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We introduce the EMC algorithm for reconstructing a particle's 3D diffraction intensity from very many photon shot-noise limited 2D measurements, when the particle orientation in each measurement is unknown. The algorithm combines a…

Data Analysis, Statistics and Probability · Physics 2010-03-04 Duane Ne-Te Loh , Veit Elser

Sparsity is one of the key concepts that allows the recovery of signals that are subsampled at a rate significantly lower than required by the Nyquist-Shannon sampling theorem. Our proposed framework uses arbitrary multiscale transforms,…

Optimization and Control · Mathematics 2017-05-31 Jackie Ma , Maximilian März

Analytical electron microscopy and spectroscopy of biological specimens, polymers, and other beam sensitive materials has been a challenging area due to irradiation damage. There is a pressing need to develop novel imaging and spectroscopic…

Machine Learning · Computer Science 2017-07-14 Yan Zhang , G. M. Dilshan Godaliyadda , Nicola Ferrier , Emine B. Gulsoy , Charles A. Bouman , Charudatta Phatak

Data scarcity is a fundamental barrier in Electrical Impedance Tomography (EIT), as undersampled Dirichlet-to-Neumann (DtN) measurements can substantially degrade conductivity reconstructions. We address this bottleneck by completing…

Numerical Analysis · Mathematics 2026-02-10 Ke Chen , Haizhao Yang , Chugang Yi

Compressed sensing is an image reconstruction technique to achieve high-quality results from limited amount of data. In order to achieve this, it utilizes prior knowledge about the samples that shall be reconstructed. Focusing on image…

State-of-the-art electron microscopes such as scanning electron microscopes (SEM), scanning transmission electron microscopes (STEM) and transmission electron microscopes (TEM) have become increasingly sophisticated. However, the quality of…

Computational Physics · Physics 2023-03-31 I. Lobato , T. Friedrich , S. Van Aert

When working with quantum states, analysis of the final quantum state generated through probabilistic measurements is essential. This analysis is typically conducted by constructing the density matrix from either partial or full tomography…

Quantum Physics · Physics 2025-01-14 Rohit Prasad , Pratyay Ghosh , Ronny Thomale , Tobias Huber-Loyola

Schemes for X-ray imaging single protein molecules using new x-ray sources, like x-ray free electron lasers (XFELs), require processing many frames of data that are obtained by taking temporally short snapshots of identical molecules, each…

Data Analysis, Statistics and Probability · Physics 2015-06-17 Kartik Ayyer , Hugh T. Philipp , Mark W. Tate , Veit Elser , Sol M. Gruner

Three-dimensional reconstruction of atomic structure, known as atomic electron tomography (AET), has found increasing applications in materials science. The AET has been limited to very small nanoparticles due to the challenges of obtaining…

Materials Science · Physics 2024-01-24 Liangze Mao , Jizhe Cui , Rong Yu

The need for tomographic reconstruction from sparse measurements arises when the measurement process is potentially harmful, needs to be rapid, or is uneconomical. In such cases, information from previous longitudinal scans of the same…

Image and Video Processing · Electrical Eng. & Systems 2019-09-13 Preeti Gopal , Sharat Chandran , Imants Svalbe , Ajit Rajwade

Direct observation of nanoscale transformations in three dimensions (3D) is essential for understanding materials evolution under operating conditions, yet dynamic electron tomography remains limited by slow tilt series acquisition and by…

Ultra low radiation dose in X-ray Computed Tomography (CT) is an important clinical objective in order to minimize the risk of carcinogenesis. Compressed Sensing (CS) enables significant reductions in radiation dose to be achieved by…

A single-particle cryo-electron microscopy (cryo-EM) measurement, called a micrograph, consists of multiple two-dimensional tomographic projections of a three-dimensional (3-D) molecular structure at unknown locations, taken under unknown…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Shay Kreymer , Amit Singer , Tamir Bendory

Many imaging technologies rely on tomographic reconstruction, which requires solving a multidimensional inverse problem given a finite number of projections. Backprojection is a popular class of algorithm for tomographic reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-03 Xueqing Liu , Paul Sajda

We review developments, issues and challenges in Electrical Impedance Tomography (EIT), for the 4th Workshop on Biomedical Applications of EIT, Manchester 2003. We focus on the necessity for three dimensional data collection and…

Medical Physics · Physics 2008-07-31 William R. B. Lionheart

Low-dose emission tomography (ET) plays a crucial role in medical imaging, enabling the acquisition of functional information for various biological processes while minimizing the patient dose. However, the inherent randomness in the photon…

In electrical impedance tomography, algorithms based on minimizing a linearized residual functional have been widely used due to their flexibility and good performance in practice. However, no rigorous convergence results have been…

Analysis of PDEs · Mathematics 2018-10-11 Bastian Harrach , Mach Nguyet Minh

Variational formulations of reconstruction in computed tomography have the notable drawback of requiring repeated evaluations of both the forward Radon transform and either its adjoint or an approximate inverse transform which are…

Numerical Analysis · Mathematics 2017-05-23 Richard C. Barnard , Rick Archibald

This paper concerns electromagnetic 3D subsurface imaging in connection with sparsity of signal sources. We explored an imaging approach that can be implemented in situations that allow obtaining a large amount of data over a surface or a…

Instrumentation and Methods for Astrophysics · Physics 2016-08-26 Sampsa Pursiainen , Mikko Kaasalainen

Objective: Absolute images have important applications in medical Electrical Impedance Tomography (EIT) imaging, but the traditional minimization and statistical based computations are very sensitive to modeling errors and noise. In this…

Analysis of PDEs · Mathematics 2018-08-16 S. J. Hamilton , J. L. Mueller , T. R. Santos