Related papers: A generalized kinetic framework applied to whole-c…
Flow-matching generative models are increasingly used to simulate cell responses to biological perturbations. However, the design space for building such models is large and underexplored. We systematically analyse the design space of flow…
A stochastic model is used to assess the effect of external parameters on the development of submerged biofilms on smooth and rough surfaces. The model includes basic cellular mechanisms, such as division and spreading, together with an…
Mean force kinetic theory is used to evaluate the electrical conductivity, thermal conductivity, electrothermal coefficient, thermoelectric coefficient, and shear viscosity of a two-component (ion-electron) plasma. Results are compared with…
Due to evergrowing importance of understanding flow of bio-fluids in Lab-on-CD based systems, we investigate the flow behaviour of power-law fluids in the rotating electroosmotic flow through a polyelectrolyte grafted (soft) narrow channel.…
Biomolecular machines transduce between different forms of energy. These machines make directed progress and increase their speed by consuming free energy, typically in the form of nonequilibrium chemical concentrations. Machine dynamics…
We study the effect of restart, and retry, on the mean completion time of a generic process. The need to do so arises in various branches of the sciences and we show that it can naturally be addressed by taking advantage of the classical…
Accurate measurements of kinetic rate constants for interacting biomolecules is crucial for understanding the mechanisms underlying intracellular signalling pathways. The magnitude of binding rates plays a very important molecular…
Cryo-electron microscopy (cryo-EM) is a powerful technique in structural biology and drug discovery, enabling the study of biomolecules at high resolution. Significant advancements by structural biologists using cryo-EM have led to the…
We introduce a closure model for wall-modeled large-eddy simulation (WMLES), referred to as the Building-block Flow Model (BFM). The foundation of the model rests on the premise that a finite collection of simple flows encapsulates the…
Reduced models for approximating the impact of kinetic electron behavior on the transport of thermal energy and magnetic field are investigated. The thermal flux limiter has improved agreement with Vlasov-Fokker-Planck data when a harmonic…
A general framework for the simulation of reaction-diffusion systems with probabilistic cellular automata is presented. The basic reaction probabilities of the chemical model translate directly into the transition rules of the automaton,…
Ultrafast electron microscopy (UEM) has found widespread applications in physics, chemistry, and materials science, enabling real-space imaging of dynamics on ultrafast timescales. Recent advances have pushed the temporal resolution of UEM…
We derive a single-cell level understanding of metabolism in an isogenic cyanobacterial population by integrating secondary ion mass spectrometry (SIMS) derived multi-isotope uptake measurements of Synechocystis sp. PCC6803 with a…
The hydrodynamic limit of a one dimensional kinetic model describing chemotaxis is investigated. The limit system is a conservation law coupled to an elliptic problem for which the macroscopic velocity is possibly discontinuous. Therefore,…
This work proposes to use evolutionary computation as a pathway to allow a new perspective on the modeling of energy expenditure and recovery of an individual athlete during exercise. We revisit a theoretical concept called the "three…
Catalytic microswimmers typically swim close to walls due to hydrodynamic and/or phoretic effects. The walls in turn are known to affect their propulsion, making it difficult to single out the contributions that stem from particle-based…
A new CLIC Test Facility (CTF3) at CERN will serve to study the drive beam generation for the Compact Linear Collider (CLIC). CTF3 has to accelerate a 3.5 A electron beam in almost fully-loaded structures. The pulse contains more than 2000…
The symmetry breaking of the actin network from radial to longitudinal symmetry has been identified as the major mechanism for keratocytes (fish cells) motility on solid substrate. For strong friction coefficient, the two dimensional actin…
An innovative path for the detectors at future colliders to achieve higher performances is to use a Particle Flow approach, which requires highly granular calorimeters to image individual showers. The silicon-tungsten electromagnetic…
Particle image velocimetry (PIV) and related optical-flow methods are widely used to quantify fluid motion, but their development and evaluation are often hindered by fragmented software, inconsistent interfaces, and limited…