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Examining task-free functional connectivity (FC) in the human brain offers insights on how spontaneous integration and segregation of information relate to human cognition, and how this organization may be altered in different conditions,…

Human braingraphs or connectomes are widely studied in the last decade to understand the structural and functional properties of our brain. In the last several years our research group has computed and deposited thousands of human…

Neurons and Cognition · Quantitative Biology 2024-12-03 Balint Varga , Vince Grolmusz

With recent advancements in non-invasive techniques for measuring brain activity, such as magnetic resonance imaging (MRI), the study of structural and functional brain networks through graph signal processing (GSP) has gained notable…

Machine Learning · Computer Science 2025-11-13 Martín Schmidt , Sara Silva , Federico Larroca , Gonzalo Mateos , Pablo Musé

How intelligence emerges from living beings has been a fundamental question in neuroscience. However, it remains largely unanswered due to the complex neuronal dynamics and intricate connections between neurons in real neural systems. To…

Neurons and Cognition · Quantitative Biology 2024-09-04 Xiaoyu Zhang , Pengcheng Yang , Jiawei Feng , Qiang Luo , Wei Lin , Xin Lu

Advanced brain imaging techniques make it possible to measure individuals' structural connectomes in large cohort studies non-invasively. The structural connectome is initially shaped by genetics and subsequently refined by the environment.…

Applications · Statistics 2018-06-11 Zhengwu Zhang , Genevera I. Allen , Hongtu Zhu , David Dunson

Recent advances in molecular and genetic research have identified a diverse range of brain tumor sub-types, shedding light on differences in their molecular mechanisms, heterogeneity, and origins. The present study performs whole-brain…

Neurons and Cognition · Quantitative Biology 2024-07-26 Debanjali Bhattacharya , Ninad Aithal , Manish Jayswal , Neelam Sinha

Signal propagation along the structural connectome of the brain induces changes in the patterns of activity. These activity patterns define global brain states and contain information in accordance with their expected probability of…

Neurons and Cognition · Quantitative Biology 2023-03-16 Leon Weninger , Pragya Srivastava , Dale Zhou , Jason Z. Kim , Eli J. Cornblath , Maxwell A. Bertolero , Ute Habel , Dorit Merhof , Dani S. Bassett

In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

Methodology · Statistics 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

In brain connectomics, the cortical surface is parcellated into different regions of interest (ROIs) prior to statistical analysis. The brain connectome for each individual can then be represented as a graph, with the nodes corresponding to…

Methodology · Statistics 2020-10-07 Steven Winter , Zhengwu Zhang , David Dunson

Complex functional brain networks are large networks of brain regions and functional brain connections. Statistical characterizations of these networks aim to quantify global and local properties of brain activity with a small number of…

Neurons and Cognition · Quantitative Biology 2011-07-19 Mikail Rubinov , Olaf Sporns

If brain anatomy and dynamics have a genuine complex network structure as it has become standard to posit, it is also reasonable to assume that such a structure should play a key role not only in brain function but also in brain…

Neurons and Cognition · Quantitative Biology 2025-08-01 David Papo , Javier M. Buldú

Integrating brain imaging data with clinical reports offers a valuable opportunity to leverage complementary multimodal information for more effective and timely diagnosis in practical clinical settings. This approach has gained significant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Jing Zhang , Xiaowei Yu , Minheng Chen , Lu Zhang , Tong Chen , Yan Zhuang , Chao Cao , Yanjun Lyu , Li Su , Tianming Liu , Dajiang Zhu

The contribution of structural connectivity to functional brain states remains poorly understood. We present a mathematical and computational study suited to assess the structure--function issue, treating a system of Jansen--Rit neural-mass…

Neurons and Cognition · Quantitative Biology 2020-07-10 Michael Forrester , Stephen Coombes , Jonathan J. Crofts , Stamatios N. Sotiropoulos , Reuben D. O'Dea

Graph theory is now becoming a standard tool in system-level neuroscience. However, endowing observed brain anatomy and dynamics with a complex network structure does not entail that the brain actually works as a network. Asking whether the…

Neurons and Cognition · Quantitative Biology 2024-12-24 D. Papo , J. M. Buldú

With distinct advantages in power over behavioral phenotypes, brain imaging traits have become emerging endophenotypes to dissect molecular contributions to behaviors and neuropsychiatric illnesses. Among different imaging features, brain…

Applications · Statistics 2022-12-05 Yize Zhao , Changgee Chang , Jingwen Zhang , Zhengwu Zhang

Dynamic functional connectivity is an effective measure for the brain's responses to continuous stimuli. We propose an inferential method to detect the dynamic changes of brain networks based on time-varying graphical models. Whereas most…

Applications · Statistics 2020-06-23 Dingjue Ji , Junwei Lu , Yiliang Zhang , Hongyu Zhao , Siyuan Gao

Network models describe the brain as sets of nodes and edges that represent its distributed organization. So far, most discoveries in network neuroscience have prioritized insights that highlight distinct groupings and specialized…

Neurons and Cognition · Quantitative Biology 2021-05-18 Joshua Faskowitz , Richard F. Betzel , Olaf Sporns

Novel computing hardwares are necessary to keep up with today's increasing demand for data storage and processing power. In this research project, we turn to the brain for inspiration to develop novel computing substrates that are…

Neurons and Cognition · Quantitative Biology 2019-07-05 Kristine Heiney , Vibeke Devold Valderhaug , Ioanna Sandvig , Axel Sandvig , Gunnar Tufte , Hugo Lewi Hammer , Stefano Nichele

Real-world networks often benefit from capturing both local and global interactions. Inspired by multi-modal analysis in brain imaging, where structural and functional connectivity offer complementary views of network organization, we…

Neural and Evolutionary Computing · Computer Science 2025-08-11 Yang Li , Luopeiwen Yi , Tananun Songdechakraiwut

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

Neurons and Cognition · Quantitative Biology 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel
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