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We study a reaction model that presents stochastic resonance purely due to internal noise. This means that the only source of fluctuations comes from the discrete character of the reactants, and no more noises enter into the system. Our…

Statistical Mechanics · Physics 2009-11-11 Carlos Escudero

Self-induced stochastic resonance (SISR) is the emergence of coherent oscillations in slow-fast excitable systems driven solely by noise, without external periodic forcing or proximity to a bifurcation. This work presents a physics-informed…

Machine Learning · Computer Science 2026-01-29 Divyesh Savaliya , Marius E. Yamakou

Regulation of intrinsic noise in gene expression is essential for many cellular functions. Correspondingly, there is considerable interest in understanding how different molecular mechanisms of gene expression impact variations in protein…

Molecular Networks · Quantitative Biology 2011-03-02 Tao Jia , Rahul V. Kulkarni

In this paper we present a framework for investigating coloured noise in reaction-diffusion systems. We start by considering a deterministic reaction-diffusion equation and show how external forcing can cause temporally correlated or…

Quantitative Methods · Quantitative Biology 2018-12-03 Michael F Adamer , Heather A Harrington , Eamonn A Gaffney , Thomas E Woolley

We present an inequality that bounds the short-term memory capability of dynamical systems from below. It can be interpreted as an uncertainty relation between a measure of short-term memory and that of the size of state fluctuations…

Adaptation and Self-Organizing Systems · Physics 2026-05-26 Taichi Haruna , Kohei Nakajima

Speech emotion recognition (SER) often experiences reduced performance due to background noise. In addition, making a prediction on signals with only background noise could undermine user trust in the system. In this study, we propose a…

Audio and Speech Processing · Electrical Eng. & Systems 2023-09-06 Yu-Wen Chen , Julia Hirschberg , Yu Tsao

Multipotent differentiation, where cells adopt one of several cell fates, is a determinate and orchestrated procedure that often incorporates stochastic mechanisms in order to diversify cell types. How these stochastic phenomena interact to…

Cell Behavior · Quantitative Biology 2015-03-09 Andreas I. Reppas , Georgios Lolas , Andreas Deutsch , Haralampos Hatzikirou

Single-cell studies often show significant phenotypic variability due to the stochastic nature of intra-cellular biochemical reactions. When the numbers of molecules, e.g., transcription factors and regulatory enzymes, are in low abundance,…

Quantitative Methods · Quantitative Biology 2015-06-17 Kyung Hyuk Kim , Hong Qian , Herbert M. Sauro

Neuronal membrane potentials fluctuate stochastically due to conductance changes caused by random transitions between the open and close states of ion channels. Although it has previously been shown that channel noise can nontrivially…

Neurons and Cognition · Quantitative Biology 2013-12-06 Brett A. Schmerl , Mark D. McDonnell

We demonstrate the appearance of a purely entropic stochastic resonance (ESR) occurring in a geometrically confined system, where the irregular boundaries cause entropic barriers. The interplay between a periodic input signal, a constant…

Statistical Mechanics · Physics 2009-09-22 P. S. Burada , G. Schmid , D. Reguera , J. M. Rubi , P. Hänggi

Recently, the field of hardware neural networks has been actively developing, where neurons and their connections are not simulated on a computer but are implemented at the physical level, transforming the neural network into a tangible…

Neural and Evolutionary Computing · Computer Science 2026-01-14 Ivan Kolesnikov , Nadezhda Semenova

We discuss intrinsic noise effects in stochastic multiplicative-noise partial differential equations, which are qualitatively independent of the noise interpretation (Ito vs. Stratonovich), in particular in the context of noise-induced…

Statistical Mechanics · Physics 2009-11-10 O. Carrillo , M. Ibanes , J. Garcia-Ojalvo , J. Casademunt , J. M. Sancho

We study the statistical physics of a surprising phenomenon arising in large networks of excitable elements in response to noise: while at low noise, solutions remain in the vicinity of the resting state and large-noise solutions show…

Adaptation and Self-Organizing Systems · Physics 2020-04-01 Jonathan D. Touboul , Charlotte Piette , Laurent Venance , G. Bard Ermentrout

The gain of neurons' responses in the auditory cortex is sensitive to contrast changes in the stimulus within a spectrotemporal range similar to their receptive fields, which can be interpreted to represent the tuning of the input to a…

Neurons and Cognition · Quantitative Biology 2013-10-23 Linus J. Schumacher , Geoff K. Nicholls

Trial-to-trial variability is an essential feature of neural responses, but its source is a subject of active debate. Response variability (Mast and Victor, 1991; Arieli et al., 1995 & 1996; Anderson et al., 2000 & 2001; Kenet et al., 2003;…

Neurons and Cognition · Quantitative Biology 2010-08-04 L F Abbott , Kanaka Rajan , Haim Sompolinsky

After being considered as a nuisance to be filtered out, it became recently clear that biochemical noise plays a complex role, often fully functional, for a genetic network. The influence of intrinsic and extrinsic noises on genetic…

Molecular Networks · Quantitative Biology 2015-06-05 Giulio Caravagna , Giancarlo Mauri , Alberto d'Onofrio

The effects of intrinsic noise on stochastic delay systems is studied within an expansion in the inverse system size. We show that the stochastic nature of the underlying dynamics may induce oscillatory behaviour in parameter ranges where…

Molecular Networks · Quantitative Biology 2015-05-13 Tobias Galla

We investigate the behavior of a model neuron that receives a biophysically-realistic noisy post-synaptic current based on uncorrelated spiking activity from a large number of afferents. We show that, with static synapses, such noise can…

Neurons and Cognition · Quantitative Biology 2017-02-01 M. Uzuntarla , J. J. Torres , P. So , M. Ozer , E. Barreto

Cells must continuously sense and respond to time-varying environmental stimuli. These signals are transmitted and processed by biochemical signalling networks. However, the biochemical reactions making up these networks are intrinsically…

Molecular Networks · Quantitative Biology 2015-05-18 Filipe Tostevin , Pieter Rein ten Wolde

We introduce a Noise-based prior Learning (NoL) approach for training neural networks that are intrinsically robust to adversarial attacks. We find that the implicit generative modeling of random noise with the same loss function used…

Machine Learning · Computer Science 2019-06-04 Priyadarshini Panda , Kaushik Roy