mater, is a key problem in neuronavigation. We present an approach to co-register intra-operative microscope images with pre-operative MRI to adapt and…

Computer Vision and Pattern Recognition · Computer Science 2013-03-25 Benjamin Berkels , Ivan Cabrilo , Sven Haller , Martin Rumpf , Carlo Schaller

Intraoperative ultrasound imaging is used to facilitate safe brain tumour resection. However, due to challenges with image interpretation and the physical scanning, this tool has yet to achieve widespread adoption in neurosurgery. In this…

Intraoperative registration of real-time ultrasound (iUS) to preoperative Magnetic Resonance Imaging (MRI) remains an unsolved problem due to severe modality-specific differences in appearance, resolution, and field-of-view. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Daniil Morozov , Reuben Dorent , Nazim Haouchine

Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Xiaofeng Liu , Fangxu Xing , Chao Yang , C. -C. Jay Kuo , Georges ElFakhri , Jonghye Woo

Introduction: In neurosurgery, image-guided Neurosurgery Systems (IGNS) highly rely on preoperative brain magnetic resonance images (MRI) to assist surgeons in locating surgical targets and determining surgical paths. However, brain shift…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Jingjing Peng , Giorgio Fiore , Yang Liu , Ksenia Ellum , Debayan Daspupta , Keyoumars Ashkan , Andrew McEvoy , Anna Miserocchi , Sebastien Ourselin , John Duncan , Alejandro Granados
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