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Training deep neural networks for 3D segmentation tasks can be challenging, often requiring efficient and effective strategies to improve model performance. In this study, we introduce a novel approach, DeCode, that utilizes label-derived…

Cell detection in histopathology images is of great value in clinical practice. \textit{Convolutional neural networks} (CNNs) have been applied to cell detection to improve the detection accuracy, where cell annotations are required for…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Zipei Zhao , Fengqian Pang , Zhiwen Liu , Chuyang Ye

Over one in three people are affected by neurodegenerative disorders. Neural stem cells, which are multipotent regenerative cells with the potential to differentiate into any of the neural cell types, have immense therapeutic potential for…

Image and Video Processing · Electrical Eng. & Systems 2024-09-27 Nidhi Parthasarathy , Chandra Suda , Anika Mittal , Ian Young Chen , Ananya Jalihal

An automatic approach to counting any kind of cells could alleviate work of the experts and boost the research in fields such as regenerative medicine. In this paper, a method for microscopy cell counting using multiple frames (hence…

Computer Vision and Pattern Recognition · Computer Science 2018-02-01 Alexander Gomez Villa , Augusto Salazar , Igor Stefanini

An algorithm for digital signal analysis using convolutional neural networks (CNN) was developed in this work. The main objective of this algorithm is to make the analysis of experiments with active target time projection chambers more…

Signal Processing · Electrical Eng. & Systems 2022-03-11 G. F. Fortino , J. C. Zamora , L. E. Tamayose , N. S. T. Hirata , V. Guimaraes

Active Learning (AL) is increasingly important in a broad range of applications. Two main AL principles to obtain accurate classification with few labeled data are refinement of the current decision boundary and exploration of poorly…

Machine Learning · Computer Science 2012-10-19 Jens Roeder , Boaz Nadler , Kevin Kunzmann , Fred A. Hamprecht

Large scale analysis of source code, and in particular scientific source code, holds the promise of better understanding the data science process, identifying analytical best practices, and providing insights to the builders of scientific…

Machine Learning · Computer Science 2020-09-01 Ge Zhang , Mike A. Merrill , Yang Liu , Jeffrey Heer , Tim Althoff

Accurate cell counting is essential in various biomedical research and clinical applications, including cancer diagnosis, stem cell research, and immunology. Manual counting is labor-intensive and error-prone, motivating automation through…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Abdurahman Ali Mohammed , Catherine Fonder , Ying Wei , Wallapak Tavanapong , Donald S Sakaguchi , Qi Li , Surya K. Mallapragada

Background Analyzing images to accurately estimate the number of different cell types in the brain using automatic methods is a major objective in neuroscience. The automatic and selective detection and segmentation of neurons would be an…

Image and Video Processing · Electrical Eng. & Systems 2024-10-07 Antonio LaTorre , Lidia Alonso-Nanclares , José María Peña , Javier De Felipe

We present a new annotated microscopic cellular image dataset to improve the effectiveness of machine learning methods for cellular image analysis. Cell counting is an important step in cell analysis. Typically, domain experts manually…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Abdurahman Ali Mohammed , Catherine Fonder , Donald S. Sakaguchi , Wallapak Tavanapong , Surya K. Mallapragada , Azeez Idris

This paper focuses on camouflaged object detection (COD), which is a task to detect objects hidden in the background. Most of the current COD models aim to highlight the target object directly while outputting ambiguous camouflaged…

Computer Vision and Pattern Recognition · Computer Science 2021-11-01 Nobukatsu Kajiura , Hong Liu , Shin'ichi Satoh

Deep learning has proven to be more effective than other methods in medical image analysis, including the seemingly simple but challenging task of segmenting individual cells, an essential step for many biological studies. Comparative…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Valentina Vadori , Antonella Peruffo , Jean-Marie Graïc , Livio Finos , Livio Corain , Enrico Grisan

Segmentation of cell nuclei in microscopy images is a prevalent necessity in cell biology. Especially for three-dimensional datasets, manual segmentation is prohibitively time-consuming, motivating the need for automated methods.…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Peter Hirsch , Dagmar Kainmueller

Evolutionary computation methods have been successfully applied to neural networks since two decades ago, while those methods cannot scale well to the modern deep neural networks due to the complicated architectures and large quantities of…

Neural and Evolutionary Computing · Computer Science 2019-03-12 Yanan Sun , Bing Xue , Mengjie Zhang , Gary G. Yen

The capability of accurate prediction of protein functions and properties is essential in the biotechnology industry, e.g. drug development and artificial protein synthesis, etc. The main challenges of protein function prediction are the…

Quantitative Methods · Quantitative Biology 2021-12-02 Wei-Cheng Tseng , Po-Han Chi , Jia-Hua Wu , Min Sun

We propose a weakly-supervised cell tracking method that can train a convolutional neural network (CNN) by using only the annotation of "cell detection" (i.e., the coordinates of cell positions) without association information, in which…

Computer Vision and Pattern Recognition · Computer Science 2020-07-17 Hiroki Tokunaga , Brian Kenji Iwana , Yuki Teramoto , Akihiko Yoshizawa , Ryoma Bise

Unsupervised cell type identification is crucial for uncovering and characterizing heterogeneous populations in single cell omics studies. Although a range of clustering methods have been developed, most focus exclusively on intrinsic…

Artificial Intelligence · Computer Science 2025-12-12 Liang Peng , Haopeng Liu , Yixuan Ye , Cheng Liu , Wenjun Shen , Si Wu , Hau-San Wong

The need to count and localize repeating objects in an image arises in different scenarios, such as biological microscopy studies, production lines inspection, and surveillance recordings analysis. The use of supervised Convoutional Neural…

Computer Vision and Pattern Recognition · Computer Science 2021-11-17 Inbar Huberman-Spiegelglas , Raanan Fattal

We address the problem of computing the distribution of induced connected subgraphs, aka \emph{graphlets} or \emph{motifs}, in large graphs. The current state-of-the-art algorithms estimate the motif counts via uniform sampling, by…

Data Structures and Algorithms · Computer Science 2021-07-20 Marco Bressan , Stefano Leucci , Alessandro Panconesi

Street view images classification aiming at urban land use analysis is difficult because the class labels (e.g., commercial area), are concepts with higher abstract level compared to the ones of general visual tasks (e.g., persons and…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Kun Zhao , Yongkun Liu , Siyuan Hao , Shaoxing Lu , Hongbin Liu , Lijian Zhou
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