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We study critical random Boolean networks with two inputs per node that contain only canalyzing functions. We present a phenomenological theory that explains how a frozen core of nodes that are frozen on all attractors arises. This theory…

Statistical Mechanics · Physics 2009-11-11 U. Paul , V. Kaufman , B. Drossel

Estimating the influence that individual nodes have on one another in a Boolean network is essential to predict and control the system's dynamical behavior, for example, detecting key therapeutic targets to control pathways in models of…

Physics and Society · Physics 2023-11-02 Thomas Parmer , Filippo Radicchi

A beta-skeleton is a planar proximity undirected graph of an Euclidean point set where nodes are connected by an edge if their lune-based neighborhood contains no other points of the given set. Parameter $\beta$ determines size and shape of…

Cellular Automata and Lattice Gases · Physics 2010-11-23 Andrew Adamatzky

Random Boolean networks, originally invented as models of genetic regulatory networks, are simple models for a broad class of complex systems that show rich dynamical structures. From a biological perspective, the most interesting networks…

Disordered Systems and Neural Networks · Physics 2009-11-07 Joshua E. S. Socolar , Stuart A. Kauffman

We study an evolutionary version of the spatial prisoner's dilemma game, where the agents are placed in a random graph. For lattices with fixed connectivity, $\alpha$, we show that for low values of $\alpha$ the final density of cooperating…

Statistical Mechanics · Physics 2007-05-23 O. Durán , R. Mulet

We introduce a model based on the one-dimensional nonlinear Schroedinger equation (NLSE) with the critical (quintic) or supercritical self-focusing nonlinearity. We demonstrate that a family of solitons, which are unstable in this setting…

Pattern Formation and Solitons · Physics 2019-05-22 Li Wang , Boris A. Malomed , Zhenya Yan

We study synchronization for linearly coupled temporal networks of heterogeneous time-dependent nonlinear agents via the convergence of attracting trajectories of each node. The results are obtained by constructing and studying the…

Dynamical Systems · Mathematics 2024-10-23 Hildeberto Jardón-Kojakhmetov , Christian Kuehn , Iacopo P. Longo

The study of control mechanisms of biological systems allows for interesting applications in bioengineering and medicine, for instance in cell reprogramming or drug target identification. A control strategy often consists of a set of…

Molecular Networks · Quantitative Biology 2022-03-28 Laura Cifuentes-Fontanals , Elisa Tonello , Heike Siebert

Boolean networks are discrete dynamical systems for modeling regulation and signaling in living cells. We investigate a particular class of Boolean functions with inhibiting inputs exerting a veto (forced zero) on the output. We give…

Molecular Networks · Quantitative Biology 2014-09-05 Haleh Ebadi , Konstantin Klemm

The complex interactions involved in regulation of a cell's function are captured by its interaction graph. More often than not, detailed knowledge about enhancing or suppressive regulatory influences and cooperative effects is lacking and…

Molecular Networks · Quantitative Biology 2013-02-15 Gunnar Boldhaus , Florian Greil , Konstantin Klemm

A method is presented to analyze the stability of feedback systems with neural network controllers. Two stability theorems are given to prove asymptotic stability and to compute an ellipsoidal inner-approximation to the region of attraction…

Systems and Control · Electrical Eng. & Systems 2021-01-28 He Yin , Peter Seiler , Murat Arcak

A Boolean network (BN) is a discrete dynamical system defined by a Boolean function that maps to the domain itself. A trap space of a BN is a generalization of a fixed point, which is defined as the sub-hypercubes closed by the function of…

Discrete Mathematics · Computer Science 2024-10-21 Kyungduk Moon , Kangbok Lee , Loïc Paulevé

We initiate a line of investigation into biological neural networks from an algorithmic perspective. We develop a simplified but biologically plausible model for distributed computation in stochastic spiking neural networks and study…

Neural and Evolutionary Computing · Computer Science 2016-10-10 Nancy Lynch , Cameron Musco , Merav Parter

The main purpose of this work is the mathematical modelling of large populations of cells under different deterministic interactions among themselves, in balance with naturally random diffusion. We focus on cell-cell adhesion mechanisms for…

Analysis of PDEs · Mathematics 2025-03-19 Carlo Giambiagi Ferrari , Francisco Guillen-Gonzalez , Mayte Perez-Llanos , Antonio Suarez

New results on the behaviour of the fast motion in slow-fast systems of ODEs with dependence on the fast time are given in terms of tracking of nonautonomous attractors. Under quite general assumptions, including the uniform ultimate…

Dynamical Systems · Mathematics 2024-06-24 Iacopo P. Longo , Rafael Obaya , Ana M. Sanz

Recent empirical studies have identified fixed point iteration phenomena in deep neural networks, where the hidden state tends to stabilize after several layers, showing minimal change in subsequent layers. This observation has spurred the…

Machine Learning · Computer Science 2024-10-16 Yekun Ke , Xiaoyu Li , Yingyu Liang , Zhenmei Shi , Zhao Song

Biological systems operate under persistent noise, which can alter system states and induce transitions between attractors. Here, we study the attractor dynamics of Boolean networks focusing on the transitions between attractors induced by…

Molecular Networks · Quantitative Biology 2026-03-05 Byungjoon Min , Jeehye Choi , Reinhard Laubenbacher

We investigate the propagation of perturbations in Boolean networks by evaluating the Derrida plot and modifications of it. We show that even small Random Boolean Networks agree well with the predictions of the annealed approximation, but…

Statistical Mechanics · Physics 2009-05-06 Christoph Fretter , Agnes Szejka , Barbara Drossel

Interactions between neighboring cells are essential for generating or refining patterns in a number of biological systems. We propose a discrete filtering approach to predict how networks of cells modulate spatially varying input signals…

Tissues and Organs · Quantitative Biology 2019-02-14 Melinda Liu Perkins , Murat Arcak

Combinatorial threshold-linear networks (CTLNs) are a special class of recurrent neural networks whose dynamics are tightly controlled by an underlying directed graph. Recurrent networks have long been used as models for associative memory…

Neurons and Cognition · Quantitative Biology 2023-11-21 Carina Curto , Jesse Geneson , Katherine Morrison