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The study of immune cellular composition has been of great scientific interest in immunology because of the generation of multiple large-scale data. From the statistical point of view, such immune cellular data should be treated as…

Applications · Statistics 2022-04-22 Jinkyung Yoo , Zequn Sun , Michael Greenacre , Qin Ma , Dongjun Chung , Young Min Kim

At the heart of causal structure learning from observational data lies a deceivingly simple question: given two statistically dependent random variables, which one has a causal effect on the other? This is impossible to answer using…

Machine Learning · Computer Science 2020-10-13 Nikolaos Nikolaou , Konstantinos Sechidis

A graph neural network transforms features in each vertex's neighborhood into a vector representation of the vertex. Afterward, each vertex's representation is used independently for predicting its label. This standard pipeline implicitly…

Machine Learning · Computer Science 2020-06-18 Junteng Jia , Austin R. Benson

Quantile regression is a powerful tool for detecting exposure-outcome associations given covariates across different parts of the outcome's distribution, but has two major limitations when the aim is to infer the effect of an exposure.…

Accurately estimating the proportion of true signals among a large number of variables is crucial for enhancing the precision and reliability of scientific research. Traditional signal proportion estimators often assume independence among…

Statistics Theory · Mathematics 2026-05-15 Jingtian Bai , Xinge Jessie Jeng

Representational similarity analysis (RSA) is a multivariate technique to investigate cortical representations of objects or constructs. While avoiding ill-posed matrix inversions that plague multivariate approaches in the presence of many…

Methodology · Statistics 2021-12-03 Roberto Viviani

Regression with compositional response or covariates, or even regression between parts of a composition, is frequently employed in social sciences. Among other possible applications, it may help to reveal interesting features in time…

Statistics Theory · Mathematics 2016-09-27 Ivo Muller , Karel Hron , Eva Fiserova , Jan Smahaj , Panajotis Cakirpaloglu , Jana Vancakova

Estimating causal effects from observational data is not always possible due to confounding. Identifying a set of appropriate covariates (adjustment set) and adjusting for their influence can remove confounding bias; however, such a set is…

Methodology · Statistics 2020-11-19 Sofia Triantafillou , Gregory Cooper

Scientific and business practices are increasingly resulting in large collections of randomized experiments. Analyzed together, these collections can tell us things that individual experiments in the collection cannot. We study how to learn…

Machine Learning · Statistics 2017-06-02 Alexander Peysakhovich , Dean Eckles

Existing effect measures for compositional features are inadequate for many modern applications, for example, in microbiome research, since they display traits such as high-dimensionality and sparsity that can be poorly modelled with…

Methodology · Statistics 2025-06-02 Anton Rask Lundborg , Niklas Pfister

Collapsibility deals with the conditions under which a conditional (on a covariate W) measure of association between two random variables X and Y equals the marginal measure of association, under the assumption of homogeneity over the…

Statistics Theory · Mathematics 2011-12-30 P. Vellaisamy

Causal knowledge is vital for effective reasoning in science, as causal relations, unlike correlations, allow one to reason about the outcomes of interventions. Algorithms that can discover causal relations from observational data are based…

Machine Learning · Statistics 2019-11-12 Anish Dhir , Ciarán M. Lee

We propose generalized additive partial linear models for complex data which allow one to capture nonlinear patterns of some covariates, in the presence of linear components. The proposed method improves estimation efficiency and increases…

Statistics Theory · Mathematics 2014-05-26 Li Wang , Lan Xue , Annie Qu , Hua Liang

When scholars study joint distributions of multiple variables, copulas are useful. However, if the variables are not linearly correlated with each other yet are still not independent, most of conventional copulas are not up to the task.…

Methodology · Statistics 2023-08-08 Kentaro Fukumoto

Many important quantities of interest are only partially identified from observable data: the data can limit them to a set of plausible values, but not uniquely determine them. This paper develops a unified framework for covariate-assisted…

Methodology · Statistics 2025-08-15 Eli Ben-Michael

We propose a partial information decomposition based on the newly introduced framework of causal tensors, i.e., multilinear stochastic maps that transform source data into destination data. This framework enables us to express an indirect…

Information Theory · Computer Science 2020-05-04 David Sigtermans

The past years have seen a drastic rise in studies devoted to the investigation of colexification patterns in individual languages families in particular and the languages of the world in specific. Specifically computational studies have…

Computation and Language · Computer Science 2023-02-03 Johann-Mattis List

Functional data analysis, which handles data arising from curves, surfaces, volumes, manifolds and beyond in a variety of scientific fields, is a rapidly developing area in modern statistics and data science in the recent decades. The…

Methodology · Statistics 2020-08-21 Xiaoke Zhang , Wu Xue , Qiyue Wang

Intelligent systems possess a crucial characteristic of breaking complicated problems into smaller reusable components or parts and adjusting to new tasks using these part representations. However, current part-learners encounter…

Machine Learning · Computer Science 2023-10-03 Gaurav Bhatt , Deepayan Das , Leonid Sigal , Vineeth N Balasubramanian

High-dimensional compositional data arise naturally in many applications such as metagenomic data analysis. The observed data lie in a high-dimensional simplex, and conventional statistical methods often fail to produce sensible results due…

Methodology · Statistics 2016-01-19 Yuanpei Cao , Wei Lin , Hongzhe Li