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The structure and dynamics of isolated nanosamples in free flight can be directly visualized via single-shot coherent diffractive imaging using the intense and short pulses of X-ray free-electron lasers. Wide-angle scattering images even…

Coherent surface scattering imaging (CSSI) is an emerging experimental technique uniquely suited to probing the structure of thin nanostructures. In these experiments, a specimen is placed on a substrate, and a series of X-ray diffraction…

Computational Physics · Physics 2026-04-22 Jeffrey J. Donatelli , Miaoqi Chu , Zixi Hu , Zhang Jiang , Nicholas Schwarz , Jin Wang , James A. Sethian

X-ray free-electron lasers (XFELs) offer unique capabilities for measuring the structure and dynamics of biomolecules, helping us understand the basic building blocks of life. Notably, high-repetition-rate XFELs enable single particle…

Computer Vision and Pattern Recognition · Computer Science 2023-12-25 Jay Shenoy , Axel Levy , Frédéric Poitevin , Gordon Wetzstein

We present a scalable and efficient framework for the inference of spatially-varying parameters of continuum materials from image observations of their deformations. Our goal is the nondestructive identification of arbitrary damage,…

Numerical Analysis · Mathematics 2024-08-21 Joseph Kirchhoff , Dingcheng Luo , Thomas O'Leary-Roseberry , Omar Ghattas

Lensless microscopy with coherent or partially coherent light sources is a well known imaging technique, commonly referred as digital in-line holographic microscopy. In the established methods, both the spatial and temporal coherence of…

Optics · Physics 2020-11-04 Sanjeev Kumar , Manjunatha Mahadevappa , Pranab Kumar Dutta

Bragg coherent x-ray diffractive imaging is a powerful technique for investigating dynamic nanoscale processes in nanoparticles immersed in reactive, realistic environments. Its temporal resolution is limited, however, by the oversampling…

Materials Science · Physics 2016-05-25 A. Ulvestad , A. Tripathi , S. O. Hruszkewycz , W. Cha , S. M. Wild , G. B. Stephenson , P. H. Fuoss

Simultaneous imaging of fluorescence-labeled and label-free phase objects in the same sample provides distinct and complementary information. Most multimodal fluorescence-phase imaging operates in transmission mode, capturing fluorescence…

Optics · Physics 2024-08-20 Renzhi He , Yucheng Li , Junjie Chen , Yi Xue

Modern Flash X-ray diffraction Imaging (FXI) acquires diffraction signals from single biomolecules at a high repetition rate from X-ray Free Electron Lasers (XFELs), easily obtaining millions of 2D diffraction patterns from a single…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Jing Liu , Stefan Engblom , Carl Nettelblad

Single-shot coherent diffractive imaging (CDI) with intense short-wavelength light pulses enables the structural characterization of individual nanoparticles in free flight with high spatial and temporal resolution. Conventional CDI assumes…

Fluorescence microscopy is a powerful tool for imaging biological samples with molecular specificity. In contrast, phase microscopy provides label-free measurement of the sample's refractive index (RI), which is an intrinsic optical…

Optics · Physics 2022-01-26 Yi Xue , David Ren , Laura Waller

We consider the non-line-of-sight (NLOS) imaging of an object using the light reflected off a diffusive wall. The wall scatters incident light such that a lens is no longer useful to form an image. Instead, we exploit the 4D spatial…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Andre Beckus , Alexandru Tamasan , George K. Atia

The accuracy of the information that can be extracted from electron diffraction patterns is often limited by the presence of optical distortions. Existing distortion characterization techniques typically require knowledge of the reciprocal…

Reconstructing the position of an interaction for any dual-phase time projection chamber (TPC) with the best precision is key to directly detecting Dark Matter. Using the likelihood-free framework, a new algorithm to reconstruct the 2-D (x;…

Instrumentation and Methods for Astrophysics · Physics 2019-03-27 U. Simola , B. Pelssers , D. Barge , J. Conrad , J. Corander

Very short pulses of x-ray free-electron lasers opened the way to obtain diffraction signal from single particles beyond the radiation dose limit. For 3D structure reconstruction many patterns are recorded in the object's unknown…

Data Analysis, Statistics and Probability · Physics 2011-05-11 Gábor Bortel , Miklós Tegze

Diffraction imaging of non-equilibrium dynamics at atomic resolution is becoming possible with X-ray free-electron lasers. However, there are unresolved problems with applying this method to objects that are confined in only one dimension.…

Strongly Correlated Electrons · Physics 2018-02-19 Kenneth R. Beyerlein

This paper addresses three-dimensional signal distortion and image reconstruction issues in x-ray Bragg coherent diffraction imaging (BCDI) in the event of a general non-orthogonal orientation of the area detector with respect to the…

Instrumentation and Detectors · Physics 2020-12-07 Siddharth Maddali , Marc Allain , Peng Li , Virginie Chamard , Stephan O. Hruszkewycz

Bin-picking of metal objects using low-cost RGB-D cameras often suffers from sparse depth information and reflective surface textures, leading to errors and the need for manual labeling. To reduce human intervention, we propose a two-stage…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Peiyuan Ni , Chee Meng Chew , Marcelo H. Ang , Gregory S. Chirikjian

One of the most powerful approaches to imaging at the nanometer or subnanometer length scale is coherent diffraction imaging using X-ray sources. For amorphous (non-crystalline) samples, the raw data can be interpreted as the modulus of the…

Numerical Analysis · Mathematics 2020-04-02 Alexander Barnett , Charles L. Epstein , Leslie Greengard , Jeremy Magland

We introduce a rapid data acquisition and reconstruction method to image the crystalline structure of materials and associated strain and orientations at micrometer resolution using Laue diffraction. Our method relies on scanning a…

Materials Science · Physics 2022-09-15 Doga Gursoy , Dina Sheyfer , Michael Wojcik , Wenjun Liu , Jonathan Z. Tischler

Interferometric closure invariants, constructed from triangular loops of mixed Fourier components, capture calibration-independent information on source morphology. While a complete set of closure invariants is directly obtainable from…

Instrumentation and Methods for Astrophysics · Physics 2024-11-20 Samuel Lai , Nithyanandan Thyagarajan , O. Ivy Wong , Foivos Diakogiannis , Lucas Hoefs
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