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In this paper, we propose generating synthetic multiple sclerosis (MS) lesions on MRI images with the final aim to improve the performance of supervised machine learning algorithms, therefore avoiding the problem of the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2019-01-18 Mostafa Salem , Sergi Valverde , Mariano Cabezas , Deborah Pareto , Arnau Oliver , Joaquim Salvi , Àlex Rovira , Xavier Lladó

Monitoring treatment response in longitudinal studies plays an important role in clinical practice. Accurately identifying lesions across serial imaging follow-up is the core to the monitoring procedure. Typically this incorporates both…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Jinzheng Cai , Youbao Tang , Ke Yan , Adam P. Harrison , Jing Xiao , Gigin Lin , Le Lu

Multiple Sclerosis (MS) is a chronic neurological condition characterized by the development of lesions in the white matter of the brain. T2-fluid attenuated inversion recovery (FLAIR) brain magnetic resonance imaging (MRI) provides…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Jueqi Wang , Derek Berger , Erin Mazerolle , Jean-Alexis Delamer , Jacob Levman

Multiple sclerosis is an inflammatory disorder of the central nervous system. Quantitative MRI has huge potential to provide intrinsic and normative values of tissue properties useful for diagnosis, prognosis and ultimately clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-03 Haykel Snoussi , Julien Cohen-Adad , Benoit Combes , Elise Bannier , Slimane Tounekti , Anne Kerbrat , Christian Barillot , Emmanuel Caruyer

Lesion counts are important indicators of disease severity, patient prognosis, and treatment efficacy, yet counting as a task in medical imaging is often overlooked in favor of segmentation. This work introduces a novel continuously…

Image and Video Processing · Electrical Eng. & Systems 2022-05-13 Julien Schroeter , Chelsea Myers-Colet , Douglas L Arnold , Tal Arbel

Lesion volume is an important predictor for prognosis in breast cancer. We make a step towards a more accurate lesion volume measurement on digital mammograms by developing a model that allows to estimate lesion volumes on processed…

Segmenting healthy tissue structures alongside lesions in brain Magnetic Resonance Images (MRI) remains a challenge for today's algorithms due to lesion-caused disruption of the anatomy and lack of jointly labeled training datasets, where…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Meva Himmetoglu , Ilja Ciernik , Ender Konukoglu

The evaluation of white matter lesion progression is an important biomarker in the follow-up of MS patients and plays a crucial role when deciding the course of treatment. Current automated lesion segmentation algorithms are susceptible to…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Mattias Billast , Maria Ines Meyer , Diana M. Sima , David Robben

Early detection and segmentation of skin lesions is crucial for timely diagnosis and treatment, necessary to improve the survival rate of patients. However, manual delineation is time consuming and subject to intra- and inter-observer…

Computer Vision and Pattern Recognition · Computer Science 2019-02-26 Sulaiman Vesal , Shreyas Malakarjun Patil , Nishant Ravikumar , Andreas Maier

Accurate brain lesion delineation is important for planning neurosurgical treatment. Automatic brain lesion segmentation methods based on convolutional neural networks have demonstrated remarkable performance. However, neural network…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Jiayu Huo , Sebastien Ourselin , Rachel Sparks

In this paper, an automatic algorithm aimed at volumetric segmentation of acute ischemic stroke lesion in non-contrast computed tomography brain 3D images is proposed. Our deep-learning approach is based on the popular 3D U-Net…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 A. V. Dobshik , S. K. Verbitskiy , I. A. Pestunov , K. M. Sherman , Yu. N. Sinyavskiy , A. A. Tulupov , V. B. Berikov

Identifying, measuring and reporting lesions accurately and comprehensively from patient CT scans are important yet time-consuming procedures for physicians. Computer-aided lesion/significant-findings detection techniques are at the core of…

Computer Vision and Pattern Recognition · Computer Science 2020-09-01 Jinzheng Cai , Ke Yan , Chi-Tung Cheng , Jing Xiao , Chien-Hung Liao , Le Lu , Adam P. Harrison

Finding automatically multiple lesions in large images is a common problem in medical image analysis. Solving this problem can be challenging if, during optimization, the automated method cannot access information about the location of the…

Computer Vision and Pattern Recognition · Computer Science 2020-03-23 Florian Dubost , Hieab Adams , Pinar Yilmaz , Gerda Bortsova , Gijs van Tulder , M. Arfan Ikram , Wiro Niessen , Meike Vernooij , Marleen de Bruijne

Technology aided platforms provide reliable tools in almost every field these days. These tools being supported by computational power are significant for applications that need sensitive and precise data analysis. One such important…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Muhammad Ali Farooq , Muhammad Aatif Mobeen Azhar , Rana Hammad Raza

This paper explores the use of a soft ground-truth mask ("soft mask'') to train a Fully Convolutional Neural Network (FCNN) for segmentation of Multiple Sclerosis (MS) lesions. Detection and segmentation of MS lesions is a complex task…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Eytan Kats , Jacob Goldberger , Hayit Greenspan

The accurate assessment of White matter hyperintensities (WMH) burden is of crucial importance for epidemiological studies to determine association between WMHs, cognitive and clinical data. The manual delineation of WMHs is tedious, costly…

Tissues and Organs · Quantitative Biology 2018-01-03 R. Guerrero , C. Qin , O. Oktay , C. Bowles , L. Chen , R. Joules , R. Wolz , M. C. Valdes-Hernandez , D. A. Dickie , J. Wardlaw , D. Rueckert

Facial analysis has emerged as a prominent area of research with diverse applications, including cosmetic surgery programs, the beauty industry, photography, and entertainment. Manipulating patient images often necessitates professional…

Image and Video Processing · Electrical Eng. & Systems 2024-02-14 Reza Sarshar , Mohammad Heydari , Elham Akhondzadeh Noughabi

This paper presents a simple and effective generalization method for magnetic resonance imaging (MRI) segmentation when data is collected from multiple MRI scanning sites and as a consequence is affected by (site-)domain shifts. We propose…

Image and Video Processing · Electrical Eng. & Systems 2019-10-23 Shahab Aslani , Vittorio Murino , Michael Dayan , Roger Tam , Diego Sona , Ghassan Hamarneh

Understanding the intensity characteristics of brain lesions is key for defining image-based biomarkers in neurological studies and for predicting disease burden and outcome. In this work, we present a novel foreground-based generative…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Berke Doga Basaran , Mengyun Qiao , Paul M. Matthews , Wenjia Bai

Multiple sclerosis (MS) expresses substantial clinical and radiological heterogeneity, which poses significant challenges for automatic lesion segmentation. The current deep learning-based SOTA is highly susceptible to changes in both…

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