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DNA sequence encoding is fundamental to gene function prediction, protein synthesis, and diverse downstream biological tasks. Despite the substantial progress achieved by large-scale DNA sequence pretraining, existing studies have…

Machine Learning · Computer Science 2026-04-21 Zhijiang Tang , Jiaxin Qi , Yan Cui , Jinli Ou , Yuhua Zheng , Jianqiang Huang

Deep Neural Network (DNN) has been showing great potential in kinds of real-world applications such as fraud detection and distress prediction. Meanwhile, data isolation has become a serious problem currently, i.e., different parties cannot…

Machine Learning · Computer Science 2020-03-13 Longfei Zheng , Chaochao Chen , Yingting Liu , Bingzhe Wu , Xibin Wu , Li Wang , Lei Wang , Jun Zhou , Shuang Yang

Precision medicine is an emerging approach for disease treatment and prevention that delivers personalized care to individual patients by considering their genetic makeups, medical histories, environments, and lifestyles. Despite the rapid…

Machine Learning · Computer Science 2021-11-11 William Briguglio , Parisa Moghaddam , Waleed A. Yousef , Issa Traore , Mohammad Mamun

Differential privacy (DP) is widely employed to provide privacy protection for individuals by limiting information leakage from the aggregated data. Two well-known models of DP are the central model and the local model. The former requires…

Cryptography and Security · Computer Science 2024-11-05 Yucheng Fu , Tianhao Wang

While the introduction of differential privacy has been a major breakthrough in the study of privacy preserving data publication, some recent work has pointed out a number of cases where it is not possible to limit inference about…

Databases · Computer Science 2012-02-16 Ada Wai-Chee Fu , Jia Wang , Ke Wang , Raymond Chi-Wing Wong

Consider two parties who want to compare their strings, e.g., genomes, but do not want to reveal them to each other. We present a system for privacy-preserving matching of strings, which differs from existing systems by providing a…

Cryptography and Security · Computer Science 2013-02-13 Martin Beck , Florian Kerschbaum

With the emergence of smart cities, Internet of Things (IoT) devices as well as deep learning technologies have witnessed an increasing adoption. To support the requirements of such paradigm in terms of memory and computation, joint and…

Networking and Internet Architecture · Computer Science 2020-10-27 Emna Baccour , Aiman Erbad , Amr Mohamed , Mounir Hamdi , Mohsen Guizani

The DNA cryptography is a new and very promising direction in cryptography research. DNA can be used in cryptography for storing and transmitting the information, as well as for computation. Although in its primitive stage, DNA cryptography…

Cryptography and Security · Computer Science 2012-03-07 Kang Ning

Statistical model checking is a class of sequential algorithms that can verify specifications of interest on an ensemble of cyber-physical systems (e.g., whether 99% of cars from a batch meet a requirement on their energy efficiency). These…

Machine Learning · Computer Science 2022-06-29 Yu Wang , Hussein Sibai , Mark Yen , Sayan Mitra , Geir E. Dullerud

DNA sequencing is becoming increasingly commonplace, both in medical and direct-to-consumer settings. To promote discovery, collected genomic data is often de-identified and shared, either in public repositories, such as OpenSNP, or with…

Machine Learning · Computer Science 2022-12-21 Rajagopal Venkatesaramani , Bradley A. Malin , Yevgeniy Vorobeychik

Performing computations while maintaining privacy is an important problem in todays distributed machine learning solutions. Consider the following two set ups between a client and a server, where in setup i) the client has a public data…

Machine Learning · Computer Science 2022-01-27 Praneeth Vepakomma , Julia Balla , Ramesh Raskar

By using the Jensen-Shannon divergence, genomic DNA can be divided into compositionally distinct domains through a standard recursive segmentation procedure. Each domain, while significantly different from its neighbours, may however share…

Biological Physics · Physics 2009-11-07 Rajeev K. Azad , J. Subba Rao , Wentian Li , Ramakrishna Ramaswamy

Hardening data protection using multiple methods rather than 'just' encryption is of paramount importance when considering continuous and powerful attacks in order to observe, steal, alter, or even destroy private and confidential…

Cryptography and Security · Computer Science 2017-02-14 Gerard Memmi , Katarzyna Kapusta , Patrick Lambein , Han Qiu

Differential privacy comes equipped with multiple analytical tools for the design of private data analyses. One important tool is the so-called "privacy amplification by subsampling" principle, which ensures that a differentially private…

Machine Learning · Computer Science 2018-11-26 Borja Balle , Gilles Barthe , Marco Gaboardi

Large genomic datasets are now created through numerous activities, including recreational genealogical investigations, biomedical research, and clinical care. At the same time, genomic data has become valuable for reuse beyond their…

Cryptography and Security · Computer Science 2021-12-28 Rajagopal Venkatesaramani , Zhiyu Wan , Bradley A. Malin , Yevgeniy Vorobeychik

A new collaborative learning, called split learning, was recently introduced, aiming to protect user data privacy without revealing raw input data to a server. It collaboratively runs a deep neural network model where the model is split…

Cryptography and Security · Computer Science 2020-03-30 Sharif Abuadbba , Kyuyeon Kim , Minki Kim , Chandra Thapa , Seyit A. Camtepe , Yansong Gao , Hyoungshick Kim , Surya Nepal

The Domain Name System (DNS) is central to all Internet user activity, resolving accessed domain names into Internet Protocol (IP) addresses. As a result, curious DNS resolvers can learn everything about Internet users' interests. Public…

Cryptography and Security · Computer Science 2025-09-30 Philip Sjösvärd , Hongyu Jin , Panos Papadimitratos

DNA sequencing is revolutionising the field of medicine. DNA sequencers, the machines which perform DNA sequencing, have evolved from the size of a fridge to that of a mobile phone over the last two decades. The cost of sequencing a human…

Genomics · Quantitative Biology 2021-01-14 Hasindu Gamaarachchi

Nowadays, machine learning models and applications have become increasingly pervasive. With this rapid increase in the development and employment of machine learning models, a concern regarding privacy has risen. Thus, there is a legitimate…

Machine Learning · Computer Science 2022-11-22 Samah Baraheem , Zhongmei Yao

In real-world, our DNA is unique but many people share names. This phenomenon often causes erroneous aggregation of documents of multiple persons who are namesake of one another. Such mistakes deteriorate the performance of document…

Social and Information Networks · Computer Science 2017-09-12 Baichuan Zhang , Mohammad Al Hasan