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There is strong interest in estimating how the magnitude of treatment effects of an intervention vary across sub-groups of the population of interest. In our paper, we propose a two-study approach to first propose and then test…

Methodology · Statistics 2020-06-23 Rahul Ladhania , Amelia Haviland , Neeraj Sood , Edward Kennedy , Ateev Mehrotra

In this paper, we propose algorithms that leverage a known community structure to make group testing more efficient. We consider a population organized in disjoint communities: each individual participates in a community, and its infection…

Information Theory · Computer Science 2021-03-18 Pavlos Nikolopoulos , Tao Guo , Sundara Rajan Srinivasavaradhan , Christina Fragouli , Suhas Diggavi

In general, recommender systems are designed to provide personalized items to a user. But in few cases, items are recommended for a group, and the challenge is to aggregate the individual user preferences to infer the recommendation to a…

Information Retrieval · Computer Science 2021-07-16 Chintoo Kumar , C. Ravindranath Chowdary

Due to the complexity of the human body, most diseases present a high inter-personal variability in the way they manifest, i.e. in their phenotype, which has important clinical repercussions - as for instance the difficulty in defining…

Physics and Society · Physics 2018-06-06 Massimiliano Zanin , Juan Manuel Tuñas , Ernestina Menasalvas

Machine learning approaches have been effective in predicting adverse outcomes in different clinical settings. These models are often developed and evaluated on datasets with heterogeneous patient populations. However, good predictive…

Machine Learning · Computer Science 2018-06-11 Harini Suresh , Jen J. Gong , John Guttag

Recent years have seen an increased focus into the tasks of predicting hospital inpatient risk of deterioration and trajectory evolution due to the availability of electronic patient data. A common approach to these problems involves…

Machine Learning · Computer Science 2020-11-18 Henrique Aguiar , Mauro Santos , Peter Watkinson , Tingting Zhu

Group testing enables to identify infected individuals in a population using a smaller number of tests than individual testing. To achieve this, group testing algorithms commonly assume knowledge of the number of infected individuals;…

Information Theory · Computer Science 2023-05-16 Chaorui Yao , Pavlos Nikolopoulos , Christina Fragouli

This paper considers making active learning more sensible from a medical perspective. In practice, a disease manifests itself in different forms across patient cohorts. Existing frameworks have primarily used mathematical constructs to…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Yash-yee Logan , Ryan Benkert , Ahmad Mustafa , Gukyeong Kwon , Ghassan AlRegib

In identifying infected patients in a population, group testing is an effective method to reduce the number of tests and correct the test errors. In the group testing procedure, tests are performed on pools of specimens collected from…

Machine Learning · Statistics 2021-02-10 Ayaka Sakata

Healthcare providers face significant challenges with monitoring and managing patient data outside of clinics, particularly with insufficient resources and limited feedback on their patients' conditions. Effective management of these…

Databases · Computer Science 2023-11-14 Daniel Bloor , Nnamdi Ugwuoke , David Taylor , Keir Lewis , Luis Mur , Chuan Lu

Identifying subgroups, which respond differently to a treatment, both in terms of efficacy and safety, is an important part of drug development. A well-known challenge in exploratory subgroup analyses is the small sample size in the…

Computation · Statistics 2016-06-28 Marius Thomas , Björn Bornkamp

Identifying a patient's key problems over time is a common task for providers at the point care, yet a complex and time-consuming activity given current electric health records. To enable a problem-oriented summarizer to identify a…

Applications · Statistics 2020-03-26 Gal Levy-Fix , Jason Zucker , Konstantin Stojanovic , Noémie Elhadad

Social network analysis is pivotal for organizations aiming to leverage the vast amounts of data generated from user interactions on social media and other digital platforms. These interactions often reveal complex social structures, such…

Social and Information Networks · Computer Science 2025-02-12 Maxence Morin , Baptiste Hemery , Fabrice Jeanne , Estelle Pawlowski-Cherrier

The use of unsupervised learning to identify patient subgroups has emerged as a potentially promising direction to improve the efficiency of Intensive Care Units (ICUs). By identifying subgroups of patients with similar levels of medical…

Machine Learning · Computer Science 2024-03-06 Harry Mayne , Guy Parsons , Adam Mahdi

Many massive data are assembled through collections of information of a large number of individuals in a population. The analysis of such data, especially in the aspect of individualized inferences and solutions, has the potential to create…

Methodology · Statistics 2019-09-18 Chencheng Cai , Rong Chen , Min-ge Xie

Group testing has recently attracted significant attention from the research community due to its applications in diagnostic virology. An instance of the group testing problem includes a ground set of individuals which includes a small…

Information Theory · Computer Science 2022-02-25 Esmaeil Karimi , Anoosheh Heidarzadeh , Krishna R. Narayanan , Alex Sprintson

The dearth of prescribing guidelines for physicians is one key driver of the current opioid epidemic in the United States. In this work, we analyze medical and pharmaceutical claims data to draw insights on characteristics of patients who…

Machine Learning · Computer Science 2020-05-01 Chirag Nagpal , Dennis Wei , Bhanukiran Vinzamuri , Monica Shekhar , Sara E. Berger , Subhro Das , Kush R. Varshney

Patient similarity analysis is important in health care applications. It takes patient information such as their electronic medical records and genetic data as input and computes the pairwise similarity between patients. Procedures of…

Machine Learning · Computer Science 2020-12-04 Leyu Dai , He Zhu , Dianbo Liu

This paper presents a method for building patient-based networks that we call Precision disease networks, and its uses for predicting medical outcomes. Our methodology consists of building networks, one for each patient or case, that…

Quantitative Methods · Quantitative Biology 2019-11-01 J. Cabrera , D. Amaratunga , W. Kostis , J Kostis

Peer-grouping is used in many sectors for organisational learning, policy implementation, and benchmarking. Clustering provides a statistical, data-driven method for constructing meaningful peer groups, but peer groups must be compatible…

Applications · Statistics 2021-07-14 Daniel William Kennedy , Jessica Cameron , Paul Pao-Yen Wu , Kerrie Mengersen