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Interstitial lung diseases are a large group of heterogeneous diseases characterized by different degrees of alveolitis and pulmonary fibrosis. Accurately diagnosing these diseases has significant guiding value for formulating treatment…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Huafeng Hu , Ruijie Ye , Jeyarajan Thiyagalingam , Frans Coenen , Jionglong Su

Causal discovery is becoming a key part in medical AI research. These methods can enhance healthcare by identifying causal links between biomarkers, demographics, treatments and outcomes. They can aid medical professionals in choosing more…

Herein we propose a deep learning-based approach for the prediction of lung lesion response based on radiomic features extracted from clinical CT scans of patients in non-small cell lung cancer trials. The approach starts with the…

Image and Video Processing · Electrical Eng. & Systems 2020-03-09 Antong Chen , Jennifer Saouaf , Bo Zhou , Randolph Crawford , Jianda Yuan , Junshui Ma , Richard Baumgartner , Shubing Wang , Gregory Goldmacher

Lung cancer is a very deadly disease worldwide, and its early diagnosis is crucial for increasing patient survival rates. Computed tomography (CT) scans are widely used for lung cancer diagnosis as they can give detailed lung structures.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Md Rashidul Islam , Bakary Gibba , Altagi Abdallah Bakheit Abdelgadir

Spiculations are important predictors of lung cancer malignancy, which are spikes on the surface of the pulmonary nodules. In this study, we proposed an interpretable and parameter-free technique to quantify the spiculation using area…

Computer Vision and Pattern Recognition · Computer Science 2020-10-16 Wookjin Choi , Saad Nadeem , Sadegh Riyahi , Joseph O. Deasy , Allen Tannenbaum , Wei Lu

Due to cellular heterogeneity, cell nuclei classification, segmentation, and detection from pathological images are challenging tasks. In the last few years, Deep Convolutional Neural Networks (DCNN) approaches have been shown…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

The LIDC-IDRI database is the most popular benchmark for lung cancer prediction. However, with subjective assessment from radiologists, nodules in LIDC may have entirely different malignancy annotations from the pathological ground truth,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-29 Hanxiao Zhang , Xiao Gu , Minghui Zhang , Weihao Yu , Liang Chen , Zhexin Wang , Feng Yao , Yun Gu , Guang-Zhong Yang

Robust localization of lymph nodes (LNs) in multiparametric MRI (mpMRI) is critical for the assessment of lymphadenopathy. Radiologists routinely measure the size of LN to distinguish benign from malignant nodes, which would require…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Tejas Sudharshan Mathai , Sungwon Lee , Thomas C. Shen , Zhiyong Lu , Ronald M. Summers

Lymph node (LN) metastasis status is one of the most critical prognostic and cancer staging factors for patients with resectable pancreatic ductal adenocarcinoma (PDAC), or in general, for any types of solid malignant tumors. Preoperative…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Zhilin Zheng , Xu Fang , Jiawen Yao , Mengmeng Zhu , Le Lu , Lingyun Huang , Jing Xiao , Yu Shi , Hong Lu , Jianping Lu , Ling Zhang , Chengwei Shao , Yun Bian

The accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies have introduced novel approaches for…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Yuan Jin , Gege Ma , Geng Chen , Tianling Lyu , Jan Egger , Junhui Lyu , Shaoting Zhang , Wentao Zhu

Lung cancer is the leading cause of cancer related mortality by a significant margin. While new technologies, such as image segmentation, have been paramount to improved detection and earlier diagnoses, there are still significant…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Marguerite B. Basta , Sarfaraz Hussein , Hsiang Hsu , Flavio P. Calmon

Nuclei classification provides valuable information for histopathology image analysis. However, the large variations in the appearance of different nuclei types cause difficulties in identifying nuclei. Most neural network based methods are…

Computer Vision and Pattern Recognition · Computer Science 2023-02-23 Wei Lou , Xiang Wan , Guanbin Li , Xiaoying Lou , Chenghang Li , Feng Gao , Haofeng Li

We propose a deep learning based method for classification of commonly occurring pathologies in chest X-ray images. The vast number of publicly available chest X-ray images provides the data necessary for successfully employing deep…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Mohammad S. Majdi , Khalil N. Salman , Michael F. Morris , Nirav C. Merchant , Jeffrey J. Rodriguez

The improved diagnostic accuracy of ultrasound breast examinations remains an important goal. In this study, we propose a biophysical feature based machine learning method for breast cancer detection to improve the performance beyond a…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Jihye Baek , Avice M. O'Connell , Kevin J. Parker

With the advanced imaging technology, digital pathology imaging of tumor tissue slides is becoming a routine clinical procedure for cancer diagnosis. This process produces massive imaging data that capture histological details in high…

Applications · Statistics 2020-12-10 Esteban Fernández Morales , Cong Zhang , Guanghua Xiao , Chul Moon , Qiwei Li

In this work, we address the challenge of binary lung nodule classification (benign vs malignant) using CT images by proposing a multi-level attention stacked ensemble of deep neural networks. Three pretrained backbones -- EfficientNet V2…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Uzzal Saha , Surya Prakash

The segmentation module which precisely outlines the nodules is a crucial step in a computer-aided diagnosis(CAD) system. The most challenging part of such a module is how to achieve high accuracy of the segmentation, especially for the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Xinliang Fu , Jiayin Zheng , Juanyun Mai , Yanbo Shao , Minghao Wang , Linyu Li , Zhaoqi Diao , Yulong Chen , Jianyu Xiao , Jian You , Airu Yin , Yang Yang , Xiangcheng Qiu , Jinsheng Tao , Bo Wang , Hua Ji

Background: AI-based classification models are essential for improving lung cancer diagnosis. However, the relative performance of lesion-level versus chest-region models in internal and external datasets remains unclear. Purpose: This…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Fakrul Islam Tushar

Accurately predicting and detecting interstitial lung disease (ILD) patterns given any computed tomography (CT) slice without any pre-processing prerequisites, such as manually delineated regions of interest (ROIs), is a clinically…

Computer Vision and Pattern Recognition · Computer Science 2017-01-23 Mingchen Gao , Ziyue Xu , Le Lu , Adam P. Harrison , Ronald M. Summers , Daniel J. Mollura
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