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We present an approach to learning regular spatial transformations between image pairs in the context of medical image registration. Contrary to optimization-based registration techniques and many modern learning-based methods, we do not…

Regularization is a popular technique to solve the overfitting problem of machine learning algorithms. Most regularization technique relies on parameter selection of the regularization coefficient. Plug-in method and cross-validation…

Machine Learning · Computer Science 2022-05-24 Hao Wang

The transcriptomics of cancer tumors are characterized with tens of thousands of gene expression features. Patient prognosis or tumor stage can be assessed by machine learning techniques like supervised classification tasks given a gene…

Machine Learning · Computer Science 2020-04-13 Martin Palazzo , Patricio Yankilevich , Pierre Beauseroy

An automated segmentation and classification of nuclei is an essential task in digital pathology. The current deep learning-based approaches require a vast amount of annotated datasets by pathologists. However, the existing datasets are…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Tan Nhu Nhat Doan , Kyungeun Kim , Boram Song , Jin Tae Kwak

Error accumulation is an essential component of the Top-$k$ sparsification method in distributed gradient descent. It implicitly scales the learning rate and prevents the slow-down of lateral movement, but it can also deteriorate…

Machine Learning · Computer Science 2024-09-24 Ali Bereyhi , Ben Liang , Gary Boudreau , Ali Afana

Regularization is a fundamental technique to prevent over-fitting and to improve generalization performances by constraining a model's complexity. Current Deep Networks heavily rely on regularizers such as Data-Augmentation (DA) or…

Machine Learning · Computer Science 2022-04-12 Randall Balestriero , Leon Bottou , Yann LeCun

Saliency maps have become a widely used method to make deep learning models more interpretable by providing post-hoc explanations of classifiers through identification of the most pertinent areas of the input medical image. They are…

The scarcity of pixel-level annotation is a prevalent problem in medical image segmentation tasks. In this paper, we introduce a novel regularization strategy involving interpolation-based mixing for semi-supervised medical image…

Image and Video Processing · Electrical Eng. & Systems 2022-02-04 Hritam Basak , Rajarshi Bhattacharya , Rukhshanda Hussain , Agniv Chatterjee

We explore several oversampling techniques for an imbalanced multi-label classification problem, a setting often encountered when developing models for Computer-Aided Diagnosis (CADx) systems. While most CADx systems aim to optimize…

Machine Learning · Computer Science 2018-07-10 Matthew Yung , Eli T. Brown , Alexander Rasin , Jacob D. Furst , Daniela S. Raicu

Over-parameterized deep neural networks trained by simple first-order methods are known to be able to fit any labeling of data. Such over-fitting ability hinders generalization when mislabeled training examples are present. On the other…

Machine Learning · Computer Science 2020-10-06 Wei Hu , Zhiyuan Li , Dingli Yu

How to extract more and useful information for single image super resolution is an imperative and difficult problem. Learning-based method is a representative method for such task. However, the results are not so stable as there may exist…

Image and Video Processing · Electrical Eng. & Systems 2020-03-25 Hu Liang , Shengrong Zhao

Error accumulation is effective for gradient sparsification in distributed settings: initially-unselected gradient entries are eventually selected as their accumulated error exceeds a certain level. The accumulation essentially behaves as a…

Machine Learning · Computer Science 2026-02-17 Ali Bereyhi , Ben Liang , Gary Boudreau , Ali Afana

Generalization is a central problem in Machine Learning. Indeed most prediction methods require careful calibration of hyperparameters usually carried out on a hold-out \textit{validation} dataset to achieve generalization. The main goal of…

Machine Learning · Statistics 2021-02-18 Karim Lounici , Katia Meziani , Benjamin Riu

Several works have aimed to explain why overparameterized neural networks generalize well when trained by Stochastic Gradient Descent (SGD). The consensus explanation that has emerged credits the randomized nature of SGD for the bias of the…

Machine Learning · Computer Science 2021-02-24 Shengchao Liu , Dimitris Papailiopoulos , Dimitris Achlioptas

Multi-task learning can suffer from destructive task interference, where jointly trained models underperform single-task baselines and limit generalization. To improve generalization performance in breast ultrasound-based tumor segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Jingru Zhang , Saed Moradi , Ashirbani Saha

Adversarially robust models are locally smooth around each data sample so that small perturbations cannot drastically change model outputs. In modern systems, such smoothness is usually obtained via Adversarial Training, which explicitly…

Machine Learning · Computer Science 2024-10-01 Adrián Rodríguez-Muñoz , Tongzhou Wang , Antonio Torralba

In high-stakes applications of machine learning models, interpretability methods provide guarantees that models are right for the right reasons. In medical imaging, saliency maps have become the standard tool for determining whether a…

Computer Vision and Pattern Recognition · Computer Science 2019-12-05 Jacob Pfau , Albert T. Young , Maria L. Wei , Michael J. Keiser

Regularizing the gradient norm of the output of a neural network with respect to its inputs is a powerful technique, rediscovered several times. This paper presents evidence that gradient regularization can consistently improve…

Machine Learning · Computer Science 2018-05-28 Dániel Varga , Adrián Csiszárik , Zsolt Zombori

Recent advancements in domain generalization for deepfake detection have attracted significant attention, with previous methods often incorporating additional modules to prevent overfitting to domain-specific patterns. However, such…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Lingyu Qiu , Ke Jiang , Xiaoyang Tan

Generalization is an important attribute of machine learning models, particularly for those that are to be deployed in a medical context, where unreliable predictions can have real world consequences. While the failure of models to…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Brennan Nichyporuk , Jillian Cardinell , Justin Szeto , Raghav Mehta , Jean-Pierre R. Falet , Douglas L. Arnold , Sotirios A. Tsaftaris , Tal Arbel