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Bayesian global optimization (BGO) is an efficient surrogate-assisted technique for problems involving expensive evaluations. A parallel technique can be used to parallelly evaluate the true-expensive objective functions in one iteration to…

Artificial Intelligence · Computer Science 2022-08-09 Kaifeng Yang , Guozhi Dong , Michael Affenzeller

Graph Neural Network (GNN) has achieved state-of-the-art performance in various high-stake prediction tasks, but multiple layers of aggregations on graphs with irregular structures make GNN a less interpretable model. Prior methods use…

Machine Learning · Computer Science 2021-11-30 Yifei Liu , Chao Chen , Yazheng Liu , Xi Zhang , Sihong Xie

Purpose: Current inverse planning methods for IMRT are limited because they are not designed to explore the trade-offs between the competing objectives between the tumor and normal tissues. Our goal was to develop an efficient…

Medical Physics · Physics 2015-06-04 Clay Holdsworth , Minsun Kim , Jay Liao , Mark H Phillips

Particle Swarm Optimization (PSO) and Ant Colony Optimization (ACO) are simple, easy to implement, their robustness to control parameters, and their computational efficiency when compared with mathematical algorithms and other heuristic…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-03-24 Harsha R. Gaikwad , Pradnyarani K. Mahind , Sandeep U. Mane

Monte Carlo simulation is the most accurate method for absorbed dose calculations in radiotherapy. Its efficiency still requires improvement for routine clinical applications, especially for online adaptive radiotherapy. In this paper, we…

Medical Physics · Physics 2015-05-14 Xun Jia , Xuejun Gu , Josep Sempau , Dongju Choi , Amitava Majumdar , Steve B. Jiang

This manuscript addresses the challenge of designing functionally graded materials (FGMs) for arbitrary-shaped domains. Towards this goal, the present work proposes a generic volume fraction profile generation algorithm based on Gaussian…

Machine Learning · Computer Science 2025-11-18 Chaitanya Kumar Konda , Piyush Agrawal , Shivansh Srivastava , Manish Agrawal

Various medical and surgical units operate in a typical hospital and to treat their patients these units compete for infrastructure like operating rooms (OR) and ward beds. How that competition is regulated affects the capacity and output…

Artificial Intelligence · Computer Science 2023-08-16 Robert L Burdett , Paul Corry , Prasad Yarlagadda , David Cook , Sean Birgan

A major bottleneck in scenario-based Sample Average Approximation (SAA) for stochastic programming (SP) is the cost of solving an exact second-stage problem for every scenario, especially when each scenario contains an NP-hard combinatorial…

Optimization and Control · Mathematics 2026-05-12 Jingyi Zhao , Linxin Yang , Haohua Zhang , Qile He , Tian Ding

Autonomous large-scale machine operations require fast, efficient, and collision-free motion planning while addressing unique challenges such as hydraulic actuation limits and underactuated joint dynamics. This paper presents a novel…

Robotics · Computer Science 2025-03-19 Minh Nhat Vu , Gerald Ebmer , Alexander Watcher , Marc-Philip Ecker , Giang Nguyen , Tobias Glueck

Many emerging cyber-physical systems, such as autonomous vehicles and robots, rely heavily on artificial intelligence and machine learning algorithms to perform important system operations. Since these highly parallel applications are…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-02-07 An Zou , Jing Li , Christopher D. Gill , Xuan Zhang

Purpose: To develop a multi-criteria optimization framework for image guided radiotherapy. Methods: An algorithm is proposed for a multi-criteria framework for the purpose of patient setup verification decision processes. Optimal patient…

Medical Physics · Physics 2011-08-16 Brian Winey , James Balter

Purpose: We sought to evaluate the feasibility of using machine learning algorithms for multipoint plastic scintillator detector calibration in high-dose-rate brachytherapy. Methods: The dosimetry system consisted of an optimized 1-mm-core…

Treatment planning system calculations in inhomogeneous regions may present significant inaccuracies due to loss of electronic equilibrium. In this study, three different dose calculation algorithms, pencil beam, collapsed cone, and…

Medical Physics · Physics 2015-03-12 Sung Jin Kim , Dong Ho Kim , Sung Kyu Kim

Optimizing GPU kernels manually is a challenging and time-consuming task. With the rapid development of LLMs, automated GPU kernel optimization is gradually becoming a tangible reality. However, current LLM-driven automated optimization…

Machine Learning · Computer Science 2026-03-10 Yuxuan Han , Meng-Hao Guo , Zhengning Liu , Wenguang Chen , Shi-Min Hu

Treatment planning in radiotherapy is inherently a multi-criteria optimization (MCO) problem. Traditionally, the treatment's robustness is not formulated as a part of this decision making problem, but dealt with separately through margins…

Medical Physics · Physics 2026-03-27 Remo Cristoforetti , Philipp Süss , Tobias Becher , Niklas Wahl

With large-scale Integral Field Spectroscopy (IFS) surveys of thousands of galaxies currently under-way or planned, the astronomical community is in need of methods, techniques and tools that will allow the analysis of huge amounts of data.…

Instrumentation and Methods for Astrophysics · Physics 2015-12-22 Georgios Bekiaris , Karl Glazebrook , Christopher J. Fluke , Roberto Abraham

Large scale graph optimization problems arise in many fields. This paper presents an extensible, high performance framework (named OpenGraphGym-MG) that uses deep reinforcement learning and graph embedding to solve large graph optimization…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-06-25 Weijian Zheng , Dali Wang , Fengguang Song

Similarity search, the task of identifying objects most similar to a given query object under a specific metric, has gathered significant attention due to its practical applications. However, the absence of coordinate information to…

Databases · Computer Science 2024-05-14 Yifan Zhu , Ruiyao Ma , Baihua Zheng , Xiangyu Ke , Lu Chen , Yunjun Gao

Proton pencil beam scanning (PBS) treatment planning for head & neck (H&N) cancers involves numerous conflicting objectives, requiring iterative objective parameter adjustments to balance multiple clinical goals. We propose a…

Artificial Intelligence · Computer Science 2025-09-16 Qingqing Wang , Liqiang Xiao , Chang Chang

Cardiac resynchronization therapy (CRT) is a common intervention for patients with dyssynchronous heart failure, yet approximately one-third of recipients fail to respond, partly due to suboptimal lead placement. Identifying optimal pacing…

Computational Engineering, Finance, and Science · Computer Science 2026-02-13 Ehsan Naghavi , Haifeng Wang , Vahid Ziaei Rad , Julius Guccione , Ghassan Kassab , Vishnu Boddeti , Seungik Baek , Lik-Chuan Lee