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Optical coherence tomography (OCT) is a noninvasive imaging modality which can be used to obtain depth images of the retina. The changing layer thicknesses can thus be quantified by analyzing these OCT images, moreover these changes have…

Computer Vision and Pattern Recognition · Computer Science 2018-03-15 Yufan He , Aaron Carass , Bruno M. Jedynak , Sharon D. Solomon , Shiv Saidha , Peter A. Calabresi , Jerry L. Prince

Optical Coherence Tomography (OCT) is one of the most important retinal imaging technique. However, involuntary motion artifacts still pose a major challenge in OCT imaging that compromises the quality of downstream analysis, such as…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Yiqian Wang , Alexandra Warter , Melina Cavichini , Varsha Alex , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

Retinopathy represents a group of retinal diseases that, if not treated timely, can cause severe visual impairments or even blindness. Many researchers have developed autonomous systems to recognize retinopathy via fundus and optical…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Taimur Hassan , Bilal Hassan , Muhammad Usman Akram , Shahrukh Hashmi , Abdel Hakim Taguri , Naoufel Werghi

The automatic segmentation of retinal layer structures enables clinically-relevant quantification and monitoring of eye disorders over time in OCT imaging. Eyes with late-stage diseases are particularly challenging to segment, as their…

Computer Vision and Pattern Recognition · Computer Science 2017-07-18 Stefanos Apostolopoulos , Sandro De Zanet , Carlos Ciller , Sebastian Wolf , Raphael Sznitman

Purpose: We proposed a deep convolutional neural network (CNN), named Retinal Fluid Segmentation Network (ReF-Net) to segment volumetric retinal fluid on optical coherence tomography (OCT) volume. Methods: 3 x 3-mm OCT scans were acquired…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Yukun Guo , Tristan T. Hormel , Honglian Xiong , Jie Wang , Thomas S. Hwang , Yali Jia

Convolutional Neural Network models have successfully detected retinal illness from optical coherence tomography (OCT) and fundus images. These CNN models frequently rely on vast amounts of labeled data for training, difficult to obtain,…

Computer Vision and Pattern Recognition · Computer Science 2022-01-28 Sourya Dipta Das , Saikat Dutta , Nisarg A. Shah , Dwarikanath Mahapatra , Zongyuan Ge

Layer segmentation is important to quantitative analysis of retinal optical coherence tomography (OCT). Recently, deep learning based methods have been developed to automate this task and yield remarkable performance. However, due to the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Hong Liu , Dong Wei , Donghuan Lu , Xiaoying Tang , Liansheng Wang , Yefeng Zheng

Optical Coherence Tomography (OCT) is the primary imaging modality for detecting pathological biomarkers associated to retinal diseases such as Age-Related Macular Degeneration. In practice, clinical diagnosis and treatment strategies are…

Computer Vision and Pattern Recognition · Computer Science 2019-07-17 Thomas Kurmann , Pablo Márquez-Neila , Siqing Yu , Marion Munk , Sebastian Wolf , Raphael Sznitman

Our objective is to evaluate the efficacy of methods that use deep learning (DL) for the automatic fine-grained segmentation of optical coherence tomography (OCT) images of the retina. OCT images from 10 patients with mild non-proliferative…

Computer Vision and Pattern Recognition · Computer Science 2018-01-31 Mike Pekala , Neil Joshi , David E. Freund , Neil M. Bressler , Delia Cabrera DeBuc , Philippe M Burlina

In this paper, we propose a framework that incorporates experts diagnostics and insights into the analysis of Optical Coherence Tomography (OCT) using multi-modal learning. To demonstrate the effectiveness of this approach, we create a…

Image and Video Processing · Electrical Eng. & Systems 2022-03-22 Y. Logan , K. Kokilepersaud , G. Kwon , G. AlRegib , C. Wykoff , H. Yu

Retinal diseases are a leading cause of vision impairment and blindness, with timely diagnosis being critical for effective treatment. Optical Coherence Tomography (OCT) has become a standard imaging modality for retinal disease diagnosis,…

Image and Video Processing · Electrical Eng. & Systems 2025-10-06 Jilan Cheng , Guoli Long , Zeyu Zhang , Zhenjia Qi , Hanyu Wang , Libin Lu , Shuihua Wang , Yudong Zhang , Jin Hong

Optical coherence tomography (OCT) is a commonly-used method of extracting high resolution retinal information. Moreover there is an increasing demand for the automated retinal layer segmentation which facilitates the retinal disease…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Zeyu Fu , Yang Sun , Xiangyu Zhang , Scott Stainton , Shaun Barney , Jeffry Hogg , William Innes , Satnam Dlay

Optical Coherence Tomography (OCT) is an emerging technique in the field of biomedical imaging, with applications in ophthalmology, dermatology, coronary imaging etc. Due to the underlying physics, OCT images usually suffer from a granular…

Computer Vision and Pattern Recognition · Computer Science 2015-02-10 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

Automatic retinal layer segmentation with medical images, such as optical coherence tomography (OCT) images, serves as an important tool for diagnosing ophthalmic diseases. However, it is challenging to achieve accurate segmentation due to…

Image and Video Processing · Electrical Eng. & Systems 2024-04-26 Xiang He , Weiye Song , Yiming Wang , Fabio Poiesi , Ji Yi , Manishi Desai , Quanqing Xu , Kongzheng Yang , Yi Wan

Optical Coherence Tomography (OCT) provides high-resolution cross-sectional images useful for diagnosing various diseases, but their distinct characteristics from natural images raise questions about whether large-scale pre-training on…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Zihao Han , Philippe De Wilde

Purpose: To test the feasibility of using deep learning for optical coherence tomography angiography (OCTA) detection of diabetic retinopathy (DR). Methods: A deep learning convolutional neural network (CNN) architecture VGG16 was employed…

Quantitative Methods · Quantitative Biology 2021-12-16 David Le , Minhaj Alam , Cham Yao , Jennifer I. Lim , R. V. P. Chan , Devrim Toslak , Xincheng Yao

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

Ophthalmological imaging utilizes different imaging systems, such as color fundus, infrared, fluorescein angiography, optical coherence tomography (OCT) or OCT angiography. Multiple images with different modalities or acquisition times are…

Image and Video Processing · Electrical Eng. & Systems 2022-01-10 Aline Sindel , Bettina Hohberger , Sebastian Fassihi Dehcordi , Christian Mardin , Robert Lämmer , Andreas Maier , Vincent Christlein

Optical coherence tomography (OCT) is one of the non-invasive and easy-to-acquire biomarkers (the thickness of the retinal layers, which is detectable within OCT scans) being investigated to diagnose Alzheimer's disease (AD). This work aims…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Paria Jeihouni , Omid Dehzangi , Annahita Amireskandari , Ali Dabouei , Ali Rezai , Nasser M. Nasrabadi

Objective: The advent of Electronic Medical Records (EMR) with large electronic imaging databases along with advances in deep neural networks with machine learning has provided a unique opportunity to achieve milestones in automated image…

Machine Learning · Statistics 2016-12-16 Cecilia S. Lee , Doug M. Baughman , Aaron Y. Lee