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Metabolic disorders, particularly type 2 diabetes mellitus (T2DM), represent a significant global health burden, disproportionately impacting genetically predisposed populations such as the Pima Indians (a Native American tribe from south…

Machine Learning · Computer Science 2025-09-24 Iram Wajahat , Amritpal Singh , Fazel Keshtkar , Syed Ahmad Chan Bukhari

Mental health conditions cause a great deal of distress or impairment; depression alone will affect 11% of the world's population. The application of Artificial Intelligence (AI) and big-data technologies to mental health has great…

We propose a prognostic stratum matching framework that addresses the deficiencies of Randomized trial data subgroup analysis and transforms ObservAtional Data to be used as if they were randomized, thus paving the road for precision…

Applications · Statistics 2023-11-06 Dimitris Bertsimas , Angelos G. Koulouras , Georgios Antonios Margonis

Introduction: Chronic pain patients are at increased risk of opioid-misuse. Less is known about the unique risk conferred by each pain-management treatment, as treatments are typically implemented together, confounding their independent…

Over 30 million Americans are affected by Type II diabetes (T2D), a treatable condition with significant health risks. This study aims to develop and validate predictive models using machine learning (ML) techniques to estimate emergency…

Quantitative Methods · Quantitative Biology 2024-12-13 Javad M Alizadeh , Jay S Patel , Gabriel Tajeu , Yuzhou Chen , Ilene L Hollin , Mukesh K Patel , Junchao Fei , Huanmei Wu

The management of hyperglycemia in hospitalized patients has a significant impact on both morbidity and mortality. Therefore, it is important to predict the need for diabetic patients to be hospitalized. However, using standard machine…

Artificial Intelligence · Computer Science 2022-08-02 Shaina Raza

The aim of this study is to look at predicting whether a person will complete a drug and alcohol rehabilitation program and the number of times a person attends. The study is based on demographic data obtained from Substance Abuse and…

Machine Learning · Computer Science 2024-04-25 Karen Roberts-Licklider , Theodore Trafalis

Background. Real-world data show that approximately 50% of psoriasis patients treated with a biologic agent will discontinue the drug because of loss of efficacy. History of previous therapy with another biologic, female sex and obesity…

Machine Learning · Statistics 2019-08-27 Sepideh Emam , Amy X. Du , Philip Surmanowicz , Simon F. Thomsen , Russ Greiner , Robert Gniadecki

Augmentation of disease diagnosis and decision-making in healthcare with machine learning algorithms is gaining much impetus in recent years. In particular, in the current epidemiological situation caused by COVID-19 pandemic, swift and…

Computers and Society · Computer Science 2021-02-23 Leopold Franz , Yash Raj Shrestha , Bibek Paudel

Efficient resource allocation is a key challenge in modern cloud computing. Over-provisioning leads to unnecessary costs, while under-provisioning risks performance degradation and SLA violations. This work presents an artificial…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-08 Harshit Goyal

Torsades de pointes (TdP) is an irregular heart rhythm characterized by faster beat rates and potentially could lead to sudden cardiac death. Much effort has been invested in understanding the drug-induced TdP in preclinical studies.…

Applications · Statistics 2022-01-10 Nan Milex Xi , Yu-Yi Hsu , Qianyu Dang , Dalong Patrick Huang

We ascertain and compare the performances of AutoML tools on large, highly imbalanced healthcare datasets. We generated a large dataset using historical administrative claims including demographic information and flags for disease codes in…

The rising rate of drug-related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free-text coroner reports, leading to delays and…

Real-World Data (RWD), with its large sample sizes and rich clinical detail, offers a compelling alternative to randomized controlled trials (RCTs) for studying treatment effects in diverse and complex patient populations. However, its…

Applications · Statistics 2026-05-26 Yifei Xu , Hwiyoung Lee , Zhenyao Ye , Yezhi Pan , Jingsong Zhou , Yun Yang , Chixiang Chen , Shuo Chen

Heart disease continues to pose a critical worldwide health issue, more specifically in areas with insufficient access to healthcare infrastructure and diagnostic systems. Conventional diagnostic approaches often fall short in accurately…

Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the opioid crisis. The relationship between substance use and mental health has been extensively studied, with one possible relationship being…

Artificial Intelligence · Computer Science 2021-03-30 Usha Lokala , Francois Lamy , Triyasha Ghosh Dastidar , Kaushik Roy , Raminta Daniulaityte , Srinivasan Parthasarathy , Amit Sheth

An estimated 300 million people worldwide suffer from asthma, and this number is expected to increase to 400 million by 2025. Approximately 250,000 people die prematurely each year from asthma out of which, almost all deaths are avoidable.…

Computers and Society · Computer Science 2018-04-13 Saksham Kukreja

In the context of personalized medicine, machine learning algorithms are growing in popularity. These algorithms require substantial information, which can be acquired effectively through the usage of previously gathered data. Open data and…

Machine Learning · Computer Science 2026-01-13 Niklas Jacobs , Manuel C. Voelkle , Norbert Kathmann , Kevin Hilbert

Problem Definition. Increasing costs of healthcare highlight the importance of effective disease prevention. However, decision models for allocating preventive care are lacking. Methodology/Results. In this paper, we develop a data-driven…

Machine Learning · Computer Science 2023-08-15 Mathias Kraus , Stefan Feuerriegel , Maytal Saar-Tsechansky

Problem definition: Access to accurate predictions of patients' outcomes can enhance medical staff's decision-making, which ultimately benefits all stakeholders in the hospitals. A large hospital network in the US has been collaborating…