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We propose a novel attention gate (AG) model for medical imaging that automatically learns to focus on target structures of varying shapes and sizes. Models trained with AGs implicitly learn to suppress irrelevant regions in an input image…

Reliable cell segmentation and classification from biomedical images is a crucial step for both scientific research and clinical practice. A major challenge for more robust segmentation and classification methods is the large variations in…

Cell Behavior · Quantitative Biology 2017-10-31 Mo Zhang , Xiang Li , Mengjia Xu , Quanzheng Li

The morphology of glands has been used routinely by pathologists to assess the malignancy degree of adenocarcinomas. Accurate segmentation of glands from histology images is a crucial step to obtain reliable morphological statistics for…

Computer Vision and Pattern Recognition · Computer Science 2016-04-12 Hao Chen , Xiaojuan Qi , Lequan Yu , Pheng-Ann Heng

Deep learning architecture with convolutional neural network (CNN) achieves outstanding success in the field of computer vision. Where U-Net, an encoder-decoder architecture structured by CNN, makes a great breakthrough in biomedical image…

Image and Video Processing · Electrical Eng. & Systems 2023-02-13 Qing Xu , Zhicheng Ma , Na HE , Wenting Duan

Medical image segmentation is crucial for the development of computer-aided diagnostic and therapeutic systems, but still faces numerous difficulties. In recent years, the commonly used encoder-decoder architecture based on CNNs has been…

Computer Vision and Pattern Recognition · Computer Science 2023-04-25 Davoud Saadati , Omid Nejati Manzari , Sattar Mirzakuchaki

Accurate detection and segmentation of glomeruli in kidney tissue are essential for diagnostic applications. Traditional deep learning methods primarily rely on semantic segmentation, which often fails to precisely delineate adjacent…

Tissues and Organs · Quantitative Biology 2026-04-17 Behnaz Elhaminia , Catherine King , Jiaqi Lv , Lorraine Harper , Paul Moss , Owen Cain , Dimitrios Chanouzas , Shan E Ahmed Raza

Deep convolutional neural network (CNN) achieves remarkable performance for medical image analysis. UNet is the primary source in the performance of 3D CNN architectures for medical imaging tasks, including brain tumor segmentation. The…

Image and Video Processing · Electrical Eng. & Systems 2020-11-30 Parvez Ahmad , Saqib Qamar , Linlin Shen , Adnan Saeed

Tubular structure segmentation in medical images, e.g., segmenting vessels in CT scans, serves as a vital step in the use of computers to aid in screening early stages of related diseases. But automatic tubular structure segmentation in CT…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yan Wang , Xu Wei , Fengze Liu , Jieneng Chen , Yuyin Zhou , Wei Shen , Elliot K. Fishman , Alan L. Yuille

Automatic segmentation of retinal vessels in fundus images plays an important role in the diagnosis of some diseases such as diabetes and hypertension. In this paper, we propose Deformable U-Net (DUNet), which exploits the retinal vessels'…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Qiangguo Jin , Zhaopeng Meng , Tuan D. Pham , Qi Chen , Leyi Wei , Ran Su

Recently, numerous pancreas segmentation methods have achieved promising performance on local single-source datasets. However, these methods don't adequately account for generalizability issues, and hence typically show limited performance…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Jun Li , Hongzhang Zhu , Tao Chen , Xiaohua Qian

Early detection improves prognosis in pancreatic ductal adenocarcinoma (PDAC) but is challenging as lesions are often small and poorly defined on contrast-enhanced computed tomography scans (CE-CT). Deep learning can facilitate PDAC…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Natália Alves , Megan Schuurmans , Geke Litjens , Joeran S. Bosma , John Hermans , Henkjan Huisman

Organ segmentation in CT volumes is an important pre-processing step in many computer assisted intervention and diagnosis methods. In recent years, convolutional neural networks have dominated the state of the art in this task. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Roger D. Soberanis-Mukul , Nassir Navab , Shadi Albarqouni

The high cure rate of cancer is inextricably linked to physicians' accuracy in diagnosis and treatment, therefore a model that can accomplish high-precision tumor segmentation has become a necessity in many applications of the medical…

Image and Video Processing · Electrical Eng. & Systems 2023-07-26 Zeqiu. Yu , Shuo. Han , Ziheng. Song

Pancreas segmentation in computed tomography imaging has been historically difficult for automated methods because of the large shape and size variations between patients. In this work, we describe a custom-build 3D fully convolutional…

Computer Vision and Pattern Recognition · Computer Science 2018-03-15 Holger Roth , Masahiro Oda , Natsuki Shimizu , Hirohisa Oda , Yuichiro Hayashi , Takayuki Kitasaka , Michitaka Fujiwara , Kazunari Misawa , Kensaku Mori

Precise segmentation of organs and tumors plays a crucial role in clinical applications. It is a challenging task due to the irregular shapes and various sizes of organs and tumors as well as the significant class imbalance between the…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Ziqiang Li , Hong Pan , Yaping Zhu , A. K. Qin

Deep learning has achieved tremendous success in computer vision, while medical image segmentation (MIS) remains a challenge, due to the scarcity of data annotations. Meta-learning techniques for few-shot segmentation (Meta-FSS) have been…

Computer Vision and Pattern Recognition · Computer Science 2023-03-08 Qianqian Shen , Yanan Li , Jiyong Jin , Bin Liu

Pancreatic cancer, which has a low survival rate, is one of the most challenging cancers to diagnose and treat effectively. Early detection through abdominal computed tomography (CT) scans is crucial, yet complicated by the pancreas'…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Xubei Zhang , Mikhail Y. Shalaginov , Tingying Helen Zeng

Abdominal organ segmentation from CT and MRI is an essential prerequisite for surgical planning and computer-aided navigation systems. It is challenging due to the high variability in the shape, size, and position of abdominal organs.…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Fabian Bongratz , Anne-Marie Rickmann , Christian Wachinger

The lethal nature of pancreatic ductal adenocarcinoma (PDAC) calls for early differential diagnosis of pancreatic cysts, which are identified in up to 16% of normal subjects, and some of which may develop into PDAC. Previous computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2018-06-20 Hongwei Li , Kanru Lin , Maximilian Reichert , Lina Xu , Rickmer Braren , Deliang Fu , Roland Schmid , Ji Li , Bjoern Menze , Kuangyu Shi

Pancreas segmentation is challenging due to the small proportion and highly changeable anatomical structure. It motivates us to propose a novel segmentation framework, namely Curriculum Knowledge Switching (CKS) framework, which decomposes…

Computer Vision and Pattern Recognition · Computer Science 2023-06-23 Yumou Tang , Kun Zhan , Zhibo Tian , Mingxuan Zhang , Saisai Wang , Xueming Wen