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Brillouin and Raman scattering spectroscopy are established techniques for the nondestructive contactless and label-free readout of mechanical, chemical and structural properties of condensed matter. Brillouin-Raman investigations currently…

Convolutional neural networks (CNNs) are widely used for image recognition and text analysis, and have been suggested for application on one-dimensional data as a way to reduce the need for pre-processing steps. Pre-processing is an…

Machine Learning · Computer Science 2020-05-18 Ine L. Jernelv , Dag Roar Hjelme , Yuji Matsuura , Astrid Aksnes

Confocal Raman microscopy offers a particular pathway for monitoring chemical "fingerprints" of intracellular components like the cell membrane, organelles, and nucleus. Nevertheless, conventional Raman acquisitions of fixed or randomly…

Phase estimation protocols provide a fundamental benchmark for the field of quantum metrology. The latter represents one of the most relevant applications of quantum theory, potentially enabling the capability of measuring unknown physical…

Mass spectrometry is a widely used method to study molecules and processes in medicine, life sciences, chemistry, catalysis, and industrial product quality control, among many other applications. One of the main features of some mass…

Chemical Physics · Physics 2024-07-02 Daniil A. Boiko , Valentine P. Ananikov

Spectral variability significantly impacts the accuracy and convergence of hyperspectral unmixing algorithms. Many methods address complex spectral variability; yet large-scale distortions to the scale of the observed pixel signatures due…

Image and Video Processing · Electrical Eng. & Systems 2026-05-18 Praveen Sumanasekara , Athulya Ratnayake , Buddhi Wijenayake , Keshawa Ratnayake , Roshan Godaliyadda , Parakrama Ekanayake , Vijitha Herath

Detecting stress in plants is crucial for both open-farm and controlled-environment agriculture. Biomolecules within plants serve as key stress indicators, offering vital markers for continuous health monitoring and early disease detection.…

Deep learning classifiers for Raman spectroscopy are increasingly reported to outperform classical chemometric approaches. However their evaluations are often conducted in isolation or compared against traditional machine learning methods…

Machine Learning · Computer Science 2026-01-23 Adithya Sineesh , Akshita Kamsali

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield

Photoacoustic Microscopy (PAM) images integrating the advantages of optical contrast and acoustic resolution have been widely used in brain studies. However, there exists a trade-off between scanning speed and image resolution. Compared…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Kai Pan , Linyang Li , Li Lin , Pujin Cheng , Junyan Lyu , Lei Xi , Xiaoyin Tang

Nonlinear optical processes are used in biological microscopy to surpass the diffraction limit on resolution, image deeper into brain tissues, and identify biomolecules without exogenous labels. These techniques typically require high…

Interpretability is crucial to enhance trust in machine learning models for medical diagnostics. However, most state-of-the-art image classifiers based on neural networks are not interpretable. As a result, clinicians often resort to known…

Brillouin imaging relies on the reliable extraction of subtle spectral information from hyperspectral datasets. To date, the mainstream practice has been using line fitting of spectral features to retrieve the average peak shift and…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 YuChen Xiang , Kai Ling C. Seow , Carl Paterson , Peter Török

Many problems within personalized medicine and digital health rely on the analysis of continuous-time functional biomarkers and other complex data structures emerging from high-resolution patient monitoring. In this context, this work…

Machine Learning · Statistics 2025-01-14 Marcos Matabuena

Machine learning tasks involving biomedical signals frequently grapple with issues such as limited data availability, imbalanced datasets, labeling complexities, and the interference of measurement noise. These challenges often hinder the…

Signal Processing · Electrical Eng. & Systems 2024-01-30 Xiaomin Li , Mykhailo Sakevych , Gentry Atkinson , Vangelis Metsis

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

State estimation or filtering serves as a fundamental task to enable intelligent decision-making in applications such as autonomous vehicles, robotics, healthcare monitoring, smart grids, intelligent transportation, and predictive…

Machine Learning · Computer Science 2025-06-16 Aamir Hussain Chughtai

Most machine learning techniques are based upon statistical learning theory, often simplified for the sake of computing speed. This paper is focused on the uncertainty aspect of mathematical modeling in machine learning. Regression analysis…

Machine Learning · Computer Science 2022-06-07 Valentin Arkov

Purpose: Machine learning is broadly used for clinical data analysis. Before training a model, a machine learning algorithm must be selected. Also, the values of one or more model parameters termed hyper-parameters must be set. Selecting…

Machine Learning · Computer Science 2018-12-10 Xueqiang Zeng , Gang Luo

Quantitative Magnetic Resonance Imaging (qMRI) provides researchers insight into pathological and physiological alterations of living tissue, with the help of which researchers hope to predict (local) therapeutic efficacy early and…

Applications · Statistics 2008-07-30 Xiaoxi Zhang , Timothy D. Johnson , Roderick J. A. Little , Yue Cao