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This article presents the general framework of theranostic digital twins (TDTs) in computational nuclear medicine, designed to support clinical decision-making and improve cancer patient prognosis through personalized radiopharmaceutical…

Other Quantitative Biology · Quantitative Biology 2025-11-07 Marc Ryhiner , Yangmeihui Song , Babak Saboury , Gerhard Glatting , Arman Rahmim , Kuangyu Shi

To reproduce eScience, several challenges need to be solved: scientific workflows need to be automated; the involved software versions need to be provided in an unambiguous way; input data needs to be easily accessible; High-Performance…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-01-30 Kessy Abarenkov , Anne Fouilloux , Helmut Neukirchen , Abdulrahman Azab

Trinity-RFT is a general-purpose, unified and easy-to-use framework designed for reinforcement fine-tuning (RFT) of large language models. It is built with a modular and decoupled design, consisting of (1) an RFT-core that unifies and…

Software is the key crosscutting technology that enables advances in mathematics, computer science, and domain-specific science and engineering to achieve robust simulations and analysis for science, engineering, and other research fields.…

An increasing number of researchers support reproducibility by including pointers to and descriptions of datasets, software and methods in their publications. However, scientific articles may be ambiguous, incomplete and difficult to…

Building software that can support the huge growth in data and computation required by modern research needs individuals with increasingly specialist skill sets that take time to develop and maintain. The Research Software Engineering…

Software Engineering · Computer Science 2023-01-26 J. Cohen , D. S. Katz , M. Barker , N. Chue Hong , R. Haines , C. Jay

How should software engineering be adapted for Computational Science (CS)? If we understood that, then we could better support software sustainability, verifiability, reproducibility, comprehension, and usability for CS community. For…

Software Engineering · Computer Science 2020-03-13 Huy Tu , Rishabh Agrawal , Tim Menzies

Internet-scale distributed systems often replicate data at multiple geographic locations to provide low latency and high availability, despite node and network failures. Geo-replicated systems that adopt a weak consistency model allow…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-06-28 Nuno Preguiça

Citiverses hold the potential to support regulatory learning by offering immersive, virtual environments for experimenting with policy scenarios and technologies. This paper proposes a science-for-policy agenda to explore the potential of…

Artificial Intelligence · Computer Science 2025-10-21 Isabelle Hupont , Marisa Ponti , Sven Schade

Research software refers to software development tools that accelerate discovery and simplifies access to digital infrastructures. However, although research software platforms can be built increasingly more innovative and powerful than…

Software Engineering · Computer Science 2018-12-27 Doug Mulholland , Paulo Alencar , Donald Cowan

An essential part of research and scientific communication is researchers' ability to reproduce the results of others. While there have been increasing standards for authors to make data and code available, many of these files are hard to…

Digital Libraries · Computer Science 2021-09-23 Layan Bahaidarah , Ethan Hung , Andreas F. De Melo Oliveira , Jyotsna Penumaka , Lukas Rosario , Ana Trisovic

Many systems can be described in terms of networks of discrete elements and their various relationships to one another. A semantic network, or multi-relational network, is a directed labeled graph consisting of a heterogeneous set of…

Artificial Intelligence · Computer Science 2008-11-03 Marko A. Rodriguez , Jennifer H. Watkins , Johan Bollen , Carlos Gershenson

Software plays a central role in scientific discovery. Improving how we develop and use software for research can have both broad and deep impacts on a spectrum of challenges and opportunities society faces today. The emergence of Research…

Software Engineering · Computer Science 2022-11-17 Michael A. Heroux

In this paper, we present a new R package COREclust dedicated to the detection of representative variables in high dimensional spaces with a potentially limited number of observations. Variable sets detection is based on an original graph…

Mathematical Software · Computer Science 2018-05-28 Camille Champion , Anne-Claire Brunet , Jean-Michel Loubes , Laurent Risser

Robotic systems are multi-dimensional entities, combining both hardware and software, that are heavily dependent on, and influenced by, interactions with the real world. They can be variously categorised as embedded, cyberphysical,…

Software Engineering · Computer Science 2018-09-05 Marie Farrell , Matt Luckcuck , Michael Fisher

Quantum cryptographic technology (QCT) is expected to be a fundamental technology for realizing long-term information security even against as-yet-unknown future technologies. More advanced security could be achieved using QCT together with…

CRDTs are distributed data types that make eventual consistency of a distributed object possible and non ad-hoc. Specifically, state-based CRDTs ensure convergence through disseminating the en- tire state, that may be large, and merging it…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-03-04 Paulo Sérgio Almeida , Ali Shoker , Carlos Baquero

In this paper we present tools for applied researchers that re-purpose off-the-shelf methods from the computer-science field of machine learning to create a "discovery engine" for data from randomized controlled trials (RCTs). The applied…

Machine Learning · Statistics 2019-05-13 Jens Ludwig , Sendhil Mullainathan , Jann Spiess

In-materia reservoir computing (RC) leverages the intrinsic physical responses of functional materials to perform complex computational tasks. Magnetic metamaterials are exciting candidates for RC due to their huge state space, nonlinear…

With the growing complexity and capability of contemporary robotic systems, the necessity of sophisticated computing solutions to efficiently handle tasks such as real-time processing, sensor integration, decision-making, and control…

Robotics · Computer Science 2025-09-09 Md Rafid Islam