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Computing stands to be radically improved by neuromorphic computing (NMC) approaches inspired by the brain's incredible efficiency and capabilities. Most NMC research, which aims to replicate the brain's computational structure and…

Neural and Evolutionary Computing · Computer Science 2022-03-02 J. Darby Smith , Aaron J. Hill , Leah E. Reeder , Brian C. Franke , Richard B. Lehoucq , Ojas Parekh , William Severa , James B. Aimone

Scaling neural network models has delivered dramatic quality gains across ML problems. However, this scaling has increased the reliance on efficient distributed training techniques. Accordingly, as with other distributed computing…

Hardware Architecture · Computer Science 2023-05-04 Suchita Pati , Shaizeen Aga , Mahzabeen Islam , Nuwan Jayasena , Matthew D. Sinclair

The deployment of ML models on edge devices is challenged by limited computational resources and energy availability. While split computing enables the decomposition of large neural networks (NNs) and allows partial computation on both edge…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-11-01 Daniel May , Alessandro Tundo , Shashikant Ilager , Ivona Brandic

Metabolomics is becoming a mature part of analytical chemistry as evidenced by the growing number of publications and attendees of international conferences dedicated to this topic. Yet, a systematic treatment of the fundamental structure…

Quantitative Methods · Quantitative Biology 2019-06-19 Age K. Smilde , Thomas Hankemeier

Scientific workflows are widely used to automate scientific data analysis and often involve processing large quantities of data on compute clusters. As such, their execution tends to be long-running and resource intensive, leading to…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-20 Kathleen West , Fabian Lehmann , Vasilis Bountris , Ulf Leser , Yehia Elkhatib , Lauritz Thamsen

Molecular dynamics (MD) simulations have transformed our understanding of the nanoscale, driving breakthroughs in materials science, computational chemistry, and several other fields, including biophysics and drug design. Even on exascale…

As the popularity of quantum computing continues to grow, efficient quantum machine access over the cloud is critical to both academic and industry researchers across the globe. And as cloud quantum computing demands increase exponentially,…

Quantum Physics · Physics 2022-03-28 Gokul Subramanian Ravi , Kaitlin N. Smith , Prakash Murali , Frederic T. Chong

In this paper we describe the development of a streamlined framework for large-scale ATLAS pMSSM reinterpretations of LHC Run-2 analyses using containerised computational workflows. The project is looking to assess the global coverage of…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-07 Marco Donadoni , Matthew Feickert , Lukas Heinrich , Yang Liu , Audrius Mečionis , Vladyslav Moisieienkov , Tibor Šimko , Giordon Stark , Marco Vidal García

Energy consumption of Cloud data centers has been a major concern of many researchers, and one of the reasons for huge energy consumption of Clouds lies in the inefficient utilization of computing resources. Besides energy consumption,…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-03-26 Minxian Xu , Adel Nadjaran Toosi , Rajkumar Buyya

The metabolic wiring of patient cells is altered drastically in many diseases, including cancer. Understanding the nature of such changes may pave the way for new therapeutic opportunities, as well as the development of personalized…

Molecular Networks · Quantitative Biology 2020-02-12 Ali Cakmak , M. Hasan Celik

We profile the impact of computation and inter-processor communication on the energy consumption and on the scaling of cortical simulations approaching the real-time regime on distributed computing platforms. Also, the speed and energy…

Applications with irregular data structures, data-dependent control flows and fine-grained data transfers (e.g., real-world graph computations) perform poorly on cache-based systems. We propose the UpDown accelerator that supports…

Computer simulations have become a very powerful tool for scientific research. In order to facilitate research in computational biology, the BioDynaMo project aims at a general platform for biological computer simulations, which should be…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-08-18 Lukas Breitwieser , Roman Bauer , Alberto Di Meglio , Leonard Johard , Marcus Kaiser , Marco Manca , Manuel Mazzara , Fons Rademakers , Max Talanov

The cost of moving data between the memory units and the compute units is a major contributor to the execution time and energy consumption of modern workloads in computing systems. At the same time, we are witnessing an enormous amount of…

Hardware Architecture · Computer Science 2022-08-19 Gagandeep Singh

With the rapid advancement of Big Data platforms such as Hadoop, Spark, and Dataflow, many tools are being developed that are intended to provide end users with an interactive environment for large-scale data analysis (e.g., IQmulus).…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-25 Amit Kumar Mondal , Banani Roy , Chanchal K. Roy , Kevin A. Schneider

Every year the PHENIX collaboration deals with increasing volume of data (now about 1/4 PB/year). Apparently the more data the more questions how to process all the data in most efficient way. In recent past many developments in HEP…

Distributed, Parallel, and Cluster Computing · Computer Science 2007-05-23 Barbara Jacak , Roy Lacey , Dave Morrison , Irina Sourikova , Andrey Shevel , Qiu Zhiping

As artificial intelligence (AI) and machine learning (ML) technologies disrupt a wide range of industries, cloud datacenters face ever-increasing demand in inference workloads. However, conventional CPU-based servers cannot handle excessive…

Hardware Architecture · Computer Science 2022-06-08 Jung-Hoon Kim , Sungyeob Yoo , Seungjae Moon , Joo-Young Kim

We assess costs and efficiency of state-of-the-art high performance cloud computing compared to a traditional on-premises compute cluster. Our use case are atomistic simulations carried out with the GROMACS molecular dynamics (MD) toolkit…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-16 Carsten Kutzner , Christian Kniep , Austin Cherian , Ludvig Nordstrom , Helmut Grubmüller , Bert L. de Groot , Vytautas Gapsys

Hyperscalars run services across a large fleet of servers, serving billions of users worldwide. These services, however, behave differently than commonly available benchmark suites, resulting in server architectures that are not optimized…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-05-03 Suyash Mahar , Hao Wang , Wei Shu , Abhishek Dhanotia

Network traffic is difficult to monitor and analyze, especially in high-bandwidth networks. Performance analysis, in particular, presents extreme complexity and scalability challenges. GPU (Graphics Processing Unit) technology has been…

Networking and Internet Architecture · Computer Science 2011-08-09 Wenji Wu , Phil DeMar , Don Holmgren , Amitoj Singh , Ruth Pordes