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Hadron therapy, because of the dosimetric and radiobiological advantages, is more and more often used in tumour treatment. This treatment method leads also to the radioactive effects induced by energetic protons on nuclei. Nuclear reactions…

Medical Physics · Physics 2018-04-26 Przemysław Sękowski , Izabela Skwira-Chalot , Tomasz Matulewicz

Background : Proton flash therapy is an emergency research topic in radiation therapy since the Varian announced the promising results from the first in human clinical trial of Flash therapy recently. However, it still needs a lot of…

The personal (or active) electronic dosimeters (PEDs) are devices used to determine the individual exposure to ionizing radiations and they are employed in hospitals, research laboratories and nuclear power plants. The PDOZ project is a…

Introduction: We developed and evaluated a method for dose calibration and monitoring under conventional and ultra-high dose rates for small animal experiments with small-field proton beams using a Faraday cup. Methods: We determined a…

Radiation dose is an important performance indicator of a dedicated breast CT (DBCT). In this paper, the method of putting thermoluminescent dosimeters (TLD) into a breast shaped PMMA phantom to study the dose distribution in breasts was…

Medical Physics · Physics 2013-05-14 Shen Shan-Wei , Wang Yan-Fang , Shu Hang , Tang Xiao , Wei Cun-Feng , Song Yu-Shou , Shi Rong-Jian , Wei Long

Laser-driven plasma wakefields can provide hundreds of MeV electron beam in mm-range distances potentially shrinking the dimension of the actual particle accelerators. The plasma density plays a fundamental role in the control and stability…

Technological tests of Total Ionizing Dose effects are required not only for silicon particle sensors developed in high energy physics experiments, but also for electronic devices and semiconductor elements used in commercial, automotive…

Instrumentation and Detectors · Physics 2022-06-13 Benedetto Di Ruzza

The widespread diffusion of precision radiotherapy techniques, geared toward the release of larger dose gradients in shorter time frames, is leading to new challenges in dosimetry. Accurate dose measurements are essential to check for beam…

Medical Physics · Physics 2022-05-17 S. Pettinato , M. Girolami , R. Olivieri , A. Stravato , C. Caruso , S. Salvatori

Currently, radiobiology experiments using heavy ions at GANIL(Grand Accelerateur National d Ions Lourds) are conducted under the supervision of the CIMAP (Center for research on Ions, MAterials and Photonics). In this context, a new beam…

Laser-driven proton sources have long been developed with an eye on their potential for medical application to radiation therapy. These sources are compact, versatile, and show peculiar characteristics such as extreme instantaneous dose…

DC-SRF-II gun, a high-brightness continuous-wave photocathode gun, has greater potential in electron beam irradiation applications. This paper presents the in-vacuum and in-air irradiation dosimetry study of the high repetition rate…

Accelerator Physics · Physics 2024-11-26 Jianhan Sun , Jianfeng Lv , Shang Tian , Juntao Liu , Zihao Zhang , Hang Xu , Lin Lin , Senlin Huang

Our purpose is to measure the internal radiation dose (ID) using human blood sample. In the literature, there is no process that allows the direct measurement of ID received by a person. This study has shown that it is possible to determine…

Thermoluminescence (TL) characteristics for LiF:Mg,Cu,P, and CaSO$_4$:Dy under the homogeneous field of X-ray beams of diagnostic irradiation and its verification using thermoluminescence dosimetry is presented. The irradiation were…

Micro-scale implantable medical devices (IMDs) extend the immense benefits of sensors used in health management. However, their development is limited by many requirements and challenges, such as the use of safe materials, size…

Information Theory · Computer Science 2018-06-19 Michael Okwori , Ali Behfarnia , Phanikumar Vuka , Ali Eslami

Droplet microlasers, as promising tools for biophotonics and biomedical sciences, have witnessed rapid advances due to their flexible reconfigurability, high sensitivity to stimuli, and label-free biosensing ability. However, designing…

Currently, gold nanorods can be synthesized in a wide range of sizes. However, for intended biological applications gold nanorods with approximate dimensions 50 nm x 15 nm are used. We investigate by computer simulation the effect of…

Medical Physics · Physics 2015-06-15 Constantin Ungureanu , Gerben A. Koning , Ton G. van Leeuwen , Srirang Manohar

Minibeam and microbeam radiation therapy promise improved treatment outcomes through reduced normal tissue toxicity at better tumor control rates. The lack of suitable compact radiation sources limits the clinical application of minibeams…

We present the design and preliminary calibration results of a novel highly miniaturised particle radiation monitor (HMRM) for spacecraft use. The HMRM device comprises a telescopic configuration of active pixel sensors enclosed in a…

In this paper, we present a robotic device for mouse tail vein injection. We propose a mouse holding mechanism to realize vein injection without anesthetizing the mouse, which consists of a tourniquet, vacuum port, and adaptive tail-end…

Ultra-high dose rate electron sources require dose rate independent dosimeters and a calibrated dose control system for accurate delivery. In this study, we developed a single-pulse dose monitoring and a real-time dose-based control system…