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Optical microscopy is an essential tool in biology and medicine. Imaging thin, yet non-flat objects in a single shot (without relying on more sophisticated sectioning setups) remains challenging as the shallow depth of field that comes with…

Image and Video Processing · Electrical Eng. & Systems 2020-10-14 Adrian Shajkofci , Michael Liebling

Deconvolution microscopy has been extensively used to improve the resolution of the wide-field fluorescent microscopy, but the performance of classical approaches critically depends on the accuracy of a model and optimization algorithms.…

Image and Video Processing · Electrical Eng. & Systems 2020-07-09 Sungjun Lim , Hyoungjun Park , Sang-Eun Lee , Sunghoe Chang , Jong Chul Ye

We present a semi-blind, spatially-variant deconvolution technique aimed at optical microscopy that combines a local estimation step of the point spread function (PSF) and deconvolution using a spatially variant, regularized Richardson-Lucy…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Adrian Shajkofci , Michael Liebling

Deconvolution is the most commonly used image processing method to remove the blur caused by the point-spread-function (PSF) in optical imaging systems. While this method has been successful in deblurring, it suffers from several…

Image and Video Processing · Electrical Eng. & Systems 2019-10-10 Huangxuan Zhao , Ziwen Ke , Ningbo Chen , Ke Li , Lidai Wang , Xiaojing Gong , Wei Zheng , Liang Song , Zhicheng Liu , Dong Liang , Chengbo Liu

Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

Computer Vision and Pattern Recognition · Computer Science 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

Recent deep monocular depth estimation approaches based on supervised regression have achieved remarkable performance. However, they require costly ground truth annotations during training. To cope with this issue, in this paper we present…

Computer Vision and Pattern Recognition · Computer Science 2019-09-18 Andrea Pilzer , Stéphane Lathuilière , Dan Xu , Mihai Marian Puscas , Elisa Ricci , Nicu Sebe

Existing video super-resolution (SR) algorithms usually assume that the blur kernels in the degradation process are known and do not model the blur kernels in the restoration. However, this assumption does not hold for video SR and usually…

Computer Vision and Pattern Recognition · Computer Science 2020-03-11 Jinshan Pan , Songsheng Cheng , Jiawei Zhang , Jinhui Tang

Very deep convolutional neural networks (CNNs) have been firmly established as the primary methods for many computer vision tasks. However, most state-of-the-art CNNs are large, which results in high inference latency. Recently, depth-wise…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Yihui He , Jianing Qian , Jianren Wang , Cindy X. Le , Congrui Hetang , Qi Lyu , Wenping Wang , Tianwei Yue

We present a new method for blind motion deblurring that uses a neural network trained to compute estimates of sharp image patches from observations that are blurred by an unknown motion kernel. Instead of regressing directly to patch…

Computer Vision and Pattern Recognition · Computer Science 2016-08-02 Ayan Chakrabarti

Many microscopy applications are limited by the total amount of usable light and are consequently challenged by the resulting levels of noise in the acquired images. This problem is often addressed via (supervised) deep learning based…

Image and Video Processing · Electrical Eng. & Systems 2020-08-20 Anna S. Goncharova , Alf Honigmann , Florian Jug , Alexander Krull

Deep neural networks have been applied to improve the image quality of fluorescence microscopy imaging. Previous methods are based on convolutional neural networks (CNNs) which generally require more time-consuming training of separate…

Instrumental aberrations strongly limit high-contrast imaging of exoplanets, especially when they produce quasistatic speckles in the science images. With the help of recent advances in deep learning, we have developed in previous works an…

Instrumentation and Methods for Astrophysics · Physics 2022-11-14 Maxime Quesnel , Gilles Orban de Xivry , Olivier Absil , Gilles Louppe

Fluorescence microscopy plays an important role in biomedical research. The depth-variant point spread function (PSF) of a fluorescence microscope produces low-quality images especially in the out-of-focus regions of thick specimens.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-09 Da He , De Cai , Jiasheng Zhou , Jiajia Luo , Sung-Liang Chen

In computer-aided diagnosis (CAD) focused on microscopy, denoising improves the quality of image analysis. In general, the accuracy of this process may depend both on the experience of the microscopist and on the equipment sensitivity and…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Fabio Hernán Gil Zuluaga , Francesco Bardozzo , Jorge Iván Ríos Patiño , Roberto Tagliaferri

Compressive sensing (CS), aiming to reconstruct an image/signal from a small set of random measurements has attracted considerable attentions in recent years. Due to the high dimensionality of images, previous CS methods mainly work on…

Computer Vision and Pattern Recognition · Computer Science 2018-02-01 Xiaotong Lu , Weisheng Dong , Peiyao Wang , Guangming Shi , Xuemei Xie

Blind inpainting algorithms based on deep learning architectures have shown a remarkable performance in recent years, typically outperforming model-based methods both in terms of image quality and run time. However, neural network…

Computer Vision and Pattern Recognition · Computer Science 2022-05-16 Jenny Schmalfuss , Erik Scheurer , Heng Zhao , Nikolaos Karantzas , Andrés Bruhn , Demetrio Labate

Image denoising is an essential part of many image processing and computer vision tasks due to inevitable noise corruption during image acquisition. Traditionally, many researchers have investigated image priors for the denoising, within…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Jae Woong Soh , Nam Ik Cho

Blind deconvolution is a challenging problem, but in low-light it is even more difficult. Existing algorithms, both classical and deep-learning based, are not designed for this condition. When the photon shot noise is strong, conventional…

Image and Video Processing · Electrical Eng. & Systems 2022-11-21 Yash Sanghvi , Abhiram Gnanasambandam , Zhiyuan Mao , Stanley H. Chan

Objective: To simultaneously deblur and supersample prostate specific membrane antigen (PSMA) positron emission tomography (PET) images using neural blind deconvolution. Approach: Blind deconvolution is a method of estimating the…

Medical Physics · Physics 2024-04-11 Caleb Sample , Arman Rahmim , Carlos Uribe , François Bénard , Jonn Wu , Roberto Fedrigo , Haley Clark

The ability to automatically detect certain types of cells or cellular subunits in microscopy images is of significant interest to a wide range of biomedical research and clinical practices. Cell detection methods have evolved from…

Computer Vision and Pattern Recognition · Computer Science 2018-02-22 Yao Xue , Nilanjan Ray
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