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High-strength composite hydrogels cellulose-polyacrylamide were synthesized by free-radical polymerization of acrylamide conducted inside the previously formed physical network of regenerated plant cellulose. Partial hydrolysis of the amide…

Hydrogels are biphasic, swollen polymer networks where elastic deformation is coupled to nanoscale fluid flow. As a consequence, hydrogels can withstand large strains and exhibit nonlinear, hyperelastic properties. For low-modulus hydrogel…

Soft Condensed Matter · Physics 2024-10-23 Jing Wang , Justin C. Burton

It is established that the mechanical properties of hydrogels control the fate of (stem) cells. However, despite its importance, a one-to-one correspondence between gels' stiffness and cell behaviour is still missing from literature. In…

Contraction assay based on surface measurement have been widely used to evaluate cell contractility in 3D models. This method is straightforward and requires no specific equipment, but it does not provide quantitative data about contraction…

An unusual type of mechanical behavior was registered while studying the swollen hydrogel compositions "cellulose-polyacrylamide" in the conditions of multiple cyclic compression tests with the broad variation of the deformation speed.…

Soft Condensed Matter · Physics 2016-11-09 I. V. Gofman , A. L. Buyanov

Hydrogels are increasingly recognized as a versatile platform for applications spanning from tissue engineering to soft robotics or flexible electronics. Recent efforts have focused on enhancing and tailoring their mechanical performance to…

Soft Condensed Matter · Physics 2025-12-29 Agniva Dutta , Valeriy V. Ginzburg , Gleb Vasilyev , Eyal Zussman

Implantable hydrogels should ideally possess mechanical properties matched to the surrounding tissues to enable adequate mechanical function while regeneration occurs. This can be challenging, especially when degradable systems with high…

Tissues and Organs · Quantitative Biology 2024-03-19 Michael Phillips , Giuseppe Tronci , Christopher M. Pask , Stephen J. Russell

The submicron- and micron-scale structures of composite hydrogels based on bacterial cellulose (BC) and polyacrylamide were studied by spin-echo small-angle neutron scattering (SESANS). These hydrogels were synthesized via free-radical…

Chemical Physics · Physics 2016-08-02 E. V. Velichko , A. L. Buyanov , Yu. O. Chetverikov , C. P. Duif , W. G. Bouwman , R. Yu. Smyslov

Hydrogels have had a profound impact in the fields of tissue engineering, drug delivery, and materials science as a whole. Due to the network architecture of these materials, imbibement with water often results in uniform swelling and…

Bacterial cellulose is an important class of biomaterials which can be grown in well-controlled laboratory and industrial conditions. The cellulose structure is affected by several biological, chemical and environmental factors, including…

Biological Physics · Physics 2021-07-28 Sung-Ha Hong , Jia Yang , Mahdi Davoodianidalik , Horst Punzmann , Michael Shats , Hua Xia

Inspired by the cellular design of plant tissue, we present a new approach to make versatile, tough, highly water-swelling composites. We embed highly swelling hydrogel particles inside tough, water-permeable, elastomeric matrices. The…

Tissue engineering aims to grow artificial tissues \emph{in vitro} to replace those in the body that have been damaged through age, trauma or disease. A recent approach to engineer artificial cartilage involves seeding cells within a…

Soft Condensed Matter · Physics 2017-12-05 M. J. Chen , L. S. Kimpton , J. P. Whiteley , M. Castilho , J. Malda , C. P. Please , S. L. Waters , H. M. Byrne

Many bacterial species are helical in form, including the widespread pathogen H. pylori. Motivated by recent experiments on H. pylori showing that cell wall synthesis is not uniform, we investigate the possible formation of helical cell…

Soft Condensed Matter · Physics 2024-01-15 Cesar L. Pastrana , Luyi Qiu , Shahaf Armon , Ulrich Gerland , Ariel Amir

The role of electrostatics on the interfacial properties of polyelectrolyte microgels has been discussed controversially in the literature. It is not yet clear if, or how, Coulomb interactions affect their behavior under interfacial…

Microgels are soft colloidal particles constituted by cross-linked polymer networks with a high potential for applications. In particular, after adsorption at a fluid interface, interfacial tension provides two-dimensional (2D) confinement…

Soft Condensed Matter · Physics 2021-09-03 Jacopo Vialetto , Natalie Nussbaum , Jotam Bergfreund , Peter Fischer , Lucio Isa

Hydrogels are attractive and versatile gel-based structures consisting of three-dimensional networks of hydrophilic polymers with unique properties that can retain a large amount of water and be tailor-designed according to specific…

Active materials capable of autonomously modulating their mechanical properties are foundational to the development of next-generation soft technologies. Here, we introduce a novel class of extensible biohybrid hydrogels powered by living…

Tissue-like materials are required in many robotic systems to improve human-machine interactions. However, the mechanical properties of living tissues are difficult to replicate. Synthetic materials are not usually capable of simultaneously…

Biological hydrogels have been increasingly sought after as e.g. wound dressings or scaffolds for regenerative medicine, due to their inherent biofunctionality in biological environments. Especially in moist wound healing, the ideal…

Chemical Physics · Physics 2014-10-24 Giuseppe Tronci , Colin A. Grant , Neil H. Thomson , Stephen J. Russell , David J. Wood

Hydrogels are promising systems for separation applications due to their structural characteristics (i.e. hydrophilicity and porosity). In our study, we investigate the permeation of suspensions of rigid latex particles of different sizes…

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