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We consider the problem of estimating fold-changes in the expected value of a multivariate outcome observed with unknown sample-specific and category-specific perturbations. This challenge arises in high-throughput sequencing studies of the…

Methodology · Statistics 2026-04-24 David S Clausen , Sarah Teichman , Amy D Willis

A Support Vector Method for multivariate performance measures was recently introduced by Joachims (2005). The underlying optimization problem is currently solved using cutting plane methods such as SVM-Perf and BMRM. One can show that these…

Machine Learning · Computer Science 2012-02-20 Xinhua Zhang , Ankan Saha , S. V. N. Vishwanatan

This paper develops an empirical balancing approach for the estimation of treatment effects under two-sided noncompliance using a binary conditionally independent instrumental variable. The method weighs both treatment and outcome…

Econometrics · Economics 2020-07-10 Phillip Heiler

Balancing weights have been widely applied to single or monotone missingness due to empirical advantages over likelihood-based methods and inverse probability weighting approaches. This paper considers non-monotone missing data under the…

Methodology · Statistics 2024-12-13 Jianing Dong , Raymond K. W. Wong , Kwun Chuen Gary Chan

This paper considers the problem of estimating a high-dimensional vector of parameters $\boldsymbol{\theta} \in \mathbb{R}^n$ from a noisy observation. The noise vector is i.i.d. Gaussian with known variance. For a squared-error loss…

Information Theory · Computer Science 2018-03-19 K. Pavan Srinath , Ramji Venkataramanan

Much of the focus in machine learning research is placed in creating new architectures and optimization methods, but the overall loss function is seldom questioned. This paper interprets machine learning from a multi-objective optimization…

Machine Learning · Statistics 2015-07-22 Conrado Silva Miranda , Fernando José Von Zuben

For some estimations and predictions, we solve minimization problems with asymmetric loss functions. Usually, we estimate the coefficient of regression for these problems. In this paper, we do not make such the estimation, but rather give a…

Statistics Theory · Mathematics 2023-03-03 Naoya Yamaguchi , Yuka Yamaguchi , Ryuei Nishii

The paper concerns foundations of sensitivity and stability analysis in optimization and related areas, being primarily addressed truncated constrained systems. We consider general models, which are described by multifunctions between…

Optimization and Control · Mathematics 2025-04-30 Boris S. Mordukhovich , Pengcheng Wu , Xiaoqi Yang

Let $\pi_1$ and $\pi_2$ be two independent populations, where the population $\pi_i$ follows a bivariate normal distribution with unknown mean vector $\boldsymbol{\theta}^{(i)}$ and common known variance-covariance matrix $\Sigma$, $i=1,2$.…

Statistics Theory · Mathematics 2024-08-29 Mohd. Arshad , Omer Abdalghani , Kalu Ram Meena

In a remarkable series of papers beginning in 1956, Charles Stein set the stage for the future development of minimax shrinkage estimators of a multivariate normal mean under quadratic loss. More recently, parallel developments have seen…

Methodology · Statistics 2012-03-27 Edward I. George , Feng Liang , Xinyi Xu

Estimating time-varying correlation matrices is challenging because existing methods may adapt slowly to structural changes, impose insufficient regularization, or produce diffuse posterior uncertainty. In moderate dimensions, an additional…

Methodology · Statistics 2026-05-11 Daniel Andrew Coulson , David S. Matteson , Martin T. Wells

This paper reviews advances in Stein-type shrinkage estimation for spherically symmetric distributions. Some emphasis is placed on developing intuition as to why shrinkage should work in location problems whether the underlying population…

Methodology · Statistics 2012-03-22 Ann Cohen Brandwein , William E. Strawderman

We consider a high-dimensional mean estimation problem over a binary hidden Markov model, which illuminates the interplay between memory in data, sample size, dimension, and signal strength in statistical inference. In this model, an…

Statistics Theory · Mathematics 2022-10-13 Yihan Zhang , Nir Weinberger

The main result of this article is that we obtain an elementwise error bound for the Fused Lasso estimator for any general convex loss function $\rho$. We then focus on the special cases when either $\rho$ is the square loss function (for…

Statistics Theory · Mathematics 2022-03-21 Teng Zhang , Sabyasachi Chatterjee

We introduce a tunable loss function called $\alpha$-loss, parameterized by $\alpha \in (0,\infty]$, which interpolates between the exponential loss ($\alpha = 1/2$), the log-loss ($\alpha = 1$), and the 0-1 loss ($\alpha = \infty$), for…

Machine Learning · Computer Science 2022-12-22 Tyler Sypherd , Mario Diaz , John Kevin Cava , Gautam Dasarathy , Peter Kairouz , Lalitha Sankar

Suppose that a target function is monotonic, namely, weakly increasing, and an available original estimate of this target function is not weakly increasing. Rearrangements, univariate and multivariate, transform the original estimate to a…

Statistics Theory · Mathematics 2018-01-08 Victor Chernozhukov , Ivan Fernandez-Val , Alfred Galichon

Comparison data arises in many important contexts, e.g. shopping, web clicks, or sports competitions. Typically we are given a dataset of comparisons and wish to train a model to make predictions about the outcome of unseen comparisons. In…

Machine Learning · Statistics 2018-07-25 Stephen Ragain , Alexander Peysakhovich , Johan Ugander

We propose a mathematical model that combines elastic, viscous and porous effects with growth or shrinkage due to microstructural changes. This phenomenon is important in tissue or tumor growth, as well as in dermal contraction. Although…

Numerical Analysis · Mathematics 2025-12-12 Sabia Asghar , Duncan den Bakker , Etelvina Javierre , Qiyao Peng , Fred J. Vermolen

In a coherent reliability system composed of multiple components configured according to a specific structure function, the distribution of system time to failure, or system lifetime, is often of primary interest. Accurate estimation of…

Methodology · Statistics 2025-09-19 Beidi Qiang , Edsel Pena

It is a well known fact that recovery rates tend to go down when the number of defaults goes up in economic downturns. We demonstrate how the loss given default model with the default and recovery dependent via the latent systematic risk…

Risk Management · Quantitative Finance 2014-11-03 Xiaolin Luo , Pavel V. Shevchenko