English
Related papers

Related papers: Digging Deeper: Methodologies for High-Content Phe…

200 papers

The evolution of biological morphology is critical for understanding the diversity of the natural world, yet traditional analyses often involve subjective biases in the selection and coding of morphological traits. This study employs deep…

Populations and Evolution · Quantitative Biology 2026-02-10 Jiao Sun

Caenorhabditis elegans (C. elegans) illustrated remarkable behavioral plasticities including complex non-associative and associative learning representations. Understanding the principles of such mechanisms presumably leads to constructive…

Neurons and Cognition · Quantitative Biology 2017-03-28 Ramin M. Hasani , Magdalena Fuchs , Victoria Beneder , Radu Grosu

The beet cyst nematode (BCN) Heterodera schachtii is a plant pest responsible for crop loss on a global scale. Here, we introduce a high-throughput system based on computer vision that allows quantifying BCN infestation and characterizing…

Image and Video Processing · Electrical Eng. & Systems 2021-10-15 Long Chen , Matthias Daub , Hans-Georg Luigs , Marcus Jansen , Martin Strauch , Dorit Merhof

We analyse the neural dynamics and its relation with the emergent behaviour of a robotic vehicle that is controlled by a neural network numerical simulation based on the nervous system of the nematode Caenorhabditis elegans. The robot…

Neurons and Cognition · Quantitative Biology 2020-11-19 Carlos E. Valencia Urbina , Sergio A. Cannas , Pablo M. Gleiser

Several approaches were proposed to describe the geomorphology of drainage networks and the abiotic/biotic factors determining their morphology. There is an intrinsic complexity of the explicit qualification of the morphological variations…

Deep learning has become a powerful tool in computational biology, revolutionising the analysis and interpretation of biological data over time. In our article review, we delve into various aspects of deep learning in computational biology.…

Thanks to recent progress in high-throughput experimental techniques, the datasets of large-scale protein interactions of prototypical multicellular species, the nematode worm Caenorhabditis elegans and the fruit fly Drosophila…

Molecular Networks · Quantitative Biology 2009-11-11 K. -I. Goh , B. Kahng , D. Kim

What role does phenotypic complexity play in the systems-level function of an embodied agent? The organismal phenotype is a topologically complex structure that interacts with a genotype, developmental physics, and an informational…

Neurons and Cognition · Quantitative Biology 2022-08-15 Bradly Alicea , Jesse Parent

Nematode worms are one of most abundant metazoan groups on the earth, occupying diverse ecological niches. Accurate recognition or identification of nematodes are of great importance for pest control, soil ecology, bio-geography, habitat…

Quantitative Methods · Quantitative Biology 2021-03-16 Xuequan Lu , Yihao Wang , Sheldon Fung , Xue Qing

Cell movement in the early phase of C. elegans development is regulated by a highly complex process in which a set of rules and connections are formulated at distinct scales. Previous efforts have shown that agent-based, multi-scale…

Quantitative Methods · Quantitative Biology 2018-05-11 Zi Wang , Dali Wang , Chengcheng Li , Yichi Xu , Husheng Li , Zhirong Bao

Behavioural phenotyping of Drosophila is an important means in biological and medical research to identify genetic, pathologic or psychologic impact on animal behaviour.

Computer Vision and Pattern Recognition · Computer Science 2019-08-05 Ziping Jiang , Paul L. Chazot , M. Emre Celebi , Danny Crookes , Richard Jiang

Finding an optimal correspondence between point sets is a common task in computer vision. Existing techniques assume relatively simple relationships among points and do not guarantee an optimal match. We introduce an algorithm capable of…

Computer Vision and Pattern Recognition · Computer Science 2023-01-11 Andrew Lauziere , Ryan Christensen , Hari Shroff , Radu Balan

Post-genomic research deals with challenging problems in screening genomes of organisms for particular functions or potential for being the targets of genetic engineering for desirable biological features. 'Phenotyping' of wild type and…

Quantitative Methods · Quantitative Biology 2010-09-06 Hesam T. Dashti , Jernej Tonejc , Adel Ardalan , Alireza F. Siahpirani , Sabrina Guettes , Zohreh Sharif , Liya Wang , Amir H. Assadi

Accurate evaluation of human aesthetic preferences represents a major challenge for creative evolutionary and generative systems research. Prior work has tended to focus on feature measures of the artefact, such as symmetry, complexity and…

Neural and Evolutionary Computing · Computer Science 2020-09-28 Jon McCormack , Andy Lomas

Recovering 3D phase features of complex, multiple-scattering biological samples traditionally sacrifices computational efficiency and processing time for physical model accuracy and reconstruction quality. This trade-off hinders the rapid…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Alex Matlock , Lei Tian

The folding of RNA and DNA strands plays crucial roles in biological systems and bionanotechnology. However, studying these processes with high-resolution numerical models is beyond current computational capabilities due to the timescales…

Soft Condensed Matter · Physics 2024-02-07 F. Tosti Guerra , E. Poppleton , P. Šulc , L. Rovigatti

Capturing intricate biological phenomena often requires multiscale modeling where coarse and inexpensive models are developed using limited components of expensive and high-fidelity models. Here, we consider such a multiscale framework in…

Quantitative Methods · Quantitative Biology 2022-07-12 Konstantia Georgouli , Helgi I Ingólfsson , Fikret Aydin , Mark Heimann , Felice C Lightstone , Peer-Timo Bremer , Harsh Bhatia

Deep unfolding is a method of growing popularity that fuses iterative optimization algorithms with tools from neural networks to efficiently solve a range of tasks in machine learning, signal and image processing, and communication systems.…

Signal Processing · Electrical Eng. & Systems 2019-10-09 Alexios Balatsoukas-Stimming , Christoph Studer

We investigate how locomotory behavior is generated in the brain focusing on the paradigmatic connectome of nematode Caenorhabditis elegans (C. elegans) and on neuronal activity patterns that control forward locomotion. We map the neuronal…

Adaptation and Self-Organizing Systems · Physics 2020-06-17 Thomas Maertens , Eckehard Schöll , Jorge Ruiz , Philipp Hövel

Inspired by the human ability to learn and organize knowledge into hierarchical taxonomies with prototypes, this paper addresses key limitations in current deep hierarchical clustering methods. Existing methods often tie the structure to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Zekun Wang , Ethan Haarer , Tianyi Zhu , Zhiyi Dai , Christopher J. MacLellan