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The bacterial flagellar motor drives the rotation of flagellar filaments and enables many species of bacteria to swim. Torque is generated by interaction of stator units, anchored to the peptidoglycan cell wall, with the rotor. Recent…

Subcellular Processes · Quantitative Biology 2010-08-18 G. Meacci , Y. Tu

The bacterial flagellar motor plays a crucial role in both bacterial locomotion and chemotaxis. Recent experiments reveal that the switching dynamics of the motor depends on the motor rotation speed, and thus the motor torque,…

Biological Physics · Physics 2013-07-26 Fan Bai , Tohru Minamino , Zhanghan Wu , Keiichi Namba , Jianhua Xing

The bacterial flagellar motor (BFM) is responsible for driving bacterial locomotion and chemotaxis, fundamental processes in pathogenesis and biofilm formation. In the BFM, torque is generated at the interface between transmembrane proteins…

Biological Physics · Physics 2016-02-17 Kranthi K. Mandadapu , Jasmine A. Nirody , Richard M. Berry , George Oster

Recent experiments on the bacterial flagellar motor have shown that the structure of this nanomachine, which drives locomotion in a wide range of bacterial species, is more dynamic than previously believed. Specifically, the number of…

Biological Physics · Physics 2016-08-24 Jasmine A. Nirody , Richard M. Berry , George Oster

Rotation of a single bacterial flagellar motor is powered by multiple stators tethered to the cell wall. In a "power-stroke" model the observed independence of the speed at low load on the number of stators is explained by a…

Subcellular Processes · Quantitative Biology 2010-08-16 Giovanni Meacci , Ganhui Lan , Yuhai Tu

Many swimming bacteria are propelled by flagellar motors that stochastically switch between the clockwise and counterclockwise rotation direction. While the switching dynamics are one of the most important characteristics of flagellar…

Subcellular Processes · Quantitative Biology 2008-11-18 Siebe B. van Albada , Sorin Tanase-Nicola , Pieter Rein ten Wolde

Bacterial flagellar motor is one of the most complex and sophisticated nano machineries in nature. A duty ratio $D$ is a fraction of time that the stator and the rotor interact and is a fundamental property to characterize the motor but…

Biological Physics · Physics 2019-06-26 Kento Sato , Shuichi Nakamura , Seishi Kudo , Shoichi Toyabe

Bacterial flagellar motor (BFM) is one of the ion-driven molecular machines, which drives the rotation of flagellar filaments and enable bacteria to swim in viscous solutions. Understanding its mechanism is one challenge in biophysics.…

Biological Physics · Physics 2015-03-06 Yunxin Zhang

The bacterial flagellar motor (BFM) is a rotary molecular machine driven by the ion electrochemical potential across the cell membrane. Recent cryo-EM structures reveal a cogwheel-like architecture in which multiple stators engage a large…

Biological Physics · Physics 2026-04-02 Jiading Zhu , Yongnan Hu , Yuhai Tu , Yuansheng Cao

Many bacteria are motile by means of one or more rotating rigid helical flagella, making them the only known organism to use rotation as a means of propulsion. The rotation is supplied by the bacterial flagellar motor, a particularly…

In this article, we develop a mathematical model for the rotary bacterial flagellar motor (BFM) based on the recently discovered structure of the stator complex (MotA$_5$MotB$_2$). The structure suggested that the stator also rotates. The…

Soft Condensed Matter · Physics 2022-02-15 Yuansheng Cao , Tairan Li , Yuhai Tu

Flagellar motors enable bacteria to navigate their environments by switching rotation direction in response to external cues with high sensitivity. Previous work suggested that ultrasensitivity of the flagellar motor originates from…

Biological Physics · Physics 2025-02-06 Henry H. Mattingly , Yuhai Tu

A tiny bacterial flagellar motor rotates in both counter-clockwise (CCW) and clockwise (CW) rotational directions. The most important measurable characteristic of the flagellar motor is its torque versus angular speed relationship in CCW or…

Biological Physics · Physics 2021-09-07 Biswajit Das , Hao Ge

Many types of bacteria swim by rotating a bundle of helical filaments also called flagella. Each filament is driven by a rotary motor and a very flexible hook transmits the motor torque to the filament. We model it by discretizing…

Biological Physics · Physics 2012-01-04 Reinhard Vogel , Holger Stark

The bacterial flagellar motor (BFM) converts transmembrane ion flux into directed mechanical rotation, driving bacterial motility. Despite extensive study, the frictional forces and energetics governing its torque generation remain poorly…

Biological Physics · Physics 2025-12-18 N. J. Lopez-Alamilla , A. L. Nord , F. Pedaci , J. Palmeri , N. -O. Walliser

Recent advances in microscopy techniques has uncovered unique aspects of flagella-driven motility in bacteria. A remarkable example is the discovery of flagellar wrapping, a phenomenon whereby a bacterium wraps its flagellum (or flagellar…

Soft Condensed Matter · Physics 2025-04-22 Takuro Kataoka , Taiju Yoneda , Daisuke Nakane , Hirofumi Wada

In this supporting information we briefly describe the torque-speed measurement procedure. We show the hook spring compliance used in the simulations. We analyze the distribution functions of the moving and waiting time intervals. We study…

Subcellular Processes · Quantitative Biology 2010-08-18 G. Meacci , Y. Tu

The bacterial flagellar motor is a highly efficient rotary machine used by many bacteria to propel themselves. It has recently been shown that at low speeds its rotation proceeds in steps [Sowa et al. (2005) Nature 437, 916--919]. Here we…

Biological Physics · Physics 2009-10-25 Thierry Mora , Howard Yu , Yoshiyuki Sowa , Ned S. Wingreen

Numerous studies have explored the link between bacterial swimming and the number of flagella, a distinguishing feature of motile multiflagellated bacteria. We revisit this open question using augmented slender-body theory simulations, in…

Biological Physics · Physics 2024-09-04 Maria Tătulea-Codrean , Eric Lauga

The cooperative binding of molecular agents onto a substrate is pervasive in living systems. To study whether a system shows cooperativity, one can rely on a fluctuation analysis of quantities such as the number of substrate-bound units and…

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