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Due to the complexity of cancer, clustering algorithms have been used to disentangle the observed heterogeneity and identify cancer subtypes that can be treated specifically. While kernel based clustering approaches allow the use of more…

Machine Learning · Statistics 2018-11-21 Nora K. Speicher , Nico Pfeifer

In data containing heterogeneous subpopulations, classification performance benefits from incorporating the knowledge of cluster structure in the classifier. Previous methods for such combined clustering and classification either 1) are…

Machine Learning · Computer Science 2023-01-04 Shivin Srivastava , Siddharth Bhatia , Lingxiao Huang , Lim Jun Heng , Kenji Kawaguchi , Vaibhav Rajan

Cancer is a number of related yet highly heterogeneous diseases. Correct identification of cancer subtypes is critical for clinical decisions. The advance in sequencing technologies has made it possible to study cancer based on abundant…

Applications · Statistics 2018-11-27 Xiaochun Chen , Honggang Wang , Donghui Yan

Clustering is a standard approach for achieving efficient and scalable performance in wireless sensor networks. Traditionally, clustering algorithms aim at generating a number of disjoint clusters that satisfy some criteria. In this paper,…

Networking and Internet Architecture · Computer Science 2013-04-09 Moustafa Youssef , Adel Youssef , Mohamed Younis

We propose the Compact Clustering Attention (COCA) layer, an effective building block that introduces a hierarchical strategy for object-centric representation learning, while solving the unsupervised object discovery task on single images.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Can Küçüksözen , Yücel Yemez

In this chapter we review the main literature related to kernel spectral clustering (KSC), an approach to clustering cast within a kernel-based optimization setting. KSC represents a least-squares support vector machine based formulation of…

Machine Learning · Computer Science 2015-05-05 Rocco Langone , Raghvendra Mall , Carlos Alzate , Johan A. K. Suykens

Motivation: The size of available omics datasets is steadily increasing with technological advancement in recent years. While this increase in sample size can be used to improve the performance of relevant prediction tasks in healthcare,…

Quantitative Methods · Quantitative Biology 2023-05-04 Jonas C. Ditz , Bernhard Reuter , Nico Pfeifer

Quantum Machine Learning (QML) is a red-hot field that brings novel discoveries and exciting opportunities to resolve, speed up, or refine the analysis of a wide range of computational problems. In the realm of biomedical research and…

Machine Learning · Computer Science 2024-10-04 Mandeep Kaur Saggi , Amandeep Singh Bhatia , Mensah Isaiah , Humaira Gowher , Sabre Kais

Rapid technological advances have allowed for molecular profiling across multiple omics domains from a single sample for clinical decision making in many diseases, especially cancer. As tumor development and progression are dynamic…

Methodology · Statistics 2022-02-11 Dongyan Yan , Subharup Guha

Multiple datasets containing different types of features may be available for a given task. For instance, users' profiles can be used to group users for recommendation systems. In addition, a model can also use users' historical behaviors…

Machine Learning · Computer Science 2016-05-10 Weixiang Shao , Xiaoxiao Shi , Philip S. Yu

Integration of heterogeneous and high-dimensional multi-omics data is becoming increasingly important in understanding genetic data. Each omics technique only provides a limited view of the underlying biological process and integrating…

Machine Learning · Computer Science 2023-04-13 Chen Zhao , Anqi Liu , Xiao Zhang , Xuewei Cao , Zhengming Ding , Qiuying Sha , Hui Shen , Hong-Wen Deng , Weihua Zhou

Multiple instance learning (MIL) has shown significant promise in histopathology whole slide image (WSI) analysis for cancer diagnosis and prognosis. However, the inherent spatial heterogeneity of WSIs presents critical challenges, as…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Junjian Li , Jin Liu , Hulin Kuang , Hailin Yue , Mengshen He , Jianxin Wang

In cancer research, clustering techniques are widely used for exploratory analyses and dimensionality reduction, playing a critical role in the identification of novel cancer subtypes, often with direct implications for patient management.…

The analysis of cancer omics data is a "classic" problem, however, still remains challenging. Advancing from early studies that are mostly focused on a single type of cancer, some recent studies have analyzed data on multiple "related"…

Methodology · Statistics 2022-12-01 Yifan Sun , Yu Jiang , Yang Li , Shuangge Ma

In this thesis, we propose several modelling strategies to tackle evolving data in different contexts. In the framework of static clustering, we start by introducing a soft kernel spectral clustering (SKSC) algorithm, which can better deal…

Social and Information Networks · Computer Science 2014-11-24 Rocco Langone

\texttt{rCOSA} is a software package interfaced to the R language. It implements statistical techniques for clustering objects on subsets of attributes in multivariate data. The main output of COSA is a dissimilarity matrix that one can…

Computation · Statistics 2016-12-02 Maarten M. Kampert , Jacqueline J. Meulman , Jerome H. Friedman

While convolution and self-attention are extensively used in learned image compression (LIC) for transform coding, this paper proposes an alternative called Contextual Clustering based LIC (CLIC) which primarily relies on clustering…

Image and Video Processing · Electrical Eng. & Systems 2024-01-23 Yichi Zhang , Zhihao Duan , Ming Lu , Dandan Ding , Fengqing Zhu , Zhan Ma

Many similarity-based clustering methods work in two separate steps including similarity matrix computation and subsequent spectral clustering. However, similarity measurement is challenging because it is usually impacted by many factors,…

Machine Learning · Computer Science 2017-05-04 Zhao Kang , Chong Peng , Qiang Cheng

The advancements in data acquisition, storage, and processing techniques have resulted in the rapid growth of heterogeneous medical data. Integrating radiological scans, histopathology images, and molecular information with clinical data is…

Machine Learning · Computer Science 2023-12-25 Aakash Tripathi , Asim Waqas , Kavya Venkatesan , Yasin Yilmaz , Ghulam Rasool

The task of clustering a set of objects based on multiple sources of data arises in several modern applications. We propose an integrative statistical model that permits a separate clustering of the objects for each data source. These…

Machine Learning · Statistics 2015-12-01 Eric F. Lock , David B. Dunson
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