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Functional brain connectivity, as revealed through distant correlations in the signals measured by functional Magnetic Resonance Imaging (fMRI), is a promising source of biomarkers of brain pathologies. However, establishing and using…

Series and polynomial regression are able to approximate the same function classes as neural networks. However, these methods are rarely used in practice, although they offer more interpretability than neural networks. In this paper, we…

Machine Learning · Statistics 2024-09-19 Sylvia Klosin , Jaume Vives-i-Bastida

Biological network alignment (NA) aims to identify similar regions between molecular networks of different species. NA can be local or global. Just as the recent trend in the NA field, we also focus on global NA, which can be pairwise (PNA)…

Molecular Networks · Quantitative Biology 2020-04-28 Vipin Vijayan , Shawn Gu , Eric Krebs , Lei Meng , Tijana Milenkovic

Weight sharing is a popular approach to reduce the cost of neural architecture search (NAS) by reusing the weights of shared operators from previously trained child models. However, the rank correlation between the estimated accuracy and…

Computation and Language · Computer Science 2022-07-25 Jin Xu , Xu Tan , Kaitao Song , Renqian Luo , Yichong Leng , Tao Qin , Tie-Yan Liu , Jian Li

Discovery of microRNAs (miRNAs) relies on predictive models for characteristic features from miRNA precursors (pre-miRNAs). The short length of miRNA genes and the lack of pronounced sequence features complicate this task. To accommodate…

In many applications of shape analysis, lengths between some landmarks are constrained. For instance, biomolecules often have some bond lengths and some bond angles constrained, and variation occurs only along unconstrained bonds and…

Methodology · Statistics 2025-02-25 Kanti V. Mardia , Benjamin Eltzner , Stephan F. Huckemann

The advancement of biomedical named entity recognition (BNER) and biomedical relation extraction (BRE) researches promotes the development of text mining in biological domains. As a cornerstone of BRE, robust BNER system is required to…

Information Retrieval · Computer Science 2020-08-20 Ming-Siang Huang , Po-Ting Lai , Richard Tzong-Han Tsai , Wen-Lian Hsu

In the field of systems biology, differential equations are commonly used to model biological systems, but solving them for large-scale and complex systems can be computationally expensive. Recently, the integration of machine learning and…

Machine Learning · Computer Science 2025-02-12 Enze Xu , Minghan Chen

Binary neural networks utilize 1-bit quantized weights and activations to reduce both the model's storage demands and computational burden. However, advanced binary architectures still incorporate millions of inefficient and…

Machine Learning · Computer Science 2024-03-07 Ruichen Ma , Guanchao Qiao , Yian Liu , Liwei Meng , Ning Ning , Yang Liu , Shaogang Hu

Existing face recognition using deep neural networks is difficult to know what kind of features are used to discriminate the identities of face images clearly. To investigate the effective features for face recognition, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2018-08-16 Bong-Nam Kang , Yonghyun Kim , Daijin Kim

Binarized Neural Networks (BNNs) have recently attracted significant interest due to their computational efficiency. Concurrently, it has been shown that neural networks may be overly sensitive to "attacks" - tiny adversarial changes in the…

Machine Learning · Computer Science 2018-10-09 Elias B. Khalil , Amrita Gupta , Bistra Dilkina

Scientific foundation models hold great promise for advancing nuclear and particle physics by improving analysis precision and accelerating discovery. Yet, progress in this field is often limited by the lack of openly available large scale…

Data Analysis, Statistics and Probability · Physics 2025-09-09 Shuhang Li , Yi Huang , David Park , Xihaier Luo , Haiwang Yu , Yeonju Go , Christopher Pinkenburg , Yuewei Lin , Shinjae Yoo , Joseph Osborn , Christof Roland , Jin Huang , Yihui Ren

The great success of neural networks in recognizing hidden patterns and correlations in complex data lies in the way they take advantage of the large number of parameters and nonlinear single-unit activation, jointly. Restricted Boltzmann…

Disordered Systems and Neural Networks · Physics 2026-05-20 Giovanni di Sarra , Yasser Roudi

Recent advances in microelectronics have enabled the realization of Wireless Body Area Networks (WBANs). Increasing the transmission power of WBAN's nodes improves the Signal to Interference plus Noise Ratio (SINR), and hence decreases the…

Networking and Internet Architecture · Computer Science 2017-01-31 Mohamad Jaafar Ali , Hassine Moungla , Ahmed Mehaoua

Understanding the molecular determinants of specificity in protein-protein interaction is an outstanding challenge of postgenome biology. The availability of large protein databases generated from sequences of hundreds of bacterial genomes…

Biomolecules · Quantitative Biology 2009-01-12 M. Weigt , R. A. White , H. Szurmant , J. A. Hoch , T. Hwa

RNA structure prediction is a challenging problem, especially with pseudoknots. Recently, there has been a shift from the classical minimum free energy-based methods (MFE) to partition function-based ones that assemble structures using…

Biomolecules · Quantitative Biology 2020-01-10 Liang Zhang , He Zhang , David H. Mathews , Liang Huang

Protein-ligand interactions (PLIs) are fundamental to biochemical research and their identification is crucial for estimating biophysical and biochemical properties for rational therapeutic design. Currently, experimental characterization…

Machine Learning · Statistics 2021-12-01 Carter Knutson , Mridula Bontha , Jenna A. Bilbrey , Neeraj Kumar

Viral infections are causing significant morbidity and mortality worldwide. Understanding the interaction patterns between a particular virus and human proteins plays a crucial role in unveiling the underlying mechanism of viral infection…

Machine Learning · Computer Science 2021-11-30 Thi Ngan Dong , Graham Brogden , Gisa Gerold , Megha Khosla

Learned neural solvers have successfully been used to solve combinatorial optimization and decision problems. More general counting variants of these problems, however, are still largely solved with hand-crafted solvers. To bridge this gap,…

Machine Learning · Computer Science 2020-07-02 Jonathan Kuck , Shuvam Chakraborty , Hao Tang , Rachel Luo , Jiaming Song , Ashish Sabharwal , Stefano Ermon

We show that non-steric molecular interactions between RNA polymerase (RNAP) motors that move simultaneously on the same DNA track determine strongly the kinetics of transcription elongation. With a focus on the role of collisions and…

Biological Physics · Physics 2018-10-03 V. Belitsky , G. M. Schütz
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