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In this paper, we investigate image reconstruction for dynamic Computed Tomography. The motion of the target with respect to the measurement acquisition rate leads to highly resolved in time but highly undersampled in space measurements.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-27 Pablo Arratia , Matthias Ehrhardt , Lisa Kreusser

Individual Neurons in the nervous systems exploit various dynamics. To capture these dynamics for single neurons, we tune the parameters of an electrophysiological model of nerve cells, to fit experimental data obtained by calcium imaging.…

Quantitative Methods · Quantitative Biology 2017-11-07 Magdalena Fuchs , Manuel Zimmer , Radu Grosu , Ramin M. Hasani

In scientific applications, multivariate observations often come in tandem with temporal or spatial covariates, with which the underlying signals vary smoothly. The standard approaches such as principal component analysis and factor…

Statistics Theory · Mathematics 2019-10-15 Mark Koudstaal , Dengdeng Yu , Dehan Kong , Fang Yao

In safety-critical applications like medical diagnosis, certainty associated with a model's prediction is just as important as its accuracy. Consequently, uncertainty estimation and reduction play a crucial role. Uncertainty in predictions…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Abhishek Singh Sambyal , Narayanan C. Krishnan , Deepti R. Bathula

The reconstruction of dynamic positron emission tomography (PET) images from noisy projection data is a significant but challenging problem. In this paper, we introduce an unsupervised learning approach, Non-negative Implicit Neural…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Chaozhi Zhang , Wenxiang Ding , Roy Y. He , Xiaoqun Zhang , Qiaoqiao Ding

Advances in modern technology have enabled the simultaneous recording of neural spiking activity, which statistically can be represented by a multivariate point process. We characterise the second order structure of this process via the…

Methodology · Statistics 2024-04-30 Carla Pinkney , Carolina Euan , Alex Gibberd , Ali Shojaie

The meteoric rise in the adoption of deep neural networks as computational models of vision has inspired efforts to "align" these models with humans. One dimension of interest for alignment includes behavioral choices, but moving beyond…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Lore Goetschalckx , Lakshmi Narasimhan Govindarajan , Alekh Karkada Ashok , Aarit Ahuja , David L. Sheinberg , Thomas Serre

Two-photon imaging of calcium indicators allows simultaneous recording of responses of hundreds of neurons over hours and even days, but provides a relatively indirect measure of their spiking activity. Existing deconvolution algorithms…

Neurons and Cognition · Quantitative Biology 2016-01-05 Elad Ganmor , Michael Krumin , Luigi F. Rossi , Matteo Carandini , Eero P. Simoncelli

While the interaction of ultra-intense ultra-short laser pulses with near- and overcritical plasmas cannot be directly observed, experimentally accessible quantities (observables) often only indirectly give information about the underlying…

Plasma Physics · Physics 2022-12-13 Thomas Miethlinger , Nico Hoffmann , Thomas Kluge

Adaptive nuclear-norm penalization is proposed for low-rank matrix approximation, by which we develop a new reduced-rank estimation method for the general high-dimensional multivariate regression problems. The adaptive nuclear norm of a…

Methodology · Statistics 2012-09-25 Kun Chen , Hongbo Dong , Kung-Sik Chan

The aim of this paper is to establish a nonlinear variational approach to the reconstruction of moving density images from indirect dynamic measurements. Our approach is to model the dynamics as a hyperelastic deformation of an initial…

Numerical Analysis · Mathematics 2015-12-01 Martin Burger , Jan Modersitzki , Sebastian Suhr

Traditional computational methods, such as the finite element analysis, have provided valuable insights into uncovering the underlying mechanisms of brain physical behaviors. However, precise predictions of brain physics require effective…

Machine Learning · Computer Science 2023-10-18 Jixin Hou , Nicholas Filla , Xianyan Chen , Mir Jalil Razavi , Tianming Liu , Xianqiao Wang

Nuclear magnetic resonance (NMR) spectroscopy provides detailed information pertaining to dynamic processes through line-shape changes, which have been traditionally limited to equilibrium conditions. However, there is a wealth of…

Ultrasound and radar signals are highly beneficial for medical imaging as they are non-invasive and non-ionizing. Traditional imaging techniques have limitations in terms of contrast and physical interpretation. Quantitative medical imaging…

Computer Vision and Pattern Recognition · Computer Science 2024-02-19 Tom Sharon , Yonina C. Eldar

Dynamic magnetic resonance imaging (dMRI) captures temporally-resolved anatomy but is often challenged by limited sampling and motion-induced artifacts. Conventional motion-compensated reconstructions typically rely on pre-estimated optical…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Baoqing Li , Yuanyuan Liu , Congcong Liu , Qingyong Zhu , Jing Cheng , Yihang Zhou , Hao Chen , Zhuo-Xu Cui , Dong Liang

The human brain is a complex system requiring both macroscopic and microscopic components for comprehensive understanding. However, mapping nonlinear relationships between these scales remains challenging due to technical limitations and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-28 Sooyoung Kim , Joonwoo Kwon , Junbeom Kwon , Jungyoun Janice Min , Sangyoon Bae , Yuewei Lin , Shinjae Yoo , Jiook Cha

A key property of neural networks is their capacity of adapting to data during training. Yet, our current mathematical understanding of feature learning and its relationship to generalization remain limited. In this work, we provide a…

Machine Learning · Statistics 2024-10-25 Yatin Dandi , Luca Pesce , Hugo Cui , Florent Krzakala , Yue M. Lu , Bruno Loureiro

Nonparametric density estimation is an unsupervised learning problem. In this work we propose a two-step procedure that casts the density estimation problem in the first step into a supervised regression problem. The advantage is that we…

Statistics Theory · Mathematics 2024-06-04 Thijs Bos , Johannes Schmidt-Hieber

A primary interest in dynamic inverse problems is to identify the underlying temporal behaviour of the system from outside measurements. In this work we consider the case, where the target can be represented by a decomposition of spatial…

Numerical Analysis · Mathematics 2020-06-09 Simon Arridge , Pascal Fernsel , Andreas Hauptmann

We describe novel subgradient methods for a broad class of matrix optimization problems involving nuclear norm regularization. Unlike existing approaches, our method executes very cheap iterations by combining low-rank stochastic…

Machine Learning · Computer Science 2012-07-03 Haim Avron , Satyen Kale , Shiva Kasiviswanathan , Vikas Sindhwani