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Topology optimization of modular structures and mechanisms enables balancing the performance of automatically-generated individualized designs, as required by Industry 4.0, with enhanced sustainability by means of component reuse. For…

Materials Science · Physics 2022-05-25 Marek Tyburec , Martin Doškář , Jan Zeman , Martin Kružík

Neural manifolds summarize the intrinsic structure of the information encoded by a population of neurons. Advances in experimental techniques have made simultaneous recordings from multiple brain regions increasingly commonplace, raising…

Neurons and Cognition · Quantitative Biology 2025-03-27 Iris H. R. Yoon , Gregory Henselman-Petrusek , Yiyi Yu , Robert Ghrist , Spencer LaVere Smith , Chad Giusti

Animal locomotion is often subject to constraints arising from anatomical/physiological asymmetries. We use the nematode C.~elegans as a minimal model system to ask whether such constraints might shape locomotion patterns optimized during…

Neurons and Cognition · Quantitative Biology 2024-01-17 W. Mathijs Rozemuller , Steffen Werner , Antonio Carlos Costa , Liam O'Shaughnessy , Greg J. Stephens , Thomas S. Shimizu

Synchronization is studied in a spatially-distributed network of weekly-coupled, excitatory neurons of Hodgkin-Huxley type. All neurons are coupled to each other synaptically with a fixed time delay and a coupling strength inversely…

Soft Condensed Matter · Physics 2007-05-23 Yuqing Wang , Z. D. Wang , Y. -X. Li , X. Pei

The cerebrospinal fluid (CSF) constitutes an interface through which chemical cues can reach and modulate the activity of neurons located at the epithelial boundary within the entire nervous system. Here, we investigate the role and…

Neurons and Cognition · Quantitative Biology 2018-12-04 Kevin Fidelin , Lydia Djenoune , Caleb Stokes , Andrew Prendergast , Johanna Gómez , Audrey Baradel , Filippo Del bene , Claire Wyart

We study the structural properties of the neural network of the C.elegans (worm) from a directed graph point of view. The Google matrix analysis is used to characterize the neuron connectivity structure and node classifications are…

Physics and Society · Physics 2014-05-07 Vivek Kandiah , Dima L. Shepelyansky

This project investigates whether functional specialization or modularity can support the development of multiple behaviors. In principle, modular solutions of this type can facilitate the development of multiple behaviors since each module…

Robotics · Computer Science 2020-06-12 Victor Massagué Respall

We perform a numerical study on the application of electromagnetic flux on a heterogeneous network of Chialvo neurons represented by a ring-star topology. Heterogeneities are realized by introducing additive noise modulations on both the…

Dynamical Systems · Mathematics 2024-02-09 Indranil Ghosh , Sishu Shankar Muni , Hammed Olawale Fatoyinbo

Understanding how brain networks learn and manage multiple tasks simultaneously is of interest in both neuroscience and artificial intelligence. In this regard, a recent research thread in theoretical neuroscience has focused on how…

Neurons and Cognition · Quantitative Biology 2024-08-05 Giacomo Vedovati , ShiNung Ching

We present a theoretical study aiming at model fitting for sensory neurons. Conventional neural network training approaches are not applicable to this problem due to lack of continuous data. Although the stimulus can be considered as a…

Neurons and Cognition · Quantitative Biology 2017-09-28 R. Ozgur Doruk , Kechen Zhang

Many neural systems display cascading behavior characterized by uninterrupted sequences of neuronal firing. This gap precludes an understanding of how variations in network structure manifest in neural dynamics and either support or impinge…

Neurons and Cognition · Quantitative Biology 2019-11-12 Harang Ju , Jason Z. Kim , Danielle S. Bassett

Convolutional neural networks (CNNs) have been shown to be state-of-the-art models for visual cortical neurons. Cortical neurons in the primary visual cortex are sensitive to contextual information mediated by extensive horizontal and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Isaac Lin , Tianye Wang , Shang Gao , Shiming Tang , Tai Sing Lee

For any motivic $\mathbb{E}_\infty$-ring spectrum $A$ we construct an equivalence $\rho$ between the $\infty$-category of cellular motivic $A$-module spectra and modules over an $\mathbb{E}_1$-algebra $\Theta$ in $\mathbb{Z} $-graded…

Algebraic Topology · Mathematics 2024-09-05 Hadrian Heine

Many neurons in the visual cortex are orientation-selective, increase their firing rate with contrast and are modulated by attention. What is the cortical circuit that underlies these computations? We examine how synchrony can be modulated…

Neurons and Cognition · Quantitative Biology 2007-05-23 Paul H. E. Tiesinga , Calin I. Buia

The human brain has been studied at multiple scales, from neurons, circuits, areas with well defined anatomical and functional boundaries, to large-scale functional networks which mediate coherent cognition. In a recent work, we addressed…

Biological Physics · Physics 2012-05-17 Lazaros K. Gallos , Mariano Sigman , Hernan A. Makse

There is renewed interest in modeling and understanding the nervous system of the nematode $\textit{Caenorhabditis elegans}$ ($\textit{C. elegans}$), as this small model system provides a path to bridge the gap between nervous system…

Neurons and Cognition · Quantitative Biology 2025-05-20 Quilee Simeon , Anshul Kashyap , Konrad P Kording , Edward S Boyden

The observed spatio-temporal ciliary beat patterns on multiciliated epithelia are suspected to be the result of self-organizing processes on various levels. Here, we present an abstract epithelium model at the pluricellular level, which…

Soft Condensed Matter · Physics 2019-07-30 Martin Schneiter , Jaroslav Ricka , Martin Frenz

Compliant environments can mediate interactions between mechanically active cells like fibroblasts. Starting with a phenomenological model for the behaviour of single cells, we use extensive Monte Carlo simulations to predict non-trivial…

Soft Condensed Matter · Physics 2007-05-23 I. B. Bischofs , U. S. Schwarz

Partial synchronization plays a crucial role in the functioning of neuronal networks: selective, coordinated activation of neurons enables information processing that flexibly adapts to a changing computational context. Since the structure…

Neurons and Cognition · Quantitative Biology 2025-06-17 Daniil Radushev , Olesia Dogonasheva , Boris Gutkin , Denis Zakharov

The relationship between the regulatory design and the functionality of molecular networks is a key issue in biology. Modules and motifs have been associated to various cellular processes, thereby providing anecdotal evidence for…

Molecular Networks · Quantitative Biology 2008-03-04 Jacob Bock Axelsen , Sebastian Bernhardsson , Kim Sneppen