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We introduce the Stackelberg kidney exchange problem. In this problem, an agent (e.g. a hospital or a national organization) has control over a number of incompatible patient-donor pairs whose patients are in need of a transplant. The agent…

Computer Science and Game Theory · Computer Science 2020-07-08 Bart Smeulders , Danny Blom , Frits C. R. Spieksma

We design a flexible algorithm that exploits deceased donor kidneys to initiate chains of living donor kidney paired donations, combining deceased and living donor allocation mechanisms to improve the quantity and quality of kidney…

Tissues and Organs · Quantitative Biology 2019-01-09 Cristina Cornelio , Lucrezia Furian , Antonio Nicolo' , Francesca Rossi

Balancing fairness and efficiency in resource allocation is a classical economic and computational problem. The price of fairness measures the worst-case loss of economic efficiency when using an inefficient but fair allocation rule; for…

Computer Science and Game Theory · Computer Science 2017-09-11 Duncan C. McElfresh , John P. Dickerson

Incompatibility between patient and donor is a major barrier in kidney transplantation (KT). The increasing shortage of kidney donors has driven the development of desensitization techniques to overcome this immunological challenge.…

Systems and Control · Electrical Eng. & Systems 2025-04-29 Xingyu Ren , Michael C. Fu , Steven I. Marcus

Motivated by the real-world problem of international kidney exchange (IKEP), recent literature introduced a generalized transferable utility matching game featuring a partition of the vertex set of a graph into players, and analyzed its…

Computer Science and Game Theory · Computer Science 2026-02-24 Gergely Csáji , Tamás Király , Zsuzsa Mészáros-Karkus

Kidney Exchange Programs (KEPs) promote access to living donor trans- plantation for patients suffering from end stage renal disease. The HLA compatibility between transplant recipients and donors plays an important role when solving the…

Optimization and Control · Mathematics 2025-10-17 Valentina Peralta Clarke , Hans de Ferrante , Francisco Perez Galarce , Joris van de Klundert

Kidney transplantation is the preferred treatment for end-stage renal disease, yet the scarcity of donors and inefficiencies in allocation systems create major bottlenecks, resulting in prolonged wait times and alarming mortality rates.…

Computer Science and Game Theory · Computer Science 2024-10-15 Sean Berry , Berk Gorgulu , Sait Tunc , Mucahit Cevik , Matthew J Ellis

Motivated by kidney exchange, we study the following mechanism-design problem: On a directed graph (of transplant compatibilities among patient-donor pairs), the mechanism must select a simple path (a chain of transplantations) starting at…

Computer Science and Game Theory · Computer Science 2021-06-23 Avrim Blum , Paul Gölz

We study an elementary path problem which appears in the pricing step of a column generation scheme solving the kidney exchange problem. The latter aims at finding exchanges of donations in a pool of patients and donors of kidney…

Data Structures and Algorithms · Computer Science 2022-01-24 Lucie Pansart , Hadrien Cambazard , Nicolas Catusse

Relatives and friends of an end-stage renal disease patient who offer to donate a kidney are often found to be incompatible with their intended recipients. Kidney paired donation matches one patient and his incompatible donor with another…

Computer Science and Game Theory · Computer Science 2017-10-24 Sommer Gentry , Michal Mankowski , T. S. Michael , Dorry Segev

The optimal moment to start renal replacement therapy in a patient with acute kidney injury (AKI) remains a challenging problem in intensive care nephrology. Multiple randomised controlled trials have tried to answer this question, but…

Applications · Statistics 2022-06-10 Pawel Morzywolek , Johan Steen , Wim Van Biesen , Johan Decruyenaere , Stijn Vansteelandt

We introduce partitioned matching games as a suitable model for international kidney exchange programmes, where in each round the total number of available kidney transplants needs to be distributed amongst the participating countries in a…

Computer Science and Game Theory · Computer Science 2024-01-23 Márton Benedek , Péter Biró , Walter Kern , Dömötör Pálvölgyi , Daniël Paulusma

This paper addresses the problem of maximizing the expected size of a matching in the case of unreliable vertices and/or edges. The assumption is that upon failure, remaining vertices that have not been matched may be subject to a new…

Data Structures and Algorithms · Computer Science 2016-05-30 João Pedro Pedroso , Shiro Ikeda

Over 10,000 candidates wait for a kidney transplantation in Eurotransplant, and are prioritized for transplantation based on the allocation rules of the Eurotransplant Kidney Allocation System (ETKAS) and Eurotransplant Senior Program…

Computers and Society · Computer Science 2025-02-24 H. C. de Ferrante , Rocio Laguna Goya , Bart M. L. Smeulders , Frits C. R. Spieksma , Ineke Tieken

In the query-commit problem we are given a graph where edges have distinct probabilities of existing. It is possible to query the edges of the graph, and if the queried edge exists then its endpoints are irrevocably matched. The goal is to…

Data Structures and Algorithms · Computer Science 2011-10-06 Marco Molinaro , R. Ravi

The seminal work of Roth, S\"onmez, & \"Unver shows that the Edmonds-Gallai structure theorem for non-bipartite matching can be leveraged to yield a randomized algorithm to match patient-donor pairs in kidney exchange with extraordinarily…

Data Structures and Algorithms · Computer Science 2026-05-20 Claire Chang , Arin Khare , David Shmoys

Despite efforts to increase the supply of organs from living donors, most kidney transplants performed in Australia still come from deceased donors. The age of these donated organs has increased substantially in recent decades as the rate…

Computer Science and Game Theory · Computer Science 2017-10-19 Toby Walsh

A kidney transplant can improve the life expectancy and quality of life of patients with end-stage renal failure. Even more patients could be helped with a transplant if the rate of kidneys that are discarded and not transplanted could be…

This paper introduces a new learning-based approach for approximately solving the Kidney-Exchange Problem (KEP), an NP-hard problem on graphs. The problem consists of, given a pool of kidney donors and patients waiting for kidney donations,…

Machine Learning · Computer Science 2023-04-21 Pedro Foletto Pimenta , Pedro H. C. Avelar , Luis C. Lamb

While kidney transplants are seen as the best treatment option for patients with end-stage renal disease and kidney failure, the organ's health depends on the dosage of immunosuppressant drugs post-transplantation. Due to the dosage…

Quantitative Methods · Quantitative Biology 2023-09-19 Kapil Panda , Anirudh Mazumder