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The experimental design for a generalized linear model (GLM) is important but challenging since the design criterion often depends on model specification including the link function, the linear predictor, and the unknown regression…

Methodology · Statistics 2021-03-23 Yiou Li , Xinwei Deng

Technological advances have led to a proliferation of structured big data that have matrix-valued covariates. We are specifically motivated to build predictive models for multi-subject neuroimaging data based on each subject's brain imaging…

Methodology · Statistics 2015-05-15 Yue Hu , Genevera I. Allen

A class of nonlinear models combining a pharmacokinetic compartmental model and a pharmacodynamic Emax model is introduced. The locally D-optimal (LD) design for a four-parameter composed model is found to be a saturated four-point uniform…

Methodology · Statistics 2008-12-18 X. Fang , A. S. Hedayat

Subsampling is commonly used to overcome computational and economical bottlenecks in the analysis of finite populations and massive datasets. Existing methods are often limited in scope and use optimality criteria (e.g., A-optimality) with…

Statistics Theory · Mathematics 2023-04-07 Henrik Imberg , Marina Axelson-Fisk , Johan Jonasson

We develop adaptive discretization algorithms for locally optimal experimental design of nonlinear prediction models. With these algorithms, we refine and improve a pertinent state-of-the-art algorithm in various respects. We establish…

Optimization and Control · Mathematics 2024-06-04 Jochen Schmid , Philipp Seufert , Michael Bortz

The generalized linear models (GLMs) are widely used in statistical analysis and the related design issues are undoubtedly challenging. The state-of-the-art works mostly apply to design criteria on the estimates of regression coefficients.…

Methodology · Statistics 2020-04-21 Yiou Li , Xinwei Deng

The Poisson-Gamma model is a generalization of the Poisson model, which can be used for modelling count data. We show that the $D$-optimality criterion for the Poisson-Gamma model is equivalent to a combined weighted optimality criterion of…

Statistics Theory · Mathematics 2018-08-17 Marius Schmidt , Rainer Schwabe

The analytic characterization of the high-dimensional behavior of optimization for Generalized Linear Models (GLMs) with Gaussian data has been a central focus in statistics and probability in recent years. While convex cases, such as the…

Machine Learning · Statistics 2026-01-13 Matteo Vilucchio , Yatin Dandi , Matéo Pirio Rossignol , Cedric Gerbelot , Florent Krzakala

In this paper, we consider the multicollinearity problem in the gamma regression model when model parameters are linearly restricted. The linear restrictions are available from prior information to ensure the validity of scientific theories…

Methodology · Statistics 2023-03-10 Solmaz Seifollahi , Hossein Bevrani , Kaniav Kamary

For the last two decades, high-dimensional data and methods have proliferated throughout the literature. Yet, the classical technique of linear regression has not lost its usefulness in applications. In fact, many high-dimensional…

Statistics Theory · Mathematics 2021-05-18 Arun Kumar Kuchibhotla , Lawrence D. Brown , Andreas Buja , Edward I. George , Linda Zhao

Generative AI has redefined artificial intelligence, enabling the creation of innovative content and customized solutions that drive business practices into a new era of efficiency and creativity. In this paper, we focus on diffusion…

Machine Learning · Computer Science 2024-03-21 Zihao Li , Hui Yuan , Kaixuan Huang , Chengzhuo Ni , Yinyu Ye , Minshuo Chen , Mengdi Wang

In this paper we construct (locally) $D$-optimal designs for a wide class of non-linear multiple regression models, when the design region is a $k$-dimensional ball. For this construction we make use of the concept of invariance and…

Methodology · Statistics 2021-04-07 Martin Radloff , Rainer Schwabe

We present $\Gamma$-nets, a method for generalizing value function estimation over timescale. By using the timescale as one of the estimator's inputs we can estimate value for arbitrary timescales. As a result, the prediction target for any…

Machine Learning · Computer Science 2020-10-20 Craig Sherstan , Shibhansh Dohare , James MacGlashan , Johannes Günther , Patrick M. Pilarski

Analyzing ordinal data becomes increasingly important in psychology, especially in the context of item response theory. The generalized partial credit model (GPCM) is probably the most widely used ordinal model and finds application in many…

Statistics Theory · Mathematics 2018-10-22 Paul-Christian Bürkner , Rainer Schwabe , Heinz Holling

The ab initio extension of the dynamical vertex approximation (D$\Gamma$A) method allows for realistic materials calculations that include non-local correlations beyond $GW$ and dynamical mean-field theory. Here, we discuss the…

Strongly Correlated Electrons · Physics 2020-01-13 Anna Galler , Patrik Thunström , Josef Kaufmann , Matthias Pickem , Jan M. Tomczak , Karsten Held

The issue of determining not only an adequate dose but also a dosing frequency of a drug arises frequently in Phase II clinical trials. This results in the comparison of models which have some parameters in common. Planning such studies…

Methodology · Statistics 2017-11-16 Kirsten Schorning , Maria Konstantinou

In this paper, we discuss computational aspects to obtain accurate inferences for the parameters of the generalized gamma (GG) distribution. Usually, the solution of the maximum likelihood estimators (MLE) for the GG distribution have no…

Computation · Statistics 2017-07-26 Jorge Alberto Achcar , Pedro Luiz Ramos , Edson Zangiacomi Martinez

Implicit generative models have the capability to learn arbitrary complex data distributions. On the downside, training requires telling apart real data from artificially-generated ones using adversarial discriminators, leading to unstable…

Machine Learning · Computer Science 2024-02-27 José Manuel de Frutos , Pablo M. Olmos , Manuel A. Vázquez , Joaquín Míguez

This paper considers generalized linear models using rule-based features, also referred to as rule ensembles, for regression and probabilistic classification. Rules facilitate model interpretation while also capturing nonlinear dependences…

Machine Learning · Computer Science 2019-06-06 Dennis Wei , Sanjeeb Dash , Tian Gao , Oktay Günlük

Deep neural network learning can be formulated as a non-convex optimization problem. Existing optimization algorithms, e.g., Adam, can learn the models fast, but may get stuck in local optima easily. In this paper, we introduce a novel…

Machine Learning · Computer Science 2019-03-12 Jiawei Zhang , Fisher B. Gouza